Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Kirk Hansen

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BioChem&Molecular Genetics
Phone303/724-5544

    Collapse Research 
    Collapse research activities and funding
    S10RR023015     (HANSEN, KIRK C)May 1, 2007 - Apr 30, 2008
    NIH/NCRR
    LTQ FT-ICR Hybrid Mass Spectrometer Purchase
    Role: Principal Investigator

    S10RR024599     (HANSEN, KIRK C)Apr 1, 2009 - Mar 31, 2010
    NIH/NCRR
    LTQ Orbitrap Mass Spectrometer Request
    Role: Principal Investigator

    R21CA132741     (HANSEN, KIRK C)Sep 1, 2010 - Aug 31, 2013
    NIH/NCI
    Methods for the Analysis of Tumor Extracellular Matrix
    Role: Principal Investigator

    R33CA183685     (HANSEN, KIRK C)May 2, 2014 - Apr 30, 2017
    NIH/NCI
    Advanced Methods to Evaluate Extracellular Matrix and Crosslinking in the Tumor M
    Role: Principal Investigator

    S10OD021641     (HANSEN, KIRK C)May 15, 2017 - May 14, 2018
    NIH
    Quadrupole-Orbitrap Mass Spectrometer
    Role: Principal Investigator

    R43CA239872     (VRLJIC, MARIJA)Mar 11, 2019 - Feb 29, 2020
    NIH/NCI
    Development of a universal prodrug approach for antibody based therapeutics
    Role: Co-Principal Investigator

    RM1GM131968     (SILLIMAN, CHRISTOPHER C.)May 20, 2019 - Apr 30, 2024
    NIH/NIGMS
    Resuscitation Strategies for Achieving Thrombo-inflammatory Homeostasis
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Issaian A, Schmitt L, Born A, Nichols PJ, Sikela J, Hansen K, Vögeli B, Henen MA. Solution NMR backbone assignment reveals interaction-free tumbling of human lineage-specific Olduvai protein domains. Biomol NMR Assign. 2019 Jul 01. PMID: 31264103.
      View in: PubMed
    2. Morrison EJ, Champagne DP, Dzieciatkowska M, Nemkov T, Zimring JC, Hansen KC, Guan F, Huffman DM, Santambrogio L, D'Alessandro A. Parabiosis Incompletely Reverses Aging-Induced Metabolic Changes and Oxidant Stress in Mouse Red Blood Cells. Nutrients. 2019 Jun 14; 11(6). PMID: 31207887.
      View in: PubMed
    3. D'Alessandro A, Hansen KC, Eisenmesser EZ, Zimring JC. Protect, repair, destroy or sacrifice: a role of oxidative stress biology in inter-donor variability of blood storage? Blood Transfus. 2019 Jun 06; 1-8. PMID: 31184577.
      View in: PubMed
    4. Schmitt LR, Henderson R, Barrett A, Darula Z, Issaian A, D'Alessandro A, Clendenen N, Hansen KC. Mass spectrometry-based molecular mapping of native FXIIIa cross-links in insoluble fibrin clots. J Biol Chem. 2019 May 31; 294(22):8773-8778. PMID: 31028172.
      View in: PubMed
    5. Samuels J, Lawson PJ, Morton AP, Moore HB, Hansen KC, Sauaia A, Schoen JA. Prospective assessment of fibrinolysis in morbid obesity: tissue plasminogen activator resistance improves after bariatric surgery. Surg Obes Relat Dis. 2019 Apr 10. PMID: 31128997.
      View in: PubMed
    6. Lennon S, Oweida A, Milner D, Phan AV, Bhatia S, Van Court B, Darragh L, Mueller AC, Raben D, Martínez-Torrecuadrada JL, Pitts TM, Somerset H, Jordan KR, Hansen KC, Williams J, Messersmith WA, Schulick RD, Owens P, Goodman KA, Karam SD. Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination. Clin Cancer Res. 2019 Jun 01; 25(11):3352-3365. PMID: 30944125.
      View in: PubMed
    7. Gregory MA, Nemkov T, Park HJ, Zaberezhnyy V, Gehrke S, Adane B, Jordan CT, Hansen KC, D'Alessandro A, DeGregori J. Targeting Glutamine Metabolism and Redox State for Leukemia Therapy. Clin Cancer Res. 2019 Apr 02. PMID: 30940653.
      View in: PubMed
    8. Moore HB, Moore EE, Chapman MP, Hansen KC, Cohen MJ, Pieracci FM, Chandler J, Sauaia A. Does Tranexamic Acid Improve Clot Strength in Severely Injured Patients Who Have Elevated Fibrin Degradation Products and Low Fibrinolytic Activity, Measured by Thrombelastography? J Am Coll Surg. 2019 Mar 29. PMID: 30936005.
      View in: PubMed
    9. Dempsey SG, Miller CH, Hill RC, Hansen KC, May BCH. Functional Insights from the Proteomic Inventory of Ovine Forestomach Matrix. J Proteome Res. 2019 Apr 05; 18(4):1657-1668. PMID: 30879303.
      View in: PubMed
    10. Gehrke S, Rice S, Stefanoni D, Wilkerson RB, Nemkov T, Reisz JA, Hansen KC, Lucas A, Cabrales P, Drew K, D'Alessandro A. Red Blood Cell Metabolic Responses to Torpor and Arousal in the Hibernator Arctic Ground Squirrel. J Proteome Res. 2019 Apr 05; 18(4):1827-1841. PMID: 30793910.
      View in: PubMed
    11. Moore HB, D'alessandro A, Moore EE, Wither M, Lawson PJ, Huebner BR, Hansen K, Choudhury R, Nydam TL. Increase in post-reperfusion sensitivity to tissue plasminogen activator-mediated fibrinolysis during liver transplantation is associated with abnormal metabolic changes and increased blood product utilisation. Blood Transfus. 2019 Feb 04; 1-9. PMID: 30747704.
      View in: PubMed
    12. Carlson P, Dasgupta A, Grzelak CA, Kim J, Barrett A, Coleman IM, Shor RE, Goddard ET, Dai J, Schweitzer EM, Lim AR, Crist SB, Cheresh DA, Nelson PS, Hansen KC, Ghajar CM. Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy. Nat Cell Biol. 2019 02; 21(2):238-250. PMID: 30664790.
      View in: PubMed
    13. Nemkov T, Reisz JA, Gehrke S, Hansen KC, D'Alessandro A. High-Throughput Metabolomics: Isocratic and Gradient Mass Spectrometry-Based Methods. Methods Mol Biol. 2019; 1978:13-26. PMID: 31119654.
      View in: PubMed
    14. Clendenen N, Nunns GR, Moore EE, Gonzalez E, Chapman M, Reisz JA, Peltz E, Fragoso M, Nemkov T, Wither MJ, Sauaia A, Silliman CC, Hansen K, Banerjee A, D'alessandro A, Moore HB. Selective organ ischaemia/reperfusion identifies liver as the key driver of the post-injury plasma metabolome derangements. Blood Transfus. 2018 Dec 13; 1-13. PMID: 30747701.
      View in: PubMed
    15. Gaetani R, Aouad S, Demaddalena LL, Straessle H, Dzieciatkowska M, Wortham M, Bender HR, Nguyen-Ngoc KV, Schmid-Schoenbein GW, George SC, Hughes CCW, Sander M, Hansen KC, Christman KL. Evaluation of different decellularization protocols on the generation of pancreas-derived hydrogels. Tissue Eng Part C Methods. 2018 Nov 06. PMID: 30398401.
      View in: PubMed
    16. Reisz JA, Nemkov T, Dzieciatkowska M, Culp-Hill R, Stefanoni D, Hill RC, Yoshida T, Dunham A, Kanias T, Dumont LJ, Busch M, Eisenmesser EZ, Zimring JC, Hansen KC, D'Alessandro A. Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells. Transfusion. 2018 12; 58(12):2978-2991. PMID: 30312994.
