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Yuwen Zhu

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-SRG
Phone303/724-7950

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tian Y, Sun Y, Gao F, Koenig MR, Sunderland A, Fujiwara Y, Torphy RJ, Chen L, Edil BH, Schulick RD, Zhu Y. CD28H expression identifies resident memory CD8 + T cells with less cytotoxicity in human peripheral tissues and cancers. Oncoimmunology. 2019; 8(2):e1538440. PMID: 30713797.
      View in: PubMed
    2. Fujiwara Y, Sun Y, Torphy RJ, He J, Yanaga K, Edil BH, Schulick RD, Zhu Y. Pomalidomide Inhibits PD-L1 Induction to Promote Antitumor Immunity. Cancer Res. 2018 Dec 01; 78(23):6655-6665. PMID: 30315115.
      View in: PubMed
    3. Torphy RJ, Schulick RD, Zhu Y. Newly Emerging Immune Checkpoints: Promises for Future Cancer Therapy. Int J Mol Sci. 2017 Dec 06; 18(12). PMID: 29211042.
      View in: PubMed
    4. Xu F, Sunderland A, Zhou Y, Schulick RD, Edil BH, Zhu Y. Blockade of CD112R and TIGIT signaling sensitizes human natural killer cell functions. Cancer Immunol Immunother. 2017 Oct; 66(10):1367-1375. PMID: 28623459.
      View in: PubMed
    5. Zhu Y, Yao S, Augustine MM, Xu H, Wang J, Sun J, Broadwater M, Ruff W, Luo L, Zhu G, Tamada K, Chen L. Neuron-specific SALM5 limits inflammation in the CNS via its interaction with HVEM. Sci Adv. 2016 Apr; 2(4):e1500637. PMID: 27152329; PMCID: PMC4846428.
    6. Bastman JJ, Serracino HS, Zhu Y, Koenig MR, Mateescu V, Sams SB, Davies KD, Raeburn CD, McIntyre RC, Haugen BR, French JD. Tumor-Infiltrating T Cells and the PD-1 Checkpoint Pathway in Advanced Differentiated and Anaplastic Thyroid Cancer. J Clin Endocrinol Metab. 2016 07; 101(7):2863-73. PMID: 27045886.
      View in: PubMed
    7. Zhu Y, Paniccia A, Schulick AC, Chen W, Koenig MR, Byers JT, Yao S, Bevers S, Edil BH. Identification of CD112R as a novel checkpoint for human T cells. J Exp Med. 2016 Feb 08; 213(2):167-76. PMID: 26755705; PMCID: PMC4749091.
    8. Yu X, Koenig MR, Zhu Y. Plasma miRNA, an emerging biomarker for pancreatic cancer. Ann Transl Med. 2015 Nov; 3(19):297. PMID: 26697457; PMCID: PMC4671870.
    9. Paniccia A, Merkow J, Edil BH, Zhu Y. Immunotherapy for pancreatic ductal adenocarcinoma: an overview of clinical trials. Chin J Cancer Res. 2015 Aug; 27(4):376-91. PMID: 26361407; PMCID: PMC4560736.
    10. Luo L, Zhu G, Xu H, Yao S, Zhou G, Zhu Y, Tamada K, Huang L, Flies AD, Broadwater M, Ruff W, van Deursen JM, Melero I, Zhu Z, Chen L. B7-H3 Promotes Pathogenesis of Autoimmune Disease and Inflammation by Regulating the Activity of Different T Cell Subsets. PLoS One. 2015; 10(6):e0130126. PMID: 26065426; PMCID: PMC4465912.
    11. Byers JT, Paniccia A, Kaplan J, Koenig M, Kahn N, Wilson L, Chen L, Schulick RD, Edil BH, Zhu Y. Expression of the Novel Costimulatory Molecule B7-H5 in Pancreatic Cancer. Ann Surg Oncol. 2015 Dec; 22 Suppl 3:S1574-9. PMID: 25519928.
      View in: PubMed
    12. Zhu Y, Chen L. CD137 as a biomarker for tumor-reactive T cells: finding gold in the desert. Clin Cancer Res. 2014 Jan 01; 20(1):3-5. PMID: 24166912.
      View in: PubMed
    13. Yao S, Zhu Y, Chen L. Advances in targeting cell surface signalling molecules for immune modulation. Nat Rev Drug Discov. 2013 Feb; 12(2):130-46. PMID: 23370250; PMCID: PMC3698571.
    14. Zhu Y, Yao S, Iliopoulou BP, Han X, Augustine MM, Xu H, Phennicie RT, Flies SJ, Broadwater M, Ruff W, Taube JM, Zheng L, Luo L, Zhu G, Chen J, Chen L. B7-H5 costimulates human T cells via CD28H. Nat Commun. 2013; 4:2043. PMID: 23784006; PMCID: PMC3698612.
    15. Yao S, Zhu Y, Zhu G, Augustine M, Zheng L, Goode DJ, Broadwater M, Ruff W, Flies S, Xu H, Flies D, Luo L, Wang S, Chen L. B7-h2 is a costimulatory ligand for CD28 in human. Immunity. 2011 May 27; 34(5):729-40. PMID: 21530327; PMCID: PMC3103603.
    16. Zhu Y, Yao S, Chen L. Cell surface signaling molecules in the control of immune responses: a tide model. Immunity. 2011 Apr 22; 34(4):466-78. PMID: 21511182; PMCID: PMC3176719.
    17. Narazaki H, Zhu Y, Luo L, Zhu G, Chen L. CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells. Blood. 2010 Mar 11; 115(10):1941-8. PMID: 20068221; PMCID: PMC2837330.
    18. Yao S, Wang S, Zhu Y, Luo L, Zhu G, Flies S, Xu H, Ruff W, Broadwater M, Choi IH, Tamada K, Chen L. PD-1 on dendritic cells impedes innate immunity against bacterial infection. Blood. 2009 Jun 04; 113(23):5811-8. PMID: 19339692; PMCID: PMC2700320.
    19. Zhu Y, Chen L. Turning the tide of lymphocyte costimulation. J Immunol. 2009 Mar 01; 182(5):2557-8. PMID: 19234146.
      View in: PubMed
    20. Huang GN, Huso DL, Bouyain S, Tu J, McCorkell KA, May MJ, Zhu Y, Lutz M, Collins S, Dehoff M, Kang S, Whartenby K, Powell J, Leahy D, Worley PF. NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins. Science. 2008 Jan 25; 319(5862):476-81. PMID: 18218901; PMCID: PMC3602998.
    21. Zhu Y, Zhu G, Luo L, Flies AS, Chen L. CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype. Blood. 2007 Jun 01; 109(11):4882-9. PMID: 17244673; PMCID: PMC1885532.
    22. Choi IH, Zhu G, Sica GL, Strome SE, Cheville JC, Lau JS, Zhu Y, Flies DB, Tamada K, Chen L. Genomic organization and expression analysis of B7-H4, an immune inhibitory molecule of the B7 family. J Immunol. 2003 Nov 01; 171(9):4650-4. PMID: 14568939.
      View in: PubMed
    23. Zhu Y, Chen L. Cancer therapeutic monoclonal antibodies targeting lymphocyte co-stimulatory pathways. Curr Opin Investig Drugs. 2003 Jun; 4(6):691-5. PMID: 12901227.
      View in: PubMed
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