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Brian T Wimberly

TitleAsst Professor-Research
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BioChem&Molecular Genetics
Phone303/724-3256

    Collapse Research 
    Collapse research activities and funding
    R21AI149210     (RISSLAND, OLIVIA SELFRIDGE)Mar 1, 2020 - Feb 28, 2022
    NIH
    Mechanisms of protein production in the parasite Giardia Iamblia
    Role: Co-Principal Investigator
    F32GM015181     (WIMBERLY, BRIAN T)Feb 14, 1994
    NIH
    SOLUTION STRUCTURE OF A EUKARYOTIC RIBOSOMAL PROTEIN
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hartwick EW, Wimberly BT. Resolving Late-Stage Intermediates of Eukaryotic Ribosome Assembly. Structure. 2017 02 07; 25(2):216-218. PMID: 28178457.
      View in: PubMed
    2. Hussain T, Ll?cer JL, Wimberly BT, Kieft JS, Ramakrishnan V. Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation. Cell. 2016 Sep 22; 167(1):133-144.e13. PMID: 27662086.
      View in: PubMed
    3. Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW. Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell. 2014 Jul 03; 158(1):132-42. PMID: 24995984.
      View in: PubMed
    4. Wimberly BT. The use of ribosomal crystal structures in antibiotic drug design. Curr Opin Investig Drugs. 2009 Aug; 10(8):750-65. PMID: 19649920.
      View in: PubMed
    5. Brodersen DE, Clemons WM, Carter AP, Wimberly BT, Ramakrishnan V. Phasing the 30S ribosomal subunit structure. Acta Crystallogr D Biol Crystallogr. 2003 Nov; 59(Pt 11):2044-50. PMID: 14573961.
      View in: PubMed
    6. Brodersen DE, Clemons WM, Carter AP, Wimberly BT, Ramakrishnan V. Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 S RNA. J Mol Biol. 2002 Feb 22; 316(3):725-68. PMID: 11866529.
      View in: PubMed
    7. Clemons WM, Brodersen DE, McCutcheon JP, May JL, Carter AP, Morgan-Warren RJ, Wimberly BT, Ramakrishnan V. Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: purification, crystallization and structure determination. J Mol Biol. 2001 Jul 20; 310(4):827-43. PMID: 11453691.
      View in: PubMed
    8. Carter AP, Clemons WM, Brodersen DE, Morgan-Warren RJ, Hartsch T, Wimberly BT, Ramakrishnan V. Crystal structure of an initiation factor bound to the 30S ribosomal subunit. Science. 2001 Jan 19; 291(5503):498-501. PMID: 11228145.
      View in: PubMed
    9. Brodersen DE, Carter AP, Clemons WM, Morgan-Warren RJ, Murphy FV, Ogle JM, Tarry MJ, Wimberly BT, Ramakrishnan V. Atomic structures of the 30S subunit and its complexes with ligands and antibiotics. Cold Spring Harb Symp Quant Biol. 2001; 66:17-32. PMID: 12762005.
      View in: PubMed
    10. Brodersen DE, Clemons WM, Carter AP, Morgan-Warren RJ, Wimberly BT, Ramakrishnan V. The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell. 2000 Dec 22; 103(7):1143-54. PMID: 11163189.
      View in: PubMed
    11. Carter AP, Clemons WM, Brodersen DE, Morgan-Warren RJ, Wimberly BT, Ramakrishnan V. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature. 2000 Sep 21; 407(6802):340-8. PMID: 11014183.
      View in: PubMed
    12. Wimberly BT, Brodersen DE, Clemons WM, Morgan-Warren RJ, Carter AP, Vonrhein C, Hartsch T, Ramakrishnan V. Structure of the 30S ribosomal subunit. Nature. 2000 Sep 21; 407(6802):327-39. PMID: 11014182.
      View in: PubMed
    13. Allard P, Rak AV, Wimberly BT, Clemons WM, Kalinin A, Helgstrand M, Garber MB, Ramakrishnan V, H?rd T. Another piece of the ribosome: solution structure of S16 and its location in the 30S subunit. Structure. 2000 Aug 15; 8(8):875-82. PMID: 10997906.
      View in: PubMed
    14. Clemons WM, May JL, Wimberly BT, McCutcheon JP, Capel MS, Ramakrishnan V. Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution. Nature. 1999 Aug 26; 400(6747):833-40. PMID: 10476960.
      View in: PubMed
    15. Wimberly BT, Guymon R, McCutcheon JP, White SW, Ramakrishnan V. A detailed view of a ribosomal active site: the structure of the L11-RNA complex. Cell. 1999 May 14; 97(4):491-502. PMID: 10338213.
      View in: PubMed
    16. Wimberly BT, White SW, Ramakrishnan V. The structure of ribosomal protein S7 at 1.9 A resolution reveals a beta-hairpin motif that binds double-stranded nucleic acids. Structure. 1997 Sep 15; 5(9):1187-98. PMID: 9331418.
      View in: PubMed
    17. Wimberly B. A common RNA loop motif as a docking module and its function in the hammerhead ribozyme. Nat Struct Biol. 1994 Nov; 1(11):820-7. PMID: 7543360.
      View in: PubMed
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