      View in: PubMed
    17. Balas MM, Porman AM, Hansen KC, Johnson AM. SILAC-MS Profiling of Reconstituted Human Chromatin Platforms for the Study of Transcription and RNA Regulation. J Proteome Res. 2018 10 05; 17(10):3475-3484. PMID: 30192551.
      View in: PubMed
    18. Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM. A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma. Nat Cell Biol. 2018 10; 20(10):1203-1214. PMID: 30202050.
      View in: PubMed
    19. Loi MM, Kelher M, Dzieciatkowska M, Hansen KC, Banerjee A, West FB, Stanley C, Briel M, Silliman CC. A comparison of different methods of red blood cell leukoreduction and additive solutions on the accumulation of neutrophil-priming activity during storage. Transfusion. 2018 08; 58(8):2003-2012. PMID: 30171813.
      View in: PubMed
    20. Tomko LA, Hill RC, Barrett A, Szulczewski JM, Conklin MW, Eliceiri KW, Keely PJ, Hansen KC, Ponik SM. Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma. Sci Rep. 2018 Aug 28; 8(1):12941. PMID: 30154546.
      View in: PubMed
    21. Clement CC, Wang W, Dzieciatkowska M, Cortese M, Hansen KC, Becerra A, Thangaswamy S, Nizamutdinova I, Moon JY, Stern LJ, Gashev AA, Zawieja D, Santambrogio L. Quantitative Profiling of the Lymph Node Clearance Capacity. Sci Rep. 2018 Jul 26; 8(1):11253. PMID: 30050160.
      View in: PubMed
    22. Paukovich N, Xue M, Elder JR, Redzic JS, Blue A, Pike H, Miller BG, Pitts TM, Pollock DD, Hansen K, D'Alessandro A, Eisenmesser EZ. Biliverdin Reductase B Dynamics Are Coupled to Coenzyme Binding. J Mol Biol. 2018 Sep 14; 430(18 Pt B):3234-3250. PMID: 29932944.
      View in: PubMed
    23. Banerjee A, Silliman CC, Moore EE, Dzieciatkowska M, Kelher M, Sauaia A, Jones K, Chapman MP, Gonzalez E, Moore HB, D'Alessandro A, Peltz E, Huebner BE, Einerson P, Chandler J, Ghasabayan A, Hansen K. Systemic hyperfibrinolysis after trauma: a pilot study of targeted proteomic analysis of superposed mechanisms in patient plasma. J Trauma Acute Care Surg. 2018 06; 84(6):929-938. PMID: 29554044.
      View in: PubMed
    24. Faulds KJ, Egelston JN, Sedivy LJ, Mitchell MK, Garimella S, Kozlowski H, D'Alessandro A, Hansen KC, Balsbaugh JL, Phiel CJ. Glycogen synthase kinase-3 (GSK-3) activity regulates mRNA methylation in mouse embryonic stem cells. J Biol Chem. 2018 07 06; 293(27):10731-10743. PMID: 29777057.
      View in: PubMed
    25. Slaughter AL, Nunns GR, D'Alessandro A, Banerjee A, Hansen KC, Moore EE, Silliman CC, Nemkov T, Moore HB, Fragoso M, Leasia K, Peltz ED. The Metabolopathy of Tissue Injury, Hemorrhagic Shock, and Resuscitation in a Rat Model. Shock. 2018 05; 49(5):580-590. PMID: 28727610.
      View in: PubMed
    26. Li X, Liu S, Jiang J, Zhang L, Espinosa S, Hill RC, Hansen KC, Zhou ZH, Zhao R. Author Correction: CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing. Nat Commun. 2018 04 11; 9(1):1495. PMID: 29643343.
      View in: PubMed
    27. Reisz JA, Barrett AS, Nemkov T, Hansen KC, D'Alessandro A. When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies. Expert Rev Proteomics. 2018 04; 15(4):293-309. PMID: 29540077.
      View in: PubMed
    28. Wysoczynski-Horita CL, Boursier ME, Hill R, Hansen K, Blackwell HE, Churchill MEA. Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands. Mol Microbiol. 2018 05; 108(3):240-257. PMID: 29437248.
      View in: PubMed
    29. Zhou Y, Horowitz JC, Naba A, Ambalavanan N, Atabai K, Balestrini J, Bitterman PB, Corley RA, Ding BS, Engler AJ, Hansen KC, Hagood JS, Kheradmand F, Lin QS, Neptune E, Niklason L, Ortiz LA, Parks WC, Tschumperlin DJ, White ES, Chapman HA, Thannickal VJ. Extracellular matrix in lung development, homeostasis and disease. Matrix Biol. 2018 11; 73:77-104. PMID: 29524630.
      View in: PubMed
    30. Hazegh KE, Nemkov T, D'Alessandro A, Diller JD, Monks J, McManaman JL, Jones KL, Hansen KC, Reis T. Correction: An autonomous metabolic role for Spen. PLoS Genet. 2018 03; 14(3):e1007266. PMID: 29509756.
      View in: PubMed
    31. Reisz JA, Wither MJ, Moore EE, Slaughter AL, Moore HB, Ghasabyan A, Chandler J, Schaub LJ, Fragoso M, Nunns G, Silliman CC, Hansen KC, Banerjee A, Sheppard FR, D'Alessandro A. All animals are equal but some animals are more equal than others: Plasma lactate and succinate in hemorrhagic shock-A comparison in rodents, swine, nonhuman primates, and injured patients. J Trauma Acute Care Surg. 2018 03; 84(3):537-541. PMID: 29112093.
      View in: PubMed
    32. Culp-Hill R, Zheng C, Reisz JA, Smith K, Rachubinski A, Nemkov T, Butcher E, Granrath R, Hansen KC, Espinosa JM, D'Alessandro A. Red blood cell metabolism in Down syndrome: hints on metabolic derangements in aging. Blood Adv. 2017 Dec 26; 1(27):2776-2780. PMID: 29296929.
      View in: PubMed
    33. Culp-Hill R, Reisz JA, Hansen KC, D'Alessandro A. Investigation of the effects of storage and freezing on mixes of heavy-labeled metabolite and amino acid standards. Rapid Commun Mass Spectrom. 2017 Dec 15; 31(23):2030-2034. PMID: 28910859.
      View in: PubMed
    34. Moore HB, Moore EE, Huebner BR, Dzieciatkowska M, Stettler GR, Nunns GR, Lawson PJ, Ghasabyan A, Chandler J, Banerjee A, Silliman C, Sauaia A, Hansen KC. Fibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activator. J Trauma Acute Care Surg. 2017 12; 83(6):1014-1022. PMID: 29190254.
      View in: PubMed
    35. Liu S, Li X, Zhang L, Jiang J, Hill RC, Cui Y, Hansen KC, Zhou ZH, Zhao R. Structure of the yeast spliceosomal postcatalytic P complex. Science. 2017 12 08; 358(6368):1278-1283. PMID: 29146870.
      View in: PubMed
    36. Sun K, D'Alessandro A, Ahmed MH, Zhang Y, Song A, Ko TP, Nemkov T, Reisz JA, Wu H, Adebiyi M, Peng Z, Gong J, Liu H, Huang A, Wen YE, Wen AQ, Berka V, Bogdanov MV, Abdulmalik O, Han L, Tsai AL, Idowu M, Juneja HS, Kellems RE, Dowhan W, Hansen KC, Safo MK, Xia Y. Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease. Sci Rep. 2017 11 10; 7(1):15281. PMID: 29127281.
      View in: PubMed
    37. Barrett AS, Wither MJ, Hill RC, Dzieciatkowska M, D'Alessandro A, Reisz JA, Hansen KC. Hydroxylamine Chemical Digestion for Insoluble Extracellular Matrix Characterization. J Proteome Res. 2017 11 03; 16(11):4177-4184. PMID: 28971683.
