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Christina Mary Coughlan

TitleResearch Senior Instructor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Neurology
Phone303/724-1348

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Caneus J, Granic A, Rademakers R, Dickson DW, Coughlan CM, Chial HJ, Potter H. Mitotic defects lead to neuronal aneuploidy and apoptosis in frontotemporal lobar degeneration caused by MAPT mutations. Mol Biol Cell. 2018 Mar 01; 29(5):575-586. PMID: 29282277.
      View in: PubMed
    2. Boersma I, Jones J, Coughlan C, Carter J, Bekelman D, Miyasaki J, Kutner J, Kluger B. Palliative Care and Parkinson's Disease: Caregiver Perspectives. J Palliat Med. 2017 Sep; 20(9):930-938. PMID: 28520498.
      View in: PubMed
    3. Aivazidis S, Coughlan CM, Rauniyar AK, Jiang H, Liggett LA, Maclean KN, Roede JR. The burden of trisomy 21 disrupts the proteostasis network in Down syndrome. PLoS One. 2017; 12(4):e0176307. PMID: 28430800.
      View in: PubMed
    4. Coughlan C, Walker DI, Lohr KM, Richardson JR, Saba LM, Caudle WM, Fritz KS, Roede JR. Comparative Proteomic Analysis of Carbonylated Proteins from the Striatum and Cortex of Pesticide-Treated Mice. Parkinsons Dis. 2015; 2015:812532. PMID: 26345149; PMCID: PMC4546751.
      View in: PubMed, PubMed Central
    5. Harris PS, Roy SR, Coughlan C, Orlicky DJ, Liang Y, Shearn CT, Roede JR, Fritz KS. Chronic ethanol consumption induces mitochondrial protein acetylation and oxidative stress in the kidney. Redox Biol. 2015 Dec; 6:33-40. PMID: 26177469; PMCID: PMC4511634.
      View in: PubMed, PubMed Central
    6. Finlay-Schultz J, Canastar A, Short M, El Gazzar M, Coughlan C, Leonard S. Transcriptional repression of the a7 nicotinic acetylcholine receptor subunit gene (CHRNA7) by activating protein-2a (AP-2a). J Biol Chem. 2011 Dec 09; 286(49):42123-32. PMID: 21979958; PMCID: PMC3234925.
      View in: PubMed, PubMed Central
    7. Sparvero LJ, Patz S, Brodsky JL, Coughlan CM. Proteomic analysis of the amyloid precursor protein fragment C99: expression in yeast. Anal Biochem. 2007 Nov 15; 370(2):162-70. PMID: 17869211; PMCID: PMC2220045.
      View in: PubMed, PubMed Central
    8. Coughlan CM, Brodsky JL. Use of yeast as a model system to investigate protein conformational diseases. Mol Biotechnol. 2005 Jun; 30(2):171-80. PMID: 15920289.
      View in: PubMed
    9. Coughlan CM, Walker JL, Cochran JC, Wittrup KD, Brodsky JL. Degradation of mutated bovine pancreatic trypsin inhibitor in the yeast vacuole suggests post-endoplasmic reticulum protein quality control. J Biol Chem. 2004 Apr 09; 279(15):15289-97. PMID: 14744871.
      View in: PubMed
    10. Coughlan CM, Brodsky JL. Yeast as a model system to investigate protein conformational diseases. Methods Mol Biol. 2003; 232:77-90. PMID: 12840541.
      View in: PubMed
    11. Coughlan CM, Breen KC. Factors influencing the processing and function of the amyloid beta precursor protein--a potential therapeutic target in Alzheimer's disease? Pharmacol Ther. 2000 May; 86(2):111-45. PMID: 10799711.
      View in: PubMed
    12. Budas G, Coughlan CM, Seckl JR, Breen KC. The effect of corticosteroids on amyloid beta precursor protein/amyloid precursor-like protein expression and processing in vivo. Neurosci Lett. 1999 Nov 26; 276(1):61-4. PMID: 10586975.
      View in: PubMed
    13. McFarlane I, Georgopoulou N, Coughlan CM, Gillian AM, Breen KC. The role of the protein glycosylation state in the control of cellular transport of the amyloid beta precursor protein. Neuroscience. 1999 Apr; 90(1):15-25. PMID: 10188930.
      View in: PubMed
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