Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Kathryn M Haskins

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-IMM MICRO GENERAL OPER
Phone303/270-2093

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    R23AI022247     (HASKINS, KATHRYN)Sep 30, 1985 - Aug 31, 1986
    NIH/NIAID
    LIPOSOME RECONSTITUTION OF THE T CELL RECEPTOR
    Role: Principal Investigator

    R23AI024530     (HASKINS, KATHRYN)Sep 1, 1986 - Aug 31, 1988
    NIH/NIAID
    LIPOSOME RECONSTITUTION OF THE T CELL RECEPTOR
    Role: Principal Investigator

    R55DK044132     (HASKINS, KATHRYN)Sep 30, 1991 - Apr 30, 1992
    NIH/NIDDK
    ANTIGEN SPECIFICITY OF T CELL CLONES
    Role: Principal Investigator

    T32AI007405     (TORRES, RAUL MARTIN)Sep 30, 1991 - Jul 31, 2021
    NIH/NIAID
    Training Program in Immunology
    Role: Co-Principal Investigator

    R01DK044132     (HASKINS, KATHRYN)May 1, 1992 - Apr 30, 1999
    NIH/NIDDK
    ANTIGEN SPECIFICITY OF T CELL CLONES FROM THE NOD MOUSE
    Role: Principal Investigator

    R56DK050561     (HASKINS, KATHRYN M)Sep 1, 1996 - Aug 31, 2006
    NIH/NIDDK
    Effector Function of Autoreactive Th1 T Cells
    Role: Principal Investigator

    R01DK050561     (HASKINS, KATHRYN M)Sep 1, 1996 - Jun 30, 2011
    NIH/NIDDK
    Effector Function of Autoreactive Th1 T Cells
    Role: Principal Investigator

    R01AI044482     (HASKINS, KATHRYN)Sep 30, 1998 - Aug 31, 2001
    NIH/NIAID
    IMMUNOREGULATION IN THE NOD MOUSE
    Role: Principal Investigator

    R21AI065355     (HASKINS, KATHRYN M)Sep 30, 2004 - Sep 29, 2006
    NIH/NIAID
    Proteomics Analysis of T Cell Autoantigens in TID2
    Role: Principal Investigator

    R01DK081166     (HASKINS, KATHRYN M)Apr 1, 2011 - Mar 31, 2021
    NIH/NIDDK
    Hybrid Peptides as Autoantigens for Diabetogenic CD4 T Cells
    Role: Principal Investigator

    R21AR065340     (HASKINS, KATHRYN M)Apr 1, 2015 - Mar 31, 2017
    NIH/NIAMS
    Role of T Cells Specific for Citrullinated Fibrinogen in Rheumatoid Arthritis
    Role: Principal Investigator

    R21AI132907     (HASKINS, KATHRYN M)May 15, 2018 - Apr 30, 2020
    NIH/NIAID
    Autoantibodies to hybrid insulin peptides in type 1 diabetes
    Role: Principal Investigator