      View in: PubMed
    38. Nemkov T, Sun K, Reisz JA, Song A, Yoshida T, Dunham A, Wither MJ, Francis RO, Roach RC, Dzieciatkowska M, Rogers SC, Doctor A, Kriebardis A, Antonelou M, Papassideri I, Young CT, Thomas TA, Hansen KC, Spitalnik SL, Xia Y, Zimring JC, Hod EA, D'Alessandro A. Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage. Haematologica. 2018 02; 103(2):361-372. PMID: 29079593.
      View in: PubMed
    39. Li X, Liu S, Jiang J, Zhang L, Espinosa S, Hill RC, Hansen KC, Zhou ZH, Zhao R. CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing. Nat Commun. 2017 10 19; 8(1):1035. PMID: 29051543.
      View in: PubMed
    40. Nemkov T, Sun K, Reisz JA, Yoshida T, Dunham A, Wen EY, Wen AQ, Roach RC, Hansen KC, Xia Y, D'Alessandro A. Metabolism of Citrate and Other Carboxylic Acids in Erythrocytes As a Function of Oxygen Saturation and Refrigerated Storage. Front Med (Lausanne). 2017; 4:175. PMID: 29090212.
      View in: PubMed
    41. Clendenen N, Nunns GR, Moore EE, Reisz JA, Gonzalez E, Peltz E, Silliman CC, Fragoso M, Nemkov T, Wither MJ, Hansen K, Banerjee A, Moore HB, D'Alessandro A. Hemorrhagic shock and tissue injury drive distinct plasma metabolome derangements in swine. J Trauma Acute Care Surg. 2017 10; 83(4):635-642. PMID: 28463938.
      View in: PubMed
    42. Gregory MA, Nemkov T, Reisz JA, Zaberezhnyy V, Hansen KC, D'Alessandro A, DeGregori J. Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia. Exp Hematol. 2018 02; 58:52-58. PMID: 28947392.
      View in: PubMed
    43. Gehrke S, Reisz JA, Nemkov T, Hansen KC, D'Alessandro A. Characterization of rapid extraction protocols for high-throughput metabolomics. Rapid Commun Mass Spectrom. 2017 Sep 15; 31(17):1445-1452. PMID: 28586533.
      View in: PubMed
    44. Henry CJ, Nemkov T, Casás-Selves M, Bilousova G, Zaberezhnyy V, Higa KC, Serkova NJ, Hansen KC, D'Alessandro A, DeGregori J. Folate dietary insufficiency and folic acid supplementation similarly impair metabolism and compromise hematopoiesis. Haematologica. 2017 12; 102(12):1985-1994. PMID: 28883079.
      View in: PubMed
    45. D'Alessandro A, Moore HB, Moore EE, Reisz JA, Wither MJ, Ghasasbyan A, Chandler J, Silliman CC, Hansen KC, Banerjee A. Plasma succinate is a predictor of mortality in critically injured patients. J Trauma Acute Care Surg. 2017 09; 83(3):491-495. PMID: 28590356.
      View in: PubMed
    46. Liu H, Wang C, Lee S, Deng Y, Wither M, Oh S, Ning F, Dege C, Zhang Q, Liu X, Johnson AM, Zang J, Chen Z, Janknecht R, Hansen K, Marrack P, Li CY, Kappler JW, Hagman J, Zhang G. Clipping of arginine-methylated histone tails by JMJD5 and JMJD7. Proc Natl Acad Sci U S A. 2017 09 12; 114(37):E7717-E7726. PMID: 28847961.
      View in: PubMed
    47. Hazegh KE, Nemkov T, D'Alessandro A, Diller JD, Monks J, McManaman JL, Jones KL, Hansen KC, Reis T. An autonomous metabolic role for Spen. PLoS Genet. 2017 Jun; 13(6):e1006859. PMID: 28640815.
      View in: PubMed
    48. Sun K, Liu H, Song A, Manalo JM, D'Alessandro A, Hansen KC, Kellems RE, Eltzschig HK, Blackburn MR, Roach RC, Xia Y. Erythrocyte purinergic signaling components underlie hypoxia adaptation. J Appl Physiol (1985). 2017 Oct 01; 123(4):951-956. PMID: 28572494.
      View in: PubMed
    49. Huebner BR, Moore EE, Moore HB, Sauaia A, Stettler G, Dzieciatkowska M, Hansen K, Banerjee A, Silliman CC. Freeze-dried plasma enhances clot formation and inhibits fibrinolysis in the presence of tissue plasminogen activator similar to pooled liquid plasma. Transfusion. 2017 08; 57(8):2007-2015. PMID: 28500652.
      View in: PubMed
    50. Nemkov T, Hansen KC, D'Alessandro A. A three-minute method for high-throughput quantitative metabolomics and quantitative tracing experiments of central carbon and nitrogen pathways. Rapid Commun Mass Spectrom. 2017 Apr 30; 31(8):663-673. PMID: 28195377.
      View in: PubMed
    51. Heischmann S, Dzieciatkowska M, Hansen K, Leibfritz D, Christians U. The Immunosuppressant Mycophenolic Acid Alters Nucleotide and Lipid Metabolism in an Intestinal Cell Model. Sci Rep. 2017 03 22; 7:45088. PMID: 28327659.
      View in: PubMed
    52. D'Alessandro A, Gray AD, Szczepiorkowski ZM, Hansen K, Herschel LH, Dumont LJ. Red blood cell metabolic responses to refrigerated storage, rejuvenation, and frozen storage. Transfusion. 2017 04; 57(4):1019-1030. PMID: 28295356.
      View in: PubMed
    53. Clendenen N, Tollefson A, Dzieciatkowska M, Cambiaghi A, Ferrario M, Kroehl M, Banerjee A, D'Alessandro A, Hansen KC, Weitzel N. Correlation of pre-operative plasma protein concentrations in cardiac surgery patients with bleeding outcomes using a targeted quantitative proteomics approach. Proteomics Clin Appl. 2017 07; 11(7-8). PMID: 28176468.
      View in: PubMed
    54. D'alessandro A, Nemkov T, Reisz J, Dzieciatkowska M, Wither MJ, Hansen KC. Omics markers of the red cell storage lesion and metabolic linkage. Blood Transfus. 2017 Mar; 15(2):137-144. PMID: 28263171.
      View in: PubMed
    55. D'Alessandro A, Dzieciatkowska M, Nemkov T, Hansen KC. Red blood cell proteomics update: is there more to discover? Blood Transfus. 2017 03; 15(2):182-187. PMID: 28263177.
      View in: PubMed
    56. Cavalli G, Justice JN, Boyle KE, D'Alessandro A, Eisenmesser EZ, Herrera JJ, Hansen KC, Nemkov T, Stienstra R, Garlanda C, Mantovani A, Seals DR, Dagna L, Joosten LA, Ballak DB, Dinarello CA. Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance. Proc Natl Acad Sci U S A. 2017 02 28; 114(9):2313-2318. PMID: 28193888.
      View in: PubMed
    57. Song A, Zhang Y, Han L, Yegutkin GG, Liu H, Sun K, D'Alessandro A, Li J, Karmouty-Quintana H, Iriyama T, Weng T, Zhao S, Wang W, Wu H, Nemkov T, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Hansen KC, Zhang H, Bogdanov M, Dowhan W, Jin J, Kellems RE, Eltzschig HK, Blackburn M, Roach RC, Xia Y. Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent. Nat Commun. 2017 02 07; 8:14108. PMID: 28169986.
      View in: PubMed
    58. Kendrick AA, Schafer J, Dzieciatkowska M, Nemkov T, D'Alessandro A, Neelakantan D, Ford HL, Pearson CG, Weekes CD, Hansen KC, Eisenmesser EZ. CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming. Oncotarget. 2017 Jan 24; 8(4):6742-6762. PMID: 28039486.
      View in: PubMed
    59. Reisz JA, Chessler KM, Dzieciatkowska M, D'Alessandro A, Hansen KC. Blood and Plasma Proteomics: Targeted Quantitation and Posttranslational Redox Modifications. Methods Mol Biol. 2017; 1619:353-371. PMID: 28674896.
