Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Christina Mary Coughlan

TitleResearch Senior Instructor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-NEUR General Operations
Phone303/724-1348

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Coughlan C, Bruce KD, Burgy O, Boyd TD, Michel CR, Garcia-Perez JE, Adame V, Anton P, Bettcher BM, Chial HJ, Koenigshoff M, Hsieh EWY, Graner M, Potter H. Exosome Isolation by Ultracentrifugation and Precipitation and Techniques for Downstream Analyses. Curr Protoc Cell Biol. 2020 Sep; 88(1):e110. PMID: 32633898.
      View in: PubMed
    2. Bubak AN, Beseler C, Como CN, Coughlan CM, Johnson NR, Hassell JE, Burnet AM, Mescher T, Schmid DS, Coleman C, Mahalingam R, Cohrs RJ, Boyd TD, Potter H, Shilleh AH, Russ HA, Nagel MA. Amylin, Aß42, and Amyloid in VZV Vasculopathy Cerebrospinal Fluid and Infected Vascular Cells. J Infect Dis. 2020 Aug 18. PMID: 32809013.
      View in: PubMed
    3. Bubak AN, Como CN, Coughlan CM, Johnson NR, Hassell JE, Mescher T, Niemeyer CS, Mahalingam R, Cohrs RJ, Boyd TD, Potter H, Russ HA, Nagel MA. Varicella-Zoster Virus Infection of Primary Human Spinal Astrocytes Produces Intracellular Amylin, Amyloid-ß, and an Amyloidogenic Extracellular Environment. J Infect Dis. 2020 Mar 16; 221(7):1088-1097. PMID: 31665341.
      View in: PubMed
    4. Caneus J, Granic A, Rademakers R, Dickson DW, Coughlan CM, Chial HJ, Potter H. Mitotic defects lead to neuronal aneuploidy and apoptosis in frontotemporal lobar degeneration caused by MAPT mutations. Mol Biol Cell. 2018 03 01; 29(5):575-586. PMID: 29282277.
      View in: PubMed
    5. Boersma I, Jones J, Coughlan C, Carter J, Bekelman D, Miyasaki J, Kutner J, Kluger B. Palliative Care and Parkinson's Disease: Caregiver Perspectives. J Palliat Med. 2017 09; 20(9):930-938. PMID: 28520498.
      View in: PubMed
    6. Aivazidis S, Coughlan CM, Rauniyar AK, Jiang H, Liggett LA, Maclean KN, Roede JR. The burden of trisomy 21 disrupts the proteostasis network in Down syndrome. PLoS One. 2017; 12(4):e0176307. PMID: 28430800.
      View in: PubMed
    7. Coughlan C, Walker DI, Lohr KM, Richardson JR, Saba LM, Caudle WM, Fritz KS, Roede JR. Comparative Proteomic Analysis of Carbonylated Proteins from the Striatum and Cortex of Pesticide-Treated Mice. Parkinsons Dis. 2015; 2015:812532. PMID: 26345149.
      View in: PubMed
    8. Harris PS, Roy SR, Coughlan C, Orlicky DJ, Liang Y, Shearn CT, Roede JR, Fritz KS. Chronic ethanol consumption induces mitochondrial protein acetylation and oxidative stress in the kidney. Redox Biol. 2015 Dec; 6:33-40. PMID: 26177469.
      View in: PubMed
    9. Finlay-Schultz J, Canastar A, Short M, El Gazzar M, Coughlan C, Leonard S. Transcriptional repression of the a7 nicotinic acetylcholine receptor subunit gene (CHRNA7) by activating protein-2a (AP-2a). J Biol Chem. 2011 Dec 09; 286(49):42123-32. PMID: 21979958.
      View in: PubMed
    10. Falcone D, Henderson MP, Nieuwland H, Coughlan CM, Brodsky JL, Andrews DW. Stability and function of the Sec61 translocation complex depends on the Sss1p tail-anchor sequence. Biochem J. 2011 Jun 01; 436(2):291-303. PMID: 21355855.
      View in: PubMed
    11. Sparvero LJ, Patz S, Brodsky JL, Coughlan CM. Proteomic analysis of the amyloid precursor protein fragment C99: expression in yeast. Anal Biochem. 2007 Nov 15; 370(2):162-70. PMID: 17869211.
      View in: PubMed
    12. Coughlan CM, Brodsky JL. Use of yeast as a model system to investigate protein conformational diseases. Mol Biotechnol. 2005 Jun; 30(2):171-80. PMID: 15920289.
      View in: PubMed
    13. Coughlan CM, Walker JL, Cochran JC, Wittrup KD, Brodsky JL. Degradation of mutated bovine pancreatic trypsin inhibitor in the yeast vacuole suggests post-endoplasmic reticulum protein quality control. J Biol Chem. 2004 Apr 09; 279(15):15289-97. PMID: 14744871.