    R01DK122566     (HASKINS, KATHRYN M)Jun 15, 2019 - May 31, 2023
    NIH/NIDDK
    T cell repertoire for hybrid insulin peptides
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Baker RL, Rihanek M, Hohenstein AC, Nakayama M, Michels A, Gottlieb PA, Haskins K, Delong T. Hybrid Insulin Peptides are Autoantigens in Type 1 Diabetes. Diabetes. 2019 Jun 07. PMID: 31175101.
      View in: PubMed
    2. Baker RL, Jamison BL, Haskins K. Hybrid insulin peptides are neo-epitopes for CD4 T cells in autoimmune diabetes. Curr Opin Endocrinol Diabetes Obes. 2019 Jun 03. PMID: 31166225.
      View in: PubMed
    3. Jamison BL, Neef T, Goodspeed A, Bradley B, Baker RL, Miller SD, Haskins K. Nanoparticles Containing an Insulin-ChgA Hybrid Peptide Protect from Transfer of Autoimmune Diabetes by Shifting the Balance between Effector T Cells and Regulatory T Cells. J Immunol. 2019 Jul 01; 203(1):48-57. PMID: 31109955.
      View in: PubMed
    4. Sandor AM, Lindsay RS, Dyjack N, Whitesell JC, Rios C, Bradley BJ, Haskins K, Serreze DV, Geurts AM, Chen YG, Seibold MA, Jacobelli J, Friedman RS. CD11c+ Cells Are Gatekeepers for Lymphocyte Trafficking to Infiltrated Islets During Type 1 Diabetes. Front Immunol. 2019; 10:99. PMID: 30766536.
      View in: PubMed
    5. Aaron Wiles T, Powell R, Michel CR, Scott Beard K, Hohenstein A, Bradley B, Reisdorph N, Haskins K, Delong T. Identification of Hybrid Insulin Peptides (HIPs) in Mouse and Human Islets by Mass Spectrometry. J Proteome Res. 2019 Mar 01; 18(3):814-825. PMID: 30585061.
      View in: PubMed
    6. Jamison BL, Haskins K. Tissue Crosstalk in T1D: Is Insulin Special? Immunity. 2018 09 18; 49(3):394-396. PMID: 30231981.
      View in: PubMed
    7. Baker RL, Jamison BL, Wiles TA, Lindsay RS, Barbour G, Bradley B, Delong T, Friedman RS, Nakayama M, Haskins K. CD4 T Cells Reactive to Hybrid Insulin Peptides Are Indicators of Disease Activity in the NOD Mouse. Diabetes. 2018 09; 67(9):1836-1846. PMID: 29976617.
      View in: PubMed
    8. Babon JAB, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC. Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nat Med. 2017 08 04; 23(8):1004. PMID: 28777787.
      View in: PubMed
    9. Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC. Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nat Med. 2017 Feb 07; 23(2):264. PMID: 28170374.
      View in: PubMed
    10. Haskins K, Buckner JH. Editorial overview: Autoimmunity. Curr Opin Immunol. 2016 12; 43:v-vii. PMID: 27839940.
      View in: PubMed
    11. Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC. Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nat Med. 2016 12; 22(12):1482-1487. PMID: 27798614.
      View in: PubMed
    12. Wiles TA, Delong T, Baker RL, Bradley B, Barbour G, Powell RL, Reisdorph N, Haskins K. An insulin-IAPP hybrid peptide is an endogenous antigen for CD4 T cells in the non-obese diabetic mouse. J Autoimmun. 2017 03; 78:11-18. PMID: 27802879.
      View in: PubMed
    13. Delong T, Wiles TA, Baker RL, Bradley B, Barbour G, Reisdorph R, Armstrong M, Powell RL, Reisdorph N, Kumar N, Elso CM, DeNicola M, Bottino R, Powers AC, Harlan DM, Kent SC, Mannering SI, Haskins K. Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion. Science. 2016 Feb 12; 351(6274):711-4. PMID: 26912858.
      View in: PubMed
    14. Baker RL, Bradley B, Wiles TA, Lindsay RS, Barbour G, Delong T, Friedman RS, Haskins K. Cutting Edge: Nonobese Diabetic Mice Deficient in Chromogranin A Are Protected from Autoimmune Diabetes. J Immunol. 2016 Jan 01; 196(1):39-43. PMID: 26608914.
      View in: PubMed
    15. Viret C, Mahiddine K, Baker RL, Haskins K, Guerder S. The T Cell Repertoire-Diversifying Enzyme TSSP Contributes to Thymic Selection of Diabetogenic CD4 T Cell Specificities Reactive to ChgA and IAPP Autoantigens. J Immunol. 2015 Sep 01; 195(5):1964-73. PMID: 26209627.
      View in: PubMed