      View in: PubMed
    60. D'Alessandro A, Nemkov T, Bogren LK, Martin SL, Hansen KC. Comfortably Numb and Back: Plasma Metabolomics Reveals Biochemical Adaptations in the Hibernating 13-Lined Ground Squirrel. J Proteome Res. 2017 02 03; 16(2):958-969. PMID: 27991798.
      View in: PubMed
    61. Goddard ET, Hill RC, Nemkov T, D'Alessandro A, Hansen KC, Maller O, Mongoue-Tchokote S, Mori M, Partridge AH, Borges VF, Schedin P. The Rodent Liver Undergoes Weaning-Induced Involution and Supports Breast Cancer Metastasis. Cancer Discov. 2017 02; 7(2):177-187. PMID: 27974414.
      View in: PubMed
    62. Slaughter AL, D'Alessandro A, Moore EE, Banerjee A, Silliman CC, Hansen KC, Reisz JA, Fragoso M, Wither MJ, Bacon AW, Moore HB, Peltz ED. Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock. J Trauma Acute Care Surg. 2016 12; 81(6):1012-1019. PMID: 27602903.
      View in: PubMed
    63. Pei S, Minhajuddin M, D'Alessandro A, Nemkov T, Stevens BM, Adane B, Khan N, Hagen FK, Yadav VK, De S, Ashton JM, Hansen KC, Gutman JA, Pollyea DA, Crooks PA, Smith C, Jordan CT. Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells. J Biol Chem. 2016 11 25; 291(48):25280. PMID: 27888238.
      View in: PubMed
    64. D'Alessandro A, Nemkov T, Yoshida T, Bordbar A, Palsson BO, Hansen KC. Citrate metabolism in red blood cells stored in additive solution-3. Transfusion. 2017 02; 57(2):325-336. PMID: 27813142.
      View in: PubMed
    65. Wither MJ, Hansen KC, Reisz JA. Mass Spectrometry-Based Bottom-Up Proteomics: Sample Preparation, LC-MS/MS Analysis, and Database Query Strategies. Curr Protoc Protein Sci. 2016 Nov 01; 86:16.4.1-16.4.20. PMID: 27801520.
      View in: PubMed
    66. Goddard ET, Hill RC, Barrett A, Betts C, Guo Q, Maller O, Borges VF, Hansen KC, Schedin P. Quantitative extracellular matrix proteomics to study mammary and liver tissue microenvironments. Int J Biochem Cell Biol. 2016 12; 81(Pt A):223-232. PMID: 27771439.
      View in: PubMed
    67. Gregory MA, D'Alessandro A, Alvarez-Calderon F, Kim J, Nemkov T, Adane B, Rozhok AI, Kumar A, Kumar V, Pollyea DA, Wempe MF, Jordan CT, Serkova NJ, Tan AC, Hansen KC, DeGregori J. ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia. Proc Natl Acad Sci U S A. 2016 10 25; 113(43):E6669-E6678. PMID: 27791036.
      View in: PubMed
    68. McCurdy CE, Schenk S, Hetrick B, Houck J, Drew BG, Kaye S, Lashbrook M, Bergman BC, Takahashi DL, Dean TA, Nemkov T, Gertsman I, Hansen KC, Philp A, Hevener AL, Chicco AJ, Aagaard KM, Grove KL, Friedman JE. Maternal obesity reduces oxidative capacity in fetal skeletal muscle of Japanese macaques. JCI Insight. 2016 Oct 06; 1(16):e86612. PMID: 27734025.
      View in: PubMed
    69. Liu WH, Roemer SC, Zhou Y, Shen ZJ, Dennehey BK, Balsbaugh JL, Liddle JC, Nemkov T, Ahn NG, Hansen KC, Tyler JK, Churchill ME. The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones. Elife. 2016 Sep 30; 5. PMID: 27690308.
      View in: PubMed
    70. Calle EA, Hill RC, Leiby KL, Le AV, Gard AL, Madri JA, Hansen KC, Niklason LE. Targeted proteomics effectively quantifies differences between native lung and detergent-decellularized lung extracellular matrices. Acta Biomater. 2016 12; 46:91-100. PMID: 27693690.
      View in: PubMed
    71. D'Alessandro A, Nemkov T, Sun K, Liu H, Song A, Monte AA, Subudhi AW, Lovering AT, Dvorkin D, Julian CG, Kevil CG, Kolluru GK, Shiva S, Gladwin MT, Xia Y, Hansen KC, Roach RC. AltitudeOmics: Red Blood Cell Metabolic Adaptation to High Altitude Hypoxia. J Proteome Res. 2016 10 07; 15(10):3883-3895. PMID: 27646145.
      View in: PubMed
    72. Gamboni F, Anderson C, Mitra S, Reisz JA, Nemkov T, Dzieciatkowska M, Jones KL, Hansen KC, D'Alessandro A, Banerjee A. Hypertonic Saline Primes Activation of the p53-p21 Signaling Axis in Human Small Airway Epithelial Cells That Prevents Inflammation Induced by Pro-inflammatory Cytokines. J Proteome Res. 2016 10 07; 15(10):3813-3826. PMID: 27529569.
      View in: PubMed
    73. Pei S, Minhajuddin M, D'Alessandro A, Nemkov T, Stevens BM, Adane B, Khan N, Hagen FK, Yadav VK, De S, Ashton JM, Hansen KC, Gutman JA, Pollyea DA, Crooks PA, Smith C, Jordan CT. Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells. J Biol Chem. 2016 Oct 14; 291(42):21984-22000. PMID: 27573247.
      View in: PubMed
    74. Li M, Riddle S, Zhang H, D'Alessandro A, Flockton A, Serkova NJ, Hansen KC, Moldvan R, McKeon BA, Frid M, Kumar S, Li H, Liu H, Caánovas A, Medrano JF, Thomas MG, Iloska D, Plecitá-Hlavatá L, Ježek P, Pullamsetti S, Fini MA, El Kasmi KC, Zhang Q, Stenmark KR. Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1. Circulation. 2016 Oct 11; 134(15):1105-1121. PMID: 27562971.
      View in: PubMed
    75. Paglia G, D'Alessandro A, Rolfsson Ó, Sigurjónsson ÓE, Bordbar A, Palsson S, Nemkov T, Hansen KC, Gudmundsson S, Palsson BO. Biomarkers defining the metabolic age of red blood cells during cold storage. Blood. 2016 09 29; 128(13):e43-50. PMID: 27554084.
      View in: PubMed
    76. Liu H, Zhang Y, Wu H, D'Alessandro A, Yegutkin GG, Song A, Sun K, Li J, Cheng NY, Huang A, Edward Wen Y, Weng TT, Luo F, Nemkov T, Sun H, Kellems RE, Karmouty-Quintana H, Hansen KC, Zhao B, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Eltzschig HK, Blackburn MR, Roach RC, Xia Y. Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia. Circulation. 2016 Aug 02; 134(5):405-21. PMID: 27482003.
      View in: PubMed
    77. D'Alessandro A, Moore HB, Moore EE, Wither MJ, Nemkov T, Morton AP, Gonzalez E, Chapman MP, Fragoso M, Slaughter A, Sauaia A, Silliman CC, Hansen KC, Banerjee A. Plasma First Resuscitation Reduces Lactate Acidosis, Enhances Redox Homeostasis, Amino Acid and Purine Catabolism in a Rat Model of Profound Hemorrhagic Shock. Shock. 2016 08; 46(2):173-82. PMID: 26863033.
      View in: PubMed
    78. Sun K, Zhang Y, D'Alessandro A, Nemkov T, Song A, Wu H, Liu H, Adebiyi M, Huang A, Wen YE, Bogdanov MV, Vila A, O'Brien J, Kellems RE, Dowhan W, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Safo M, Hansen KC, Roach RC, Xia Y. Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia. Nat Commun. 2016 07 15; 7:12086. PMID: 27417539.