      View in: PubMed
    14. Chalasani SH, Baribaud F, Coughlan CM, Sunshine MJ, Lee VM, Doms RW, Littman DR, Raper JA. The chemokine stromal cell-derived factor-1 promotes the survival of embryonic retinal ganglion cells. J Neurosci. 2003 Jun 01; 23(11):4601-12. PMID: 12805300.
      View in: PubMed
    15. Coughlan CM, Brodsky JL. Yeast as a model system to investigate protein conformational diseases. Methods Mol Biol. 2003; 232:77-90. PMID: 12840541.
      View in: PubMed
    16. Puffer BA, Sharron M, Coughlan CM, Baribaud F, McManus CM, Lee B, David J, Price K, Horuk R, Tsang M, Doms RW. Expression and coreceptor function of APJ for primate immunodeficiency viruses. Virology. 2000 Oct 25; 276(2):435-44. PMID: 11040134.
      View in: PubMed
    17. Coughlan CM, Breen KC. Factors influencing the processing and function of the amyloid beta precursor protein--a potential therapeutic target in Alzheimer's disease? Pharmacol Ther. 2000 May; 86(2):111-45. PMID: 10799711.
      View in: PubMed
    18. Coughlan CM, McManus CM, Sharron M, Gao Z, Murphy D, Jaffer S, Choe W, Chen W, Hesselgesser J, Gaylord H, Kalyuzhny A, Lee VM, Wolf B, Doms RW, Kolson DL. Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons. Neuroscience. 2000; 97(3):591-600. PMID: 10828541.
      View in: PubMed
    19. Budas G, Coughlan CM, Seckl JR, Breen KC. The effect of corticosteroids on amyloid beta precursor protein/amyloid precursor-like protein expression and processing in vivo. Neurosci Lett. 1999 Nov 26; 276(1):61-4. PMID: 10586975.
      View in: PubMed
    20. McFarlane I, Georgopoulou N, Coughlan CM, Gillian AM, Breen KC. The role of the protein glycosylation state in the control of cellular transport of the amyloid beta precursor protein. Neuroscience. 1999 Apr; 90(1):15-25. PMID: 10188930.
      View in: PubMed
    21. Breen KC, Coughlan CM, Hayes FD. The role of glycoproteins in neural development function, and disease. Mol Neurobiol. 1998 Apr; 16(2):163-220. PMID: 9588627.
      View in: PubMed
    22. Coughlan CM, Breen KC. Glucocorticoid induction of the alpha2,6 sialyltransferase enzyme in a mouse neural cell line. J Neurosci Res. 1998 Mar 01; 51(5):619-26. PMID: 9512006.
      View in: PubMed
    23. Maguire TM, Coughlan CM, Seckl JR, Breen KC. The effect of corticosteroids on serum sialyltransferase enzyme activities in the rat. Biochim Biophys Acta. 1998 Jan 08; 1379(1):23-8. PMID: 9468328.
      View in: PubMed
    24. Coughlan CM, Burger PG, Berger EG, Breen KC. The biochemical consequences of alpha2,6(N) sialyltransferase induction by dexamethasone on sialoglycoprotein expression in the rat H411e hepatoma cell line. FEBS Lett. 1997 Aug 18; 413(2):389-93. PMID: 9280318.
      View in: PubMed
    25. Coughlan CM, Seckl JR, Breen KC. The expression of neural cell sialoglycoproteins following glucocorticoid regulation of sialyltransferase activity in vivo. Cell Mol Neurobiol. 1996 Jun; 16(3):433-8. PMID: 8818410.
      View in: PubMed
    26. Coughlan CM, Seckl JR, Fox DJ, Unsworth R, Breen KC. Tissue-specific regulation of sialyltransferase activities in the rat by corticosteroids in vivo. Glycobiology. 1996 Jan; 6(1):15-22. PMID: 8991504.
      View in: PubMed
    27. Coughlan CM, Breen KC. The control of sialyltransferase activity in tumor-cell lines derived from different tissues in multifactorial. FEBS Lett. 1995 Aug 07; 369(2-3):260-2. PMID: 7649268.
      View in: PubMed
    28. Maguire TM, Gillian AM, O'Mahony D, Coughlan CM, Dennihan A, Breen KC. A decrease in serum sialyltransferase levels in Alzheimer's disease. Neurobiol Aging. 1994 Jan-Feb; 15(1):99-102. PMID: 8159268.
      View in: PubMed
    Coughlan's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description

    Copyright © 2020 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)