    16. Lindsay RS, Corbin K, Mahne A, Levitt BE, Gebert MJ, Wigton EJ, Bradley BJ, Haskins K, Jacobelli J, Tang Q, Krummel MF, Friedman RS. Antigen recognition in the islets changes with progression of autoimmune islet infiltration. J Immunol. 2015 Jan 15; 194(2):522-30. PMID: 25505281.
      View in: PubMed
    17. Nair KS, Abel ED, Adler SG, Dyck PJ, Gardner TW, Haskins KM, Hotamisligil G, Jensen MD, Krook A, Mandarino LJ, Mitchell BD, Pessin JE, Sowers JR, Sussel L, Wareham N, Vella A. Time to look back and to look forward. Diabetes. 2014 Apr; 63(4):1169-70. PMID: 24651796.
      View in: PubMed
    18. Gottlieb PA, Delong T, Baker RL, Fitzgerald-Miller L, Wagner R, Cook G, Rewers MR, Michels A, Haskins K. Chromogranin A is a T cell antigen in human type 1 diabetes. J Autoimmun. 2014 May; 50:38-41. PMID: 24239002.
      View in: PubMed
    19. Baker RL, Delong T, Barbour G, Bradley B, Nakayama M, Haskins K. Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic mice. J Immunol. 2013 Oct 15; 191(8):3990-4. PMID: 24043895.
      View in: PubMed
    20. Delong T, Baker RL, He J, Haskins K. Novel autoantigens for diabetogenic CD4 T cells in autoimmune diabetes. Immunol Res. 2013 Mar; 55(1-3):167-72. PMID: 22971988.
      View in: PubMed
    21. Cordova KN, Willis VC, Haskins K, Holers VM. A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis. J Immunol. 2013 Feb 15; 190(4):1457-65. PMID: 23319740.
      View in: PubMed
    22. Delong T, Baker RL, He J, Barbour G, Bradley B, Haskins K. Diabetogenic T-cell clones recognize an altered peptide of chromogranin A. Diabetes. 2012 Dec; 61(12):3239-46. PMID: 22912420.
      View in: PubMed
    23. Baker RL, Mallevaey T, Gapin L, Haskins K. T cells interact with T cells via CD40-CD154 to promote autoimmunity in type 1 diabetes. Eur J Immunol. 2012 Mar; 42(3):672-80. PMID: 22488364.
      View in: PubMed
    24. Hume PS, He J, Haskins K, Anseth KS. Strategies to reduce dendritic cell activation through functional biomaterial design. Biomaterials. 2012 May; 33(14):3615-25. PMID: 22361099.
      View in: PubMed
    25. Nakayama M, Castoe T, Sosinowski T, He X, Johnson K, Haskins K, Vignali DA, Gapin L, Pollock D, Eisenbarth GS. Germline TRAV5D-4 T-cell receptor sequence targets a primary insulin peptide of NOD mice. Diabetes. 2012 Apr; 61(4):857-65. PMID: 22315318.
      View in: PubMed
    26. Kyewski B, Haskins K. The classical dichotomy between presentation of endogenous antigens via the MHC class I pathway and exogenous antigens via the MHC class-II pathway. Curr Opin Immunol. 2012 Feb; 24(1):67-70. PMID: 22305303.
      View in: PubMed
    27. Haskins K, Cooke A. CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes. Curr Opin Immunol. 2011 Dec; 23(6):739-45. PMID: 21917439.
      View in: PubMed
    28. Delong T, Baker RL, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Barbour G, Bradley B, Haskins K. Islet amyloid polypeptide is a target antigen for diabetogenic CD4+ T cells. Diabetes. 2011 Sep; 60(9):2325-30. PMID: 21734016.
      View in: PubMed
    29. Zimmerman MA, Haskins K, Bradley B, Gilman J, Gamboni-Robertson F, Flores SC. Autoimmune-mediated vascular injury occurs prior to sustained hyperglycemia in a murine model of type I diabetes mellitus. J Surg Res. 2011 Jun 15; 168(2):e195-202. PMID: 21470634.
      View in: PubMed
    30. Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K. Chromogranin A is an autoantigen in type 1 diabetes. Nat Immunol. 2010 Mar; 11(3):225-31. PMID: 20139986.
      View in: PubMed
    31. Tonkin DR, Haskins K. Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner. Eur J Immunol. 2009 May; 39(5):1313-22. PMID: 19404982.
      View in: PubMed
    32. Zhang L, Jasinski JM, Kobayashi M, Davenport B, Johnson K, Davidson H, Nakayama M, Haskins K, Eisenbarth GS. Analysis of T cell receptor beta chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 alpha chains. J Autoimmun. 2009 Aug; 33(1):42-9. PMID: 19286348.
      View in: PubMed
    33. Baker RL, Wagner DH, Haskins K. CD40 on NOD CD4 T cells contributes to their activation and pathogenicity. J Autoimmun. 2008 Dec; 31(4):385-92. PMID: 18951762.