      View in: PubMed
    79. Reisz JA, Wither MJ, Dzieciatkowska M, Nemkov T, Issaian A, Yoshida T, Dunham AJ, Hill RC, Hansen KC, D'Alessandro A. Oxidative modifications of glyceraldehyde 3-phosphate dehydrogenase regulate metabolic reprogramming of stored red blood cells. Blood. 2016 09 22; 128(12):e32-42. PMID: 27405778.
      View in: PubMed
    80. Tzounakas VL, Kriebardis AG, Georgatzakou HT, Foudoulaki-Paparizos LE, Dzieciatkowska M, Wither MJ, Nemkov T, Hansen KC, Papassideri IS, D'Alessandro A, Antonelou MH. Data on how several physiological parameters of stored red blood cells are similar in glucose 6-phosphate dehydrogenase deficient and sufficient donors. Data Brief. 2016 Sep; 8:618-27. PMID: 27437434.
      View in: PubMed
    81. Champagne DP, Hatle KM, Fortner KA, D'Alessandro A, Thornton TM, Yang R, Torralba D, Tomás-Cortázar J, Jun YW, Ahn KH, Hansen KC, Haynes L, Anguita J, Rincon M. Fine-Tuning of CD8(+) T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus. Immunity. 2016 06 21; 44(6):1299-311. PMID: 27234056.
      View in: PubMed
    82. D'alessandro A, Nemkov T, Moore HB, Moore EE, Wither M, Nydam T, Slaughter A, Silliman CC, Banerjee A, Hansen KC. Metabolomics of trauma-associated death: shared and fluid-specific features of human plasma vs lymph. Blood Transfus. 2016 05; 14(2):185-94. PMID: 27177401.
      View in: PubMed
    83. Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2016 05; 22(5):497-505. PMID: 27089513.
      View in: PubMed
    84. Tzounakas VL, Kriebardis AG, Georgatzakou HT, Foudoulaki-Paparizos LE, Dzieciatkowska M, Wither MJ, Nemkov T, Hansen KC, Papassideri IS, D'Alessandro A, Antonelou MH. Glucose 6-phosphate dehydrogenase deficient subjects may be better "storers" than donors of red blood cells. Free Radic Biol Med. 2016 07; 96:152-65. PMID: 27094493.
      View in: PubMed
    85. Newsom SA, Brozinick JT, Kiseljak-Vassiliades K, Strauss AN, Bacon SD, Kerege AA, Bui HH, Sanders P, Siddall P, Wei T, Thomas M, Kuo MS, Nemkov T, D'Alessandro A, Hansen KC, Perreault L, Bergman BC. Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans. J Appl Physiol (1985). 2016 Jun 01; 120(11):1355-63. PMID: 27032901.
      View in: PubMed
    86. Goodman SR, Pace BS, Hansen KC, D'alessandro A, Xia Y, Daescu O, Glatt SJ. Minireview: Multiomic candidate biomarkers for clinical manifestations of sickle cell severity: Early steps to precision medicine. Exp Biol Med (Maywood). 2016 Apr; 241(7):772-81. PMID: 27022133.
      View in: PubMed
    87. Han KJ, Foster D, Harhaj EW, Dzieciatkowska M, Hansen K, Liu CW. Monoubiquitination of survival motor neuron regulates its cellular localization and Cajal body integrity. Hum Mol Genet. 2016 Apr 01; 25(7):1392-405. PMID: 26908624.
      View in: PubMed
    88. D'Alessandro A, Dzieciatkowska M, Hill RC, Hansen KC. Supernatant protein biomarkers of red blood cell storage hemolysis as determined through an absolute quantification proteomics technology. Transfusion. 2016 06; 56(6):1329-39. PMID: 26813021.
      View in: PubMed
    89. Ungerleider JL, Johnson TD, Hernandez MJ, Elhag DI, Braden RL, Dzieciatkowska M, Osborn KG, Hansen KC, Mahmud E, Christman KL. Extracellular Matrix Hydrogel Promotes Tissue Remodeling, Arteriogenesis, and Perfusion in a Rat Hindlimb Ischemia Model. JACC Basic Transl Sci. 2016 Jan-Feb; 1(1-2):32-44. PMID: 27104218.
      View in: PubMed
    90. Nemkov T, Hansen KC, Dumont LJ, D'Alessandro A. Metabolomics in transfusion medicine. Transfusion. 2016 Apr; 56(4):980-93. PMID: 26662506.
      View in: PubMed
    91. Moore HB, Moore EE, Morton AP, Gonzalez E, Fragoso M, Chapman MP, Dzieciatkowska M, Hansen KC, Banerjee A, Sauaia A, Silliman CC. Shock-induced systemic hyperfibrinolysis is attenuated by plasma-first resuscitation. J Trauma Acute Care Surg. 2015 Dec; 79(6):897-903; discussion 903-4. PMID: 26680132.
      View in: PubMed
    92. D'alessandro A, Nemkov T, Hansen KC. Rapid detection of DEHP in packed red blood cells stored under European and US standard conditions. Blood Transfus. 2016 Mar; 14(2):140-4. PMID: 26674826.
      View in: PubMed
    93. Wither M, Dzieciatkowska M, Nemkov T, Strop P, D'Alessandro A, Hansen KC. Hemoglobin oxidation at functional amino acid residues during routine storage of red blood cells. Transfusion. 2016 Feb; 56(2):421-6. PMID: 26426339.
      View in: PubMed
    94. Johnson TD, Hill RC, Dzieciatkowska M, Nigam V, Behfar A, Christman KL, Hansen KC. Quantification of decellularized human myocardial matrix: A comparison of six patients. Proteomics Clin Appl. 2016 Jan; 10(1):75-83. PMID: 26172914.
      View in: PubMed
    95. Moore HB, Moore EE, Chapman MP, Gonzalez E, Slaughter AL, Morton AP, D'Alessandro A, Hansen KC, Sauaia A, Banerjee A, Silliman CC. Viscoelastic measurements of platelet function, not fibrinogen function, predicts sensitivity to tissue-type plasminogen activator in trauma patients. J Thromb Haemost. 2015 Oct; 13(10):1878-87. PMID: 26256459.
      View in: PubMed
    96. D'Amato NC, Rogers TJ, Gordon MA, Greene LI, Cochrane DR, Spoelstra NS, Nemkov TG, D'Alessandro A, Hansen KC, Richer JK. A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer. Cancer Res. 2015 Nov 01; 75(21):4651-64. PMID: 26363006.
      View in: PubMed
    97. Woodman J, Hoffman M, Dzieciatkowska M, Hansen KC, Megee PC. Phosphorylation of the Scc2 cohesin deposition complex subunit regulates chromosome condensation through cohesin integrity. Mol Biol Cell. 2015 Nov 01; 26(21):3754-67. PMID: 26354421.
      View in: PubMed
    98. D'Alessandro A, Nemkov T, Hansen KC, Szczepiorkowski ZM, Dumont LJ. Red blood cell storage in additive solution-7 preserves energy and redox metabolism: a metabolomics approach. Transfusion. 2015 Dec; 55(12):2955-66. PMID: 26271632.
      View in: PubMed
    99. D'Alessandro A, Slaughter AL, Peltz ED, Moore EE, Silliman CC, Wither M, Nemkov T, Bacon AW, Fragoso M, Banerjee A, Hansen KC. Trauma/hemorrhagic shock instigates aberrant metabolic flux through glycolytic pathways, as revealed by preliminary (13)C-glucose labeling metabolomics. J Transl Med. 2015 Aug 05; 13:253. PMID: 26242576.
      View in: PubMed
    100. Bock A, Tucker N, Kelher MR, Khan SY, Gonzalez E, Wohlauer M, Hansen K, Dzieciatkowska M, Sauaia A, Banerjee A, Moore EE, Silliman CC. a-Enolase Causes Proinflammatory Activation of Pulmonary Microvascular Endothelial Cells and Primes Neutrophils Through Plasmin Activation of Protease-Activated Receptor 2. Shock. 2015 Aug; 44(2):137-42. PMID: 25944790.
