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Clyde J Wright

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS

    Collapse Research 
    Collapse research activities and funding
    K08HL098562     (WRIGHT, CLYDE JASON)Apr 1, 2010 - Mar 31, 2015
    NIH/NHLBI
    The unique role of IkBa in modulating NF-kB activity in the newborn lung.
    Role: Principal Investigator

    R01HL132941     (WRIGHT, CLYDE JASON)Jan 1, 2017 - Nov 30, 2021
    NIH/NHLBI
    Role of hepatic IkBb-mediated sustained NFkB activation in neonatal lung injury and abnormal development
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Rozance PJ, Wright CJ. Preparing for the first breath: in the developing lung, maternal overnutrition takes center stage. J Physiol. 2017 Sep 19. PMID: 28925540.
      View in: PubMed
    2. McKenna S, Butler B, Jatana L, Ghosh S, Wright CJ. Inhibition of I?Bß/NF?B signaling prevents LPS-induced IL1ß expression without increasing apoptosis in the developing mouse lung. Pediatr Res. 2017 Aug 23. PMID: 28753596.
      View in: PubMed
    3. Sherlock LG, Wright CJ. Preventing extubation failure in preterm infants: nasal CPAP remains the standard of care. Acta Paediatr. 2017 Aug; 106(8):1364. PMID: 28370320.
      View in: PubMed
    4. Wright CJ, Norman M, Kirpalani H, Johansson S. EBNEO commentaries in Acta Paediatrica: a new collaboration to advance evidence-based neonatology. Acta Paediatr. 2017 Mar; 106(3):358. PMID: 28186374.
      View in: PubMed
    5. Wright CJ, Polin RA. Noninvasive Support: Does It Really Decrease Bronchopulmonary Dysplasia? Clin Perinatol. 2016 Dec; 43(4):783-798. PMID: 27837759.
      View in: PubMed
    6. Wright CJ, Kirpalani H. When should we start continuous positive airway pressure in the delivery room and how high should we go? Acta Paediatr. 2016 Aug; 105(8):868-70. PMID: 27383516.
      View in: PubMed
    7. McKenna S, Eckman M, Parker A, Bok R, Hurt KJ, Wright CJ. Perinatal Endotoxemia Induces Sustained Hepatic COX-2 Expression through an NF?B-Dependent Mechanism. J Innate Immun. 2016; 8(4):386-99. PMID: 27160391.
      View in: PubMed
    8. Wright CJ, Polin RA, Kirpalani H. Continuous Positive Airway Pressure to Prevent Neonatal Lung Injury: How Did We Get Here, and How Do We Improve? J Pediatr. 2016 Jun; 173:17-24.e2. PMID: 27025910.
      View in: PubMed
    9. McKenna S, Gossling M, Bugarini A, Hill E, Anderson AL, Rancourt RC, Balasubramaniyan N, El Kasmi KC, Wright CJ. Endotoxemia Induces I?Bß/NF-?B-Dependent Endothelin-1 Expression in Hepatic Macrophages. J Immunol. 2015 Oct 15; 195(8):3866-79. PMID: 26342031; PMCID: PMC4730915 [Available on 10/15/16].
    10. McKenna S, Wright CJ. Inhibiting I?Bß-NF?B signaling attenuates the expression of select pro-inflammatory genes. J Cell Sci. 2015 Jun 01; 128(11):2143-55. PMID: 25908863; PMCID: PMC4457027.
    11. Wright CJ, Permar SR. Preventing postnatal cytomegalovirus infection in the preterm infant: should it be done, can it be done, and at what cost? J Pediatr. 2015 Apr; 166(4):795-8. PMID: 25662832.
      View in: PubMed
    12. McKenna S, Michaelis KA, Agboke F, Liu T, Han K, Yang G, Dennery PA, Wright CJ. Sustained hyperoxia-induced NF-?B activation improves survival and preserves lung development in neonatal mice. Am J Physiol Lung Cell Mol Physiol. 2014 Jun 15; 306(12):L1078-89. PMID: 24748603; PMCID: PMC4060010.
    13. Michaelis KA, Agboke F, Liu T, Han K, Muthu M, Galambos C, Yang G, Dennery PA, Wright CJ. I?Bß-mediated NF-?B activation confers protection against hyperoxic lung injury. Am J Respir Cell Mol Biol. 2014 Feb; 50(2):429-38. PMID: 24066808; PMCID: PMC3930955.
    14. Stewart MS, Dietz RM, Landman MP, Moulton SL, Wright CJ. Abdominal radiograph with intravesical air and possible small bowel atresia. J Pediatr. 2014 May; 164(5):1238-1238.e1. PMID: 24472230.
      View in: PubMed
    15. Wright CJ, Saugstad OD. OHRP and SUPPORT: lessons in balancing safety and improving the way we care for patients. J Pediatr. 2013 Nov; 163(5):1495-7. PMID: 24050739.
      View in: PubMed
    16. Benjamin J, Wright CJ. Thin catheter surfactant administration during spontaneous breathing in very low birth weight infants is associated with reduced need for mechanical ventilation. J Pediatr. 2013 Sep; 163(3):923-4. PMID: 23973239.
      View in: PubMed
    17. Tang JR, Michaelis KA, Nozik-Grayck E, Seedorf GJ, Hartman-Filson M, Abman SH, Wright CJ. The NF-?B inhibitory proteins I?Ba and I?Bß mediate disparate responses to inflammation in fetal pulmonary endothelial cells. J Immunol. 2013 Mar 15; 190(6):2913-23. PMID: 23418625; PMCID: PMC3594141.
    18. Wright CJ. 50 Years ago in The Journal of Pediatrics: Some aspects of respiratory problems in the newborn: Cook CD. J Pediatric 1962;61:105-10. J Pediatr. 2012 Jul; 161(1):25. PMID: 22726322.
      View in: PubMed
    19. Wright CJ, Agboke F, Muthu M, Michaelis KA, Mundy MA, La P, Yang G, Dennery PA. Nuclear factor-?B (NF-?B) inhibitory protein I?Bß determines apoptotic cell death following exposure to oxidative stress. J Biol Chem. 2012 Feb 24; 287(9):6230-9. PMID: 22223647; PMCID: PMC3307281.
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