      View in: PubMed
    34. Tonkin DR, He J, Barbour G, Haskins K. Regulatory T cells prevent transfer of type 1 diabetes in NOD mice only when their antigen is present in vivo. J Immunol. 2008 Oct 01; 181(7):4516-22. PMID: 18802054.
      View in: PubMed
    35. Burton AR, Vincent E, Arnold PY, Lennon GP, Smeltzer M, Li CS, Haskins K, Hutton J, Tisch RM, Sercarz EE, Santamaria P, Workman CJ, Vignali DA. On the pathogenicity of autoantigen-specific T-cell receptors. Diabetes. 2008 May; 57(5):1321-30. PMID: 18299317.
      View in: PubMed
    36. He J, Haskins K. Pathogenicity of T helper 2 T-cell clones from T-cell receptor transgenic non-obese diabetic mice is determined by tumour necrosis factor-alpha. Immunology. 2008 Jan; 123(1):108-17. PMID: 17983440.
      View in: PubMed
    37. Cantor J, Haskins K. Recruitment and activation of macrophages by pathogenic CD4 T cells in type 1 diabetes: evidence for involvement of CCR8 and CCL1. J Immunol. 2007 Nov 01; 179(9):5760-7. PMID: 17947648.
      View in: PubMed
    38. Nicolls MR, Haskins K, Flores SC. Oxidant stress, immune dysregulation, and vascular function in type I diabetes. Antioxid Redox Signal. 2007 Jul; 9(7):879-89. PMID: 17508913.
      View in: PubMed
    39. Weber LM, Hayda KN, Haskins K, Anseth KS. The effects of cell-matrix interactions on encapsulated beta-cell function within hydrogels functionalized with matrix-derived adhesive peptides. Biomaterials. 2007 Jul; 28(19):3004-11. PMID: 17391752.
      View in: PubMed
    40. Quinn A, McInerney M, Huffman D, McInerney B, Mayo S, Haskins K, Sercarz E. T cells to a dominant epitope of GAD65 express a public CDR3 motif. Int Immunol. 2006 Jun; 18(6):967-79. PMID: 16641112.
      View in: PubMed
    41. Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983. J Immunol. 2006 Mar 01; 176(5):2683-90. PMID: 16493022.
      View in: PubMed
    42. Weber LM, He J, Bradley B, Haskins K, Anseth KS. PEG-based hydrogels as an in vitro encapsulation platform for testing controlled beta-cell microenvironments. Acta Biomater. 2006 Jan; 2(1):1-8. PMID: 16701853.
      View in: PubMed
    43. Phillips JM, Haskins K, Cooke A. MAdCAM-1 is needed for diabetes development mediated by the T cell clone, BDC-2.5. Immunology. 2005 Dec; 116(4):525-31. PMID: 16313366.
      View in: PubMed
    44. Cantor J, Haskins K. Effector function of diabetogenic CD4 Th1 T cell clones: a central role for TNF-alpha. J Immunol. 2005 Dec 01; 175(11):7738-45. PMID: 16301684.
      View in: PubMed
    45. Ling X, Cota-Gomez A, Flores NC, Hernandez-Saavedra D, McCord JM, Marecki JC, Haskins K, McDuffie M, Powers K, Kench J, Oka M, McMurtry I, Flores SC. Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice. Free Radic Biol Med. 2005 Oct 15; 39(8):1089-98. PMID: 16198235.
      View in: PubMed
    46. Haskins K. Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse. Adv Immunol. 2005; 87:123-62. PMID: 16102573.
      View in: PubMed
    47. Pauza ME, Dobbs CM, He J, Patterson T, Wagner S, Anobile BS, Bradley BJ, Lo D, Haskins K. T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes. Diabetes. 2004 Apr; 53(4):978-88. PMID: 15047613.
      View in: PubMed
    48. Haskins K. T-cell receptor transgenic (TCR-Tg) mice from two diabetogenic CD4+ islet-antigen-specific T-cell clones. J Autoimmun. 2004 Mar; 22(2):107-9. PMID: 14987737.
      View in: PubMed
    49. Haskins K, Kench J, Powers K, Bradley B, Pugazhenthi S, Reusch J, McDuffie M. Role for oxidative stress in the regeneration of islet beta cells? J Investig Med. 2004 Jan; 52(1):45-9. PMID: 14989369.
      View in: PubMed
    50. Haskins K, Bradley B, Powers K, Fadok V, Flores S, Ling X, Pugazhenthi S, Reusch J, Kench J. Oxidative stress in type 1 diabetes. Ann N Y Acad Sci. 2003 Nov; 1005:43-54. PMID: 14679039.
      View in: PubMed
    51. Stratmann T, Martin-Orozco N, Mallet-Designe V, Poirot L, McGavern D, Losyev G, Dobbs CM, Oldstone MB, Yoshida K, Kikutani H, Mathis D, Benoist C, Haskins K, Teyton L. Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity. J Clin Invest. 2003 Sep; 112(6):902-14. PMID: 12975475.