      View in: PubMed
    101. Mosher J, Zhang W, Blumhagen RZ, D'Alessandro A, Nemkov T, Hansen KC, Hesselberth JR, Reis T. Coordination between Drosophila Arc1 and a specific population of brain neurons regulates organismal fat. Dev Biol. 2015 Sep 15; 405(2):280-90. PMID: 26209258.
      View in: PubMed
    102. Nemkov T, D'Alessandro A, Hansen KC. Three-minute method for amino acid analysis by UHPLC and high-resolution quadrupole orbitrap mass spectrometry. Amino Acids. 2015 Nov; 47(11):2345-57. PMID: 26058356.
      View in: PubMed
    103. Merna N, Fung KM, Wang JJ, King CR, Hansen KC, Christman KL, George SC. Differential ß3 Integrin Expression Regulates the Response of Human Lung and Cardiac Fibroblasts to Extracellular Matrix and Its Components. Tissue Eng Part A. 2015 Aug; 21(15-16):2195-205. PMID: 25926101.
      View in: PubMed
    104. Moore EE, Moore HB, Gonzalez E, Chapman MP, Hansen KC, Sauaia A, Silliman CC, Banerjee A. Postinjury fibrinolysis shutdown: Rationale for selective tranexamic acid. J Trauma Acute Care Surg. 2015 Jun; 78(6 Suppl 1):S65-9. PMID: 26002266.
      View in: PubMed
    105. Hill RC, Wither MJ, Nemkov T, Barrett A, D'Alessandro A, Dzieciatkowska M, Hansen KC. Preserved Proteins from Extinct Bison latifrons Identified by Tandem Mass Spectrometry; Hydroxylysine Glycosides are a Common Feature of Ancient Collagen. Mol Cell Proteomics. 2015 Jul; 14(7):1946-58. PMID: 25948757.
      View in: PubMed
    106. Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF. Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development. 2015 May 01; 142(9):1616-27. PMID: 25922525.
      View in: PubMed
    107. D'Alessandro A, Moore HB, Moore EE, Wither M, Nemkov T, Gonzalez E, Slaughter A, Fragoso M, Hansen KC, Silliman CC, Banerjee A. Early hemorrhage triggers metabolic responses that build up during prolonged shock. Am J Physiol Regul Integr Comp Physiol. 2015 Jun 15; 308(12):R1034-44. PMID: 25876652.
      View in: PubMed
    108. Peltz ED, D'Alessandro A, Moore EE, Chin T, Silliman CC, Sauaia A, Hansen KC, Banerjee A. Pathologic metabolism: an exploratory study of the plasma metabolome of critical injury. J Trauma Acute Care Surg. 2015 Apr; 78(4):742-51. PMID: 25807403.
      View in: PubMed
    109. Moore HB, Moore EE, Gonzalez E, Wiener G, Chapman MP, Dzieciatkowska M, Sauaia A, Banerjee A, Hansen KC, Silliman C. Plasma is the physiologic buffer of tissue plasminogen activator-mediated fibrinolysis: rationale for plasma-first resuscitation after life-threatening hemorrhage. J Am Coll Surg. 2015 May; 220(5):872-9. PMID: 25840538.
      View in: PubMed
    110. Hansen KC, D'Alessandro A, Clement CC, Santambrogio L. Lymph formation, composition and circulation: a proteomics perspective. Int Immunol. 2015 May; 27(5):219-27. PMID: 25788586.
      View in: PubMed
    111. Dzieciatkowska M, D'Alessandro A, Hill RC, Hansen KC. Plasma QconCATs reveal a gender-specific proteomic signature in apheresis platelet plasma supernatants. J Proteomics. 2015 Apr 29; 120:1-6. PMID: 25743772.
      View in: PubMed
    112. Zhang L, Li X, Hill RC, Qiu Y, Zhang W, Hansen KC, Zhao R. Brr2 plays a role in spliceosomal activation in addition to U4/U6 unwinding. Nucleic Acids Res. 2015 Mar 31; 43(6):3286-97. PMID: 25670679.
      View in: PubMed
    113. Hill RC, Calle EA, Dzieciatkowska M, Niklason LE, Hansen KC. Quantification of extracellular matrix proteins from a rat lung scaffold to provide a molecular readout for tissue engineering. Mol Cell Proteomics. 2015 Apr; 14(4):961-73. PMID: 25660013.
      View in: PubMed
    114. Moore HB, Moore EE, Gonzalez E, Hansen KC, Dzieciatkowska M, Chapman MP, Sauaia A, West B, Banerjee A, Silliman CC. Hemolysis exacerbates hyperfibrinolysis, whereas platelolysis shuts down fibrinolysis: evolving concepts of the spectrum of fibrinolysis in response to severe injury. Shock. 2015 Jan; 43(1):39-46. PMID: 25072794.
      View in: PubMed
    115. D'Alessandro A, Nemkov T, Kelher M, West FB, Schwindt RK, Banerjee A, Moore EE, Silliman CC, Hansen KC. Routine storage of red blood cell (RBC) units in additive solution-3: a comprehensive investigation of the RBC metabolome. Transfusion. 2015 Jun; 55(6):1155-68. PMID: 25556331.
      View in: PubMed
    116. D'Alessandro A, Dzieciatkowska M, Peltz ED, Moore EE, Jordan JR, Silliman CC, Banerjee A, Hansen KC. Dynamic changes in rat mesenteric lymph proteins following trauma using label-free mass spectrometry. Shock. 2014 Dec; 42(6):509-17. PMID: 25243424.
      View in: PubMed
    117. Dzieciatkowska M, D'Alessandro A, Moore EE, Wohlauer M, Banerjee A, Silliman CC, Hansen KC. Lymph is not a plasma ultrafiltrate: a proteomic analysis of injured patients. Shock. 2014 Dec; 42(6):485-498. PMID: 25243428.
      View in: PubMed
    118. D'Alessandro A, Hansen KC, Silliman CC, Moore EE, Kelher M, Banerjee A. Metabolomics of AS-5 RBC supernatants following routine storage. Vox Sang. 2015 Feb; 108(2):131-40. PMID: 25200932.
      View in: PubMed
    119. Dzieciatkowska M, D'Alessandro A, Burke TA, Kelher MR, Moore EE, Banerjee A, Silliman CC, West BF, Hansen KC. Proteomics of apheresis platelet supernatants during routine storage: Gender-related differences. J Proteomics. 2015 Jan 01; 112:190-209. PMID: 25201077.
      View in: PubMed
    120. D'Alessandro A, Kriebardis AG, Rinalducci S, Antonelou MH, Hansen KC, Papassideri IS, Zolla L. An update on red blood cell storage lesions, as gleaned through biochemistry and omics technologies. Transfusion. 2015 Jan; 55(1):205-19. PMID: 25130459.
      View in: PubMed
    121. Gamboni F, Escobar GA, Moore EE, Dzieciatkowska M, Hansen KC, Mitra S, Nydam TA, Silliman CC, Banerjee A. Clathrin complexes with the inhibitor kappa B kinase signalosome: imaging the interactome. Physiol Rep. 2014 Jul 01; 2(7). PMID: 24994893.
      View in: PubMed
    122. McReynolds S, Dzieciatkowska M, Stevens J, Hansen KC, Schoolcraft WB, Katz-Jaffe MG. Toward the identification of a subset of unexplained infertility: a sperm proteomic approach. Fertil Steril. 2014 Sep; 102(3):692-9. PMID: 24934493.
      View in: PubMed
    123. Chen JF, Zhang Y, Wilde J, Hansen KC, Lai F, Niswander L. Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size. Nat Commun. 2014 May 30; 5:3885. PMID: 24875059.