      View in: PubMed
    52. Roberts SA, Barbour G, Matarrese MR, Mason DL, Leiter EH, Haskins K, Hanson MS. Adoptive transfer of islet antigen-autoreactive T cell clones to transgenic NOD.Ea(d)mice induces diabetes indicating a lack of I-E mediated protection against activated effector T cells. J Autoimmun. 2003 Sep; 21(2):139-47. PMID: 12935783.
      View in: PubMed
    53. Vaitaitis GM, Poulin M, Sanderson RJ, Haskins K, Wagner DH. Cutting edge: CD40-induced expression of recombination activating gene (RAG) 1 and RAG2: a mechanism for the generation of autoaggressive T cells in the periphery. J Immunol. 2003 Apr 01; 170(7):3455-9. PMID: 12646605.
      View in: PubMed
    54. Yoshida K, Martin T, Yamamoto K, Dobbs C, Münz C, Kamikawaji N, Nakano N, Rammensee HG, Sasazuki T, Haskins K, Kikutani H. Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones. Int Immunol. 2002 Dec; 14(12):1439-47. PMID: 12456592.
      View in: PubMed
    55. Wagner DH, Vaitaitis G, Sanderson R, Poulin M, Dobbs C, Haskins K. Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3782-7. PMID: 11891296.
      View in: PubMed
    56. Piganelli JD, Flores SC, Cruz C, Koepp J, Batinic-Haberle I, Crapo J, Day B, Kachadourian R, Young R, Bradley B, Haskins K. A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone. Diabetes. 2002 Feb; 51(2):347-55. PMID: 11812741.
      View in: PubMed
    57. Kaufman DL, Tisch R, Sarvetnick N, Chatenoud L, Harrison LC, Haskins K, Quinn A, Sercarz E, Singh B, von Herrath M, Wegmann D, Wen L, Zekzer D. Report from the 1st International NOD Mouse T-Cell Workshop and the follow-up mini-workshop. Diabetes. 2001 Nov; 50(11):2459-63. PMID: 11679422.
      View in: PubMed
    58. Dobbs C, Haskins K. Comparison of a T cell clone and of T cells from a TCR transgenic mouse: TCR transgenic T cells specific for self-antigen are atypical. J Immunol. 2001 Feb 15; 166(4):2495-504. PMID: 11160310.
      View in: PubMed
    59. Haskins K, Atkinson M. Prediction of diabetes and response to therapy in individual animals: are there lessons for man? Report on the JDF/Snow Mountain Meeting, 5-7 October 2000, Winter Park, CO, USA. J Autoimmun. 2001 Feb; 16(1):15-9. PMID: 11221992.
      View in: PubMed
    60. Phillips JM, Harach SZ, Parish NM, Fehervari Z, Haskins K, Cooke A. Nondepleting anti-CD4 has an immediate action on diabetogenic effector cells, halting their destruction of pancreatic beta cells. J Immunol. 2000 Aug 15; 165(4):1949-55. PMID: 10925277.
      View in: PubMed
    61. Tree TI, O'Byrne D, Tremble JM, MacFarlane WM, Haskins K, James RF, Docherty K, Hutton JC, Banga JP. Evidence for recognition of novel islet T cell antigens by granule-specific T cell lines from new onset type 1 diabetic patients. Clin Exp Immunol. 2000 Jul; 121(1):100-5. PMID: 10886245.
      View in: PubMed
    62. Bergman B, McManaman JL, Haskins K. Biochemical characterization of a beta cell membrane fraction antigenic for autoreactive T cell clones. J Autoimmun. 2000 Jun; 14(4):343-51. PMID: 10882061.
      View in: PubMed
    63. Poulin M, Haskins K. Induction of diabetes in nonobese diabetic mice by Th2 T cell clones from a TCR transgenic mouse. J Immunol. 2000 Mar 15; 164(6):3072-8. PMID: 10706696.
      View in: PubMed
    64. Piganelli JD, Poulin M, Martin T, Allison JP, Haskins K. Cytotoxic T lymphocyte antigen 4 (CD152) regulates self-reactive T cells in BALB/c but not in the autoimmune NOD mouse. J Autoimmun. 2000 Mar; 14(2):123-31. PMID: 10677243.
      View in: PubMed
    65. Rosmalen JG, Martin T, Dobbs C, Voerman JS, Drexhage HA, Haskins K, Leenen PJ. Subsets of macrophages and dendritic cells in nonobese diabetic mouse pancreatic inflammatory infiltrates: correlation with the development of diabetes. Lab Invest. 2000 Jan; 80(1):23-30. PMID: 10652999.
      View in: PubMed
    66. Fossati G, Cooke A, Papafio RQ, Haskins K, Stockinger B. Triggering a second T cell receptor on diabetogenic T cells can prevent induction of diabetes. J Exp Med. 1999 Aug 16; 190(4):577-83. PMID: 10449528.
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    67. Zaccone P, Phillips J, Conget I, Gomis R, Haskins K, Minty A, Bendtzen K, Cooke A, Nicoletti F. Interleukin-13 prevents autoimmune diabetes in NOD mice. Diabetes. 1999 Aug; 48(8):1522-8. PMID: 10426368.
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    68. Haskins K. T cell receptor gene usage in autoimmune diabetes. Int Rev Immunol. 1999; 18(1-2):61-81. PMID: 10614739.
      View in: PubMed
    69. Peterson JD, Berg R, Piganelli JD, Poulin M, Haskins K. Analysis of leukocytes recruited to the pancreas by diabetogenic T cell clones. Cell Immunol. 1998 Nov 01; 189(2):92-8. PMID: 9790722.
      View in: PubMed
    70. Piganelli JD, Martin T, Haskins K. Splenic macrophages from the NOD mouse are defective in the ability to present antigen. Diabetes. 1998 Aug; 47(8):1212-8. PMID: 9703319.
      View in: PubMed
    71. McKeever U, Khandekar S, Jesson M, Newcomb J, Gregory P, Naylor J, Haskins K, Jones B. Maternal immunization with a soluble TCR-Ig chimeric protein: long term, V beta-8 family-specific suppression of T cells by maternally transferred antibodies. J Immunol. 1997 Dec 15; 159(12):5936-45. PMID: 9550391.
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    72. Bergman B, Haskins K. Autoreactive T-cell clones from the nonobese diabetic mouse. Proc Soc Exp Biol Med. 1997 Jan; 214(1):41-8. PMID: 9012359.
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    73. McKeever U, Khandekar S, Newcomb J, Naylor J, Gregory P, Brauer P, Jesson M, Bettencourt B, Burke E, Alderson A, Banerji J, Haskins K, Jones B. Immunization with soluble BDC 2.5 T cell receptor-immunoglobulin chimeric protein:antibody specificity and protection of nonobese diabetic mice against adoptive transfer of diabetes by maternal immunization. J Exp Med. 1996 Nov 01; 184(5):1755-68. PMID: 8920864.
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    74. Haskins K, Wegmann D. Diabetogenic T-cell clones. Diabetes. 1996 Oct; 45(10):1299-305. PMID: 8826963.
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    75. Peterson JD, Haskins K. Transfer of diabetes in the NOD-scid mouse by CD4 T-cell clones. Differential requirement for CD8 T-cells. Diabetes. 1996 Mar; 45(3):328-36. PMID: 8593938.
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    76. Peterson JD, Pike B, Dallas-Pedretti A, Haskins K. Induction of diabetes with islet-specific T-cell clones is age dependent. Immunology. 1995 Jul; 85(3):455-60. PMID: 7558135.
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    77. Dallas-Pedretti A, McDuffie M, Haskins K. A diabetes-associated T-cell autoantigen maps to a telomeric locus on mouse chromosome 6. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1386-90. PMID: 7877988.
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    78. Peterson JD, Pike B, McDuffie M, Haskins K. Islet-specific T cell clones transfer diabetes to nonobese diabetic (NOD) F1 mice. J Immunol. 1994 Sep 15; 153(6):2800-6. PMID: 8077683.
      View in: PubMed
    79. Bergman B, Haskins K. Islet-specific T-cell clones from the NOD mouse respond to beta-granule antigen. Diabetes. 1994 Feb; 43(2):197-203. PMID: 8288043.
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    80. Katz JD, Wang B, Haskins K, Benoist C, Mathis D. Following a diabetogenic T cell from genesis through pathogenesis. Cell. 1993 Sep 24; 74(6):1089-100. PMID: 8402882.
      View in: PubMed
    81. Gill RG, Haskins K. Molecular mechanisms underlying diabetes and other autoimmune diseases. Immunol Today. 1993 Feb; 14(2):49-51. PMID: 8095390.
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    82. Bradley BJ, Haskins K, La Rosa FG, Lafferty KJ. CD8 T cells are not required for islet destruction induced by a CD4+ islet-specific T-cell clone. Diabetes. 1992 Dec; 41(12):1603-8. PMID: 1446802.