      View in: PubMed
    124. Moore EE, Chin TL, Chapman MC, Gonzalez E, Moore HB, Silliman CC, Hansen KC, Sauaia A, Banerjee A. Plasma first in the field for postinjury hemorrhagic shock. Shock. 2014 May; 41 Suppl 1:35-8. PMID: 24317352.
      View in: PubMed
    125. Woodman J, Fara T, Dzieciatkowska M, Trejo M, Luong N, Hansen KC, Megee PC. Cell cycle-specific cleavage of Scc2 regulates its cohesin deposition activity. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):7060-5. PMID: 24778232.
      View in: PubMed
    126. Dzieciatkowska M, Hill R, Hansen KC. GeLC-MS/MS analysis of complex protein mixtures. Methods Mol Biol. 2014; 1156:53-66. PMID: 24791981.
      View in: PubMed
    127. Julian CG, Subudhi AW, Hill RC, Wilson MJ, Dimmen AC, Hansen KC, Roach RC. Exploratory proteomic analysis of hypobaric hypoxia and acute mountain sickness in humans. J Appl Physiol (1985). 2014 Apr 01; 116(7):937-44. PMID: 24265281.
      View in: PubMed
    128. Li J, Hansen KC, Zhang Y, Dong C, Dinu CZ, Dzieciatkowska M, Pei M. Rejuvenation of chondrogenic potential in a young stem cell microenvironment. Biomaterials. 2014 Jan; 35(2):642-53. PMID: 24148243.
      View in: PubMed
    129. Maller O, Hansen KC, Lyons TR, Acerbi I, Weaver VM, Prekeris R, Tan AC, Schedin P. Collagen architecture in pregnancy-induced protection from breast cancer. J Cell Sci. 2013 Sep 15; 126(Pt 18):4108-10. PMID: 23843613.
      View in: PubMed
    130. Dzieciatkowska M, Silliman CC, Moore EE, Kelher MR, Banerjee A, Land KJ, Ellison M, West FB, Ambruso DR, Hansen KC. Proteomic analysis of the supernatant of red blood cell units: the effects of storage and leucoreduction. Vox Sang. 2013 Oct; 105(3):210-8. PMID: 23663258.
      View in: PubMed
    131. Li X, Zhang W, Xu T, Ramsey J, Zhang L, Hill R, Hansen KC, Hesselberth JR, Zhao R. Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly. Nucleic Acids Res. 2013 Apr 01; 41(6):3805-18. PMID: 23393194.
      View in: PubMed
    132. Lee L, Moore EE, Hansen KC, Silliman CC, Chandler JG, Banerjee A. It's not your grandfather's field plasma. Surgery. 2013 Jun; 153(6):857-60. PMID: 23122899.
      View in: PubMed
    133. Han KJ, Foster DG, Zhang NY, Kanisha K, Dzieciatkowska M, Sclafani RA, Hansen KC, Peng J, Liu CW. Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron. J Biol Chem. 2012 Dec 21; 287(52):43741-52. PMID: 23112048.
      View in: PubMed
    134. McReynolds S, Dzieciatkowska M, McCallie BR, Mitchell SD, Stevens J, Hansen K, Schoolcraft WB, Katz-Jaffe MG. Impact of maternal aging on the molecular signature of human cumulus cells. Fertil Steril. 2012 Dec; 98(6):1574-80.e5. PMID: 22968048.
      View in: PubMed
    135. O'Brien JH, Vanderlinden LA, Schedin PJ, Hansen KC. Rat mammary extracellular matrix composition and response to ibuprofen treatment during postpartum involution by differential GeLC-MS/MS analysis. J Proteome Res. 2012 Oct 05; 11(10):4894-905. PMID: 22897585.
      View in: PubMed
    136. Brannan K, Kim H, Erickson B, Glover-Cutter K, Kim S, Fong N, Kiemele L, Hansen K, Davis R, Lykke-Andersen J, Bentley DL. mRNA decapping factors and the exonuclease Xrn2 function in widespread premature termination of RNA polymerase II transcription. Mol Cell. 2012 May 11; 46(3):311-24. PMID: 22483619.
      View in: PubMed
    137. Estrada-Bernal A, Sanford SD, Sosa LJ, Simon GC, Hansen KC, Pfenninger KH. Functional complexity of the axonal growth cone: a proteomic analysis. PLoS One. 2012; 7(2):e31858. PMID: 22384089.
      View in: PubMed
    138. Vrljic M, Strop P, Hill RC, Hansen KC, Chu S, Brunger AT. Post-translational modifications and lipid binding profile of insect cell-expressed full-length mammalian synaptotagmin 1. Biochemistry. 2011 Nov 22; 50(46):9998-10012. PMID: 21928778.
      View in: PubMed
    139. Silliman CC, Dzieciatkowska M, Moore EE, Kelher MR, Banerjee A, Liang X, Land KJ, Hansen KC. Proteomic analyses of human plasma: Venus versus Mars. Transfusion. 2012 Feb; 52(2):417-24. PMID: 21880043.
      View in: PubMed
    140. Dzieciatkowska M, Wohlauer MV, Moore EE, Damle S, Peltz E, Campsen J, Kelher M, Silliman C, Banerjee A, Hansen KC. Proteomic analysis of human mesenteric lymph. Shock. 2011 Apr; 35(4):331-8. PMID: 21192285.
      View in: PubMed
    141. McReynolds S, Vanderlinden L, Stevens J, Hansen K, Schoolcraft WB, Katz-Jaffe MG. Lipocalin-1: a potential marker for noninvasive aneuploidy screening. Fertil Steril. 2011 Jun 30; 95(8):2631-3. PMID: 21324447.
      View in: PubMed
    142. O'Brien J, Hansen K, Barkan D, Green J, Schedin P, O'Brien J, Hansen K, Barkan D, Green J, Schedin P. Non-steroidal anti-inflammatory drugs target the pro-tumorigenic extracellular matrix of the postpartum mammary gland. Int J Dev Biol. 2011; 55(7-9):745-55. PMID: 22161831.
      View in: PubMed
    143. Zurawel A, Moore EE, Peltz ED, Jordan JR, Damle S, Dzieciatkowska M, Banerjee A, Hansen KC. Proteomic profiling of the mesenteric lymph after hemorrhagic shock: Differential gel electrophoresis and mass spectrometry analysis. Clin Proteomics. 2010 Nov 10; 8(1):1. PMID: 21906351.
      View in: PubMed
    144. Nelson AC, Lyons TR, Young CD, Hansen KC, Anderson SM, Holt JT. AKT regulates BRCA1 stability in response to hormone signaling. Mol Cell Endocrinol. 2010 May 05; 319(1-2):129-42. PMID: 20085797.
      View in: PubMed
    145. Curtis BR, Cox NJ, Sullivan MJ, Konkashbaev A, Bowens K, Hansen K, Aster RH. The neutrophil alloantigen HNA-3a (5b) is located on choline transporter-like protein 2 and appears to be encoded by an R>Q154 amino acid substitution. Blood. 2010 Mar 11; 115(10):2073-6. PMID: 20040764.
      View in: PubMed
    146. Zhao M, Zhang NY, Zurawel A, Hansen KC, Liu CW. Degradation of some polyubiquitinated proteins requires an intrinsic proteasomal binding element in the substrates. J Biol Chem. 2010 Feb 12; 285(7):4771-80. PMID: 20007692.
      View in: PubMed
    147. Peltz ED, Moore EE, Zurawel AA, Jordan JR, Damle SS, Redzic JS, Masuno T, Eun J, Hansen KC, Banerjee A. Proteome and system ontology of hemorrhagic shock: exploring early constitutive changes in postshock mesenteric lymph. Surgery. 2009 Aug; 146(2):347-57. PMID: 19628095.
      View in: PubMed
    148. Porterfield HS, Murray KS, Schlichting DG, Chen X, Hansen KC, Duncan MW, Dreskin SC. Effector activity of peanut allergens: a critical role for Ara h 2, Ara h 6, and their variants. Clin Exp Allergy. 2009 Jul; 39(7):1099-108. PMID: 19438581.