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    83. Wegmann D, Norbury-Glaser M, Bergman B, Haskins K. High efficiency presentation of TNP-conjugated islet antigen to islet-specific T cells by a hybrid B cell line expressing TNP-specific surface Ig. J Immunol. 1992 Jul 01; 149(1):77-82. PMID: 1318906.
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    84. Candéias S, Katz J, Benoist C, Mathis D, Haskins K. Islet-specific T-cell clones from nonobese diabetic mice express heterogeneous T-cell receptors. Proc Natl Acad Sci U S A. 1991 Jul 15; 88(14):6167-70. PMID: 2068098.
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    85. Supon P, Stecha P, Haskins K. Anti-islet cell antibodies from NOD mice. Diabetes. 1990 Nov; 39(11):1366-72. PMID: 2227111.
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    86. Haskins K, McDuffie M. Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone. Science. 1990 Sep 21; 249(4975):1433-6. PMID: 2205920.
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    87. Bradley BJ, Wang YY, Lafferty KJ, Haskins K. In vivo activity of an islet-reactive T-cell clone. J Autoimmun. 1990 Aug; 3(4):449-56. PMID: 1977404.
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    88. Haskins K, Portas M, Bergman B, Lafferty K, Bradley B. Pancreatic islet-specific T-cell clones from nonobese diabetic mice. Proc Natl Acad Sci U S A. 1989 Oct; 86(20):8000-4. PMID: 2510155.
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    89. Böhme J, Haskins K, Stecha P, van Ewijk W, LeMeur M, Gerlinger P, Benoist C, Mathis D. Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant. Science. 1989 Jun 09; 244(4909):1179-83. PMID: 2499048.
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    90. Haskins K, Portas M, Bradley B, Wegmann D, Lafferty K. T-lymphocyte clone specific for pancreatic islet antigen. Diabetes. 1988 Oct; 37(10):1444-8. PMID: 2458291.
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    91. Haskins K. The T-cell receptor for antigen. Year Immunol. 1985; 74-9. PMID: 3879908.
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    92. Roehm N, Herron L, Cambier J, DiGuisto D, Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells. Cell. 1984 Sep; 38(2):577-84. PMID: 6331891.
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    93. Haskins K, Hannum C, White J, Roehm N, Kubo R, Kappler J, Marrack P. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J Exp Med. 1984 Aug 01; 160(2):452-71. PMID: 6206178.
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    94. Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. Annu Rev Immunol. 1984; 2:51-66. PMID: 6085752.
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    95. Marrack P, Shimonkevitz R, Hannum C, Haskins K, Kappler J. The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity. J Exp Med. 1983 Nov 01; 158(5):1635-46. PMID: 6195288.
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    96. Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell. 1983 Nov; 35(1):295-302. PMID: 6605199.
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    97. Kappler J, Kubo R, Haskins K, White J, Marrack P. The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas. Cell. 1983 Oct; 34(3):727-37. PMID: 6605198.
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    98. Haskins K, Kubo R, White J, Pigeon M, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J Exp Med. 1983 Apr 01; 157(4):1149-69. PMID: 6601175.
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    99. White J, Haskins KM, Marrack P, Kappler J. Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies. J Immunol. 1983 Mar; 130(3):1033-7. PMID: 6185566.
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    100. Marrack P, Hannum C, Harris M, Haskins K, Kubo R, Pigeon M, Shimonkevitz R, White J, Kappler J. Antigen-specific, major histocompatibility complex-restricted T cell receptors. Immunol Rev. 1983; 76:131-45. PMID: 6363275.
      View in: PubMed
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