      View in: PubMed
    149. Hansen KC, Kiemele L, Maller O, O'Brien J, Shankar A, Fornetti J, Schedin P. An in-solution ultrasonication-assisted digestion method for improved extracellular matrix proteome coverage. Mol Cell Proteomics. 2009 Jul; 8(7):1648-57. PMID: 19351662.
      View in: PubMed
    150. Das C, Lucia MS, Hansen KC, Tyler JK. CBP/p300-mediated acetylation of histone H3 on lysine 56. Nature. 2009 May 07; 459(7243):113-7. PMID: 19270680.
      View in: PubMed
    151. Hattar R, Maller O, McDaniel S, Hansen KC, Hedman KJ, Lyons TR, Lucia S, Wilson RS, Schedin P. Tamoxifen induces pleiotrophic changes in mammary stroma resulting in extracellular matrix that suppresses transformed phenotypes. Breast Cancer Res. 2009; 11(1):R5. PMID: 19173736.
      View in: PubMed
    152. Kipnis E, Hansen K, Sawa T, Moriyama K, Zurawel A, Ishizaka A, Wiener-Kronish J. Proteomic analysis of undiluted lung epithelial lining fluid. Chest. 2008 Aug; 134(2):338-345. PMID: 18682457.
      View in: PubMed
    153. Hirsch J, Niemann CU, Hansen KC, Choi S, Su X, Frank JA, Fang X, Hirose R, Theodore P, Sapru A, Burlingame AL, Matthay MA. Alterations in the proteome of pulmonary alveolar type II cells in the rat after hepatic ischemia-reperfusion. Crit Care Med. 2008 Jun; 36(6):1846-54. PMID: 18496381.
      View in: PubMed
    154. Howell MD, Fairchild HR, Kim BE, Bin L, Boguniewicz M, Redzic JS, Hansen KC, Leung DY. Th2 cytokines act on S100/A11 to downregulate keratinocyte differentiation. J Invest Dermatol. 2008 Sep; 128(9):2248-58. PMID: 18385759.
      View in: PubMed
    155. Jordan JR, Moore EE, Damle SS, Eckels P, Johnson JL, Roach JP, Redzic JS, Hansen KC, Banerjee A. Gelsolin is depleted in post-shock mesenteric lymph. J Surg Res. 2007 Nov; 143(1):130-5. PMID: 17950082.
      View in: PubMed
    156. Chen Z, Zang J, Kappler J, Hong X, Crawford F, Wang Q, Lan F, Jiang C, Whetstine J, Dai S, Hansen K, Shi Y, Zhang G. Structural basis of the recognition of a methylated histone tail by JMJD2A. Proc Natl Acad Sci U S A. 2007 Jun 26; 104(26):10818-23. PMID: 17567753.
      View in: PubMed
    157. McDermott RA, Porterfield HS, El Mezayen R, Burks AW, Pons L, Schlichting DG, Solomon B, Redzic JS, Harbeck RJ, Duncan MW, Hansen KC, Dreskin SC. Contribution of Ara h 2 to peanut-specific, immunoglobulin E-mediated, cell activation. Clin Exp Allergy. 2007 May; 37(5):752-63. PMID: 17456223.
      View in: PubMed
    158. Hirsch J, Hansen KC, Sapru A, Frank JA, Chalkley RJ, Fang X, Trinidad JC, Baker P, Burlingame AL, Matthay MA. Impact of low and high tidal volumes on the rat alveolar epithelial type II cell proteome. Am J Respir Crit Care Med. 2007 May 15; 175(10):1006-13. PMID: 17363773.
      View in: PubMed
    159. Chen Z, Zang J, Whetstine J, Hong X, Davrazou F, Kutateladze TG, Simpson M, Mao Q, Pan CH, Dai S, Hagman J, Hansen K, Shi Y, Zhang G. Structural insights into histone demethylation by JMJD2 family members. Cell. 2006 May 19; 125(4):691-702. PMID: 16677698.
      View in: PubMed
    160. Hirsch J, Hansen KC, Choi S, Noh J, Hirose R, Roberts JP, Matthay MA, Burlingame AL, Maher JJ, Niemann CU. Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats. Mol Cell Proteomics. 2006 Jun; 5(6):979-86. PMID: 16500929.
      View in: PubMed
    161. Chalkley RJ, Baker PR, Huang L, Hansen KC, Allen NP, Rexach M, Burlingame AL. Comprehensive analysis of a multidimensional liquid chromatography mass spectrometry dataset acquired on a quadrupole selecting, quadrupole collision cell, time-of-flight mass spectrometer: II. New developments in Protein Prospector allow for reliable and comprehensive automatic analysis of large datasets. Mol Cell Proteomics. 2005 Aug; 4(8):1194-204. PMID: 15937296.
      View in: PubMed
    162. Chalkley RJ, Baker PR, Hansen KC, Medzihradszky KF, Allen NP, Rexach M, Burlingame AL. Comprehensive analysis of a multidimensional liquid chromatography mass spectrometry dataset acquired on a quadrupole selecting, quadrupole collision cell, time-of-flight mass spectrometer: I. How much of the data is theoretically interpretable by search engines? Mol Cell Proteomics. 2005 Aug; 4(8):1189-93. PMID: 15923566.
      View in: PubMed
    163. Crary FJ, Clarke JT, Dougherty MK, Hanlon PG, Hansen KC, Steinberg JT, Barraclough BL, Coates AJ, Gérard JC, Grodent D, Kurth WS, Mitchell DG, Rymer AM, Young DT. Solar wind dynamic pressure and electric field as the main factors controlling Saturn's aurorae. Nature. 2005 Feb 17; 433(7027):720-2. PMID: 15716946.
      View in: PubMed
    164. Vosseller K, Hansen KC, Chalkley RJ, Trinidad JC, Wells L, Hart GW, Burlingame AL. Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol. Proteomics. 2005 Feb; 5(2):388-98. PMID: 15648052.
      View in: PubMed
    165. Chalkley RJ, Hansen KC, Baldwin MA. Bioinformatic methods to exploit mass spectrometric data for proteomic applications. Methods Enzymol. 2005; 402:289-312. PMID: 16401513.
      View in: PubMed
    166. Strop P, Bankovich AJ, Hansen KC, Garcia KC, Brunger AT. Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family. J Mol Biol. 2004 Oct 29; 343(4):1055-65. PMID: 15476821.
      View in: PubMed
    167. Becker CF, Strop P, Bass RB, Hansen KC, Locher KP, Ren G, Yeager M, Rees DC, Kochendoerfer GG. Conversion of a mechanosensitive channel protein from a membrane-embedded to a water-soluble form by covalent modification with amphiphiles. J Mol Biol. 2004 Oct 22; 343(3):747-58. PMID: 15465059.
      View in: PubMed
    168. Hirsch J, Hansen KC, Burlingame AL, Matthay MA. Proteomics: current techniques and potential applications to lung disease. Am J Physiol Lung Cell Mol Physiol. 2004 Jul; 287(1):L1-23. PMID: 15187006.
      View in: PubMed
    169. Cutillas PR, Chalkley RJ, Hansen KC, Cramer R, Norden AG, Waterfield MD, Burlingame AL, Unwin RJ. The urinary proteome in Fanconi syndrome implies specificity in the reabsorption of proteins by renal proximal tubule cells. Am J Physiol Renal Physiol. 2004 Sep; 287(3):F353-64. PMID: 15140760.
      View in: PubMed
    170. Hansen KC, Schmitt-Ulms G, Chalkley RJ, Hirsch J, Baldwin MA, Burlingame AL. Mass spectrometric analysis of protein mixtures at low levels using cleavable 13C-isotope-coded affinity tag and multidimensional chromatography. Mol Cell Proteomics. 2003 May; 2(5):299-314. PMID: 12766231.
      View in: PubMed
    Hansen's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description

    Copyright © 2019 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)