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Virginia Sarapura

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-3931

    Collapse Research 
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    F32DK008444     (SARAPURA, VIRGINIA D)May 1, 1990
    NIH/NIDDK
    @-SUBUNIT GENE EXPRESSION AND REGULATION IN THYROTROPES
    Role: Principal Investigator
    K08DK002169     (SARAPURA, VIRGINIA D)Jan 1, 1993 - Dec 31, 1998
    NIH/NIDDK
    THYROTROPIN-ALPHA SUBUNIT GENE TRANSCRIPTION FACTORS
    Role: Principal Investigator
    R03DK058952     (SARAPURA, VIRGINIA D)Sep 30, 2000 - Aug 31, 2003
    NIH/NIDDK
    ECTOPIC GLYCOPROTEIN HORMONE ALPHA-SUBUNIT
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Smith MJ, Ford BR, Rihanek M, Coleman BM, Getahun A, Sarapura VD, Gottlieb PA, Cambier JC. Elevated PTEN expression maintains anergy in human B cells and reveals unexpectedly high repertoire autoreactivity. JCI Insight. 2019 Feb 07; 4(3). PMID: 30728334.
      View in: PubMed
    2. Smith MJ, Rihanek M, Coleman BM, Gottlieb PA, Sarapura VD, Cambier JC. Activation of thyroid antigen-reactive B cells in recent onset autoimmune thyroid disease patients. J Autoimmun. 2018 05; 89:82-89. PMID: 29233566.
      View in: PubMed
    3. Tomer Y, Sarapura V, Kahaly GJ. Thyroid disorders: it's very personal. Thyroid. 2010 Jul; 20(7):677-9. PMID: 20578890.
      View in: PubMed
    4. Sarapura VD, Wood WM, Woodmansee WW, Haakinson DJ, Dowding JM, Gordon DF, Ridgway EC. Pituitary tumors arising from glycoprotein hormone alpha-subunit-deficient mice contain transcription factors and receptors present in thyrotropes. Pituitary. 2006; 9(1):11-8. PMID: 16703404.
      View in: PubMed
    5. Kerr JM, Gordon DF, Woodmansee WW, Sarapura VD, Ridgway EC, Wood WM. Growth arrest of thyrotropic tumors by thyroid hormone is correlated with novel changes in Wnt-10A. Mol Cell Endocrinol. 2005 Jun 30; 238(1-2):57-67. PMID: 15896901.
      View in: PubMed
    6. Wood WM, Sarapura VD, Dowding JM, Woodmansee WW, Haakinson DJ, Gordon DF, Ridgway EC. Early gene expression changes preceding thyroid hormone-induced involution of a thyrotrope tumor. Endocrinology. 2002 Feb; 143(2):347-59. PMID: 11796486.
      View in: PubMed
    7. Brinkmeier ML, Stahl JH, Gordon DF, Ross BD, Sarapura VD, Dowding JM, Kendall SK, Lloyd RV, Ridgway EC, Camper SA. Thyroid hormone-responsive pituitary hyperplasia independent of somatostatin receptor 2. Mol Endocrinol. 2001 Dec; 15(12):2129-36. PMID: 11731614.
      View in: PubMed
    8. Sarapura VD, Strouth HL, Wood WM, Gordon DF, Ridgway EC. Activation of the glycoprotein hormone alpha-subunit gene promoter in thyrotropes. Mol Cell Endocrinol. 1998 Nov 25; 146(1-2):77-86. PMID: 10022765.
      View in: PubMed
    9. Wood WM, Dowding JM, Sarapura VD, McDermott MT, Gordon DF, Ridgway EC. Functional interactions of an upstream enhancer of the mouse glycoprotein hormone alpha-subunit gene with proximal promoter sequences. Mol Cell Endocrinol. 1998 Jul 25; 142(1-2):141-52. PMID: 9783910.
      View in: PubMed
    10. Brinkmeier ML, Gordon DF, Dowding JM, Saunders TL, Kendall SK, Sarapura VD, Wood WM, Ridgway EC, Camper SA. Cell-specific expression of the mouse glycoprotein hormone alpha-subunit gene requires multiple interacting DNA elements in transgenic mice and cultured cells. Mol Endocrinol. 1998 May; 12(5):622-33. PMID: 9605925.
      View in: PubMed
    11. Sarapura VD, Strouth HL, Gordon DF, Wood WM, Ridgway EC. Msx1 is present in thyrotropic cells and binds to a consensus site on the glycoprotein hormone alpha-subunit promoter. Mol Endocrinol. 1997 Nov; 11(12):1782-94. PMID: 9369446.
      View in: PubMed
    12. Sarapura VD, Wood WM, Bright TM, Ocran KW, Gordon DF, Ridgway EC. Reconstitution of triiodothyronine inhibition in non-triiodothyronine-responsive thyrotropic tumor cells using transfected thyroid hormone receptor isoforms. Thyroid. 1997 Jun; 7(3):453-61. PMID: 9226219.
      View in: PubMed
    13. James RA, Sarapura VD, Bruns C, Raulf F, Dowding JM, Gordon DF, Wood WM, Ridgway EC. Thyroid hormone-induced expression of specific somatostatin receptor subtypes correlates with involution of the TtT-97 murine thyrotrope tumor. Endocrinology. 1997 Feb; 138(2):719-24. PMID: 9003007.
      View in: PubMed
    14. Kendall SK, Gordon DF, Birkmeier TS, Petrey D, Sarapura VD, O'Shea KS, Wood WM, Lloyd RV, Ridgway EC, Camper SA. Enhancer-mediated high level expression of mouse pituitary glycoprotein hormone alpha-subunit transgene in thyrotropes, gonadotropes, and developing pituitary gland. Mol Endocrinol. 1994 Oct; 8(10):1420-33. PMID: 7531821.
      View in: PubMed
    15. Gordon DF, Haugen BR, Sarapura VD, Nelson AR, Wood WM, Ridgway EC. Analysis of Pit-1 in regulating mouse TSH beta promoter activity in thyrotropes. Mol Cell Endocrinol. 1993 Oct; 96(1-2):75-84. PMID: 8276142.
      View in: PubMed
    16. Sarapura V, Schlaff WD. Recent advances in the understanding of the pathophysiology and treatment of hyperprolactinemia. Curr Opin Obstet Gynecol. 1993 Jun; 5(3):360-7. PMID: 8329652.
      View in: PubMed
    17. Sarapura VD, Wood WM, Gordon DF, Ridgway EC. Effect of thyroid hormone on T3-receptor mRNA levels and growth of thyrotropic tumors. Mol Cell Endocrinol. 1993 Feb; 91(1-2):75-81. PMID: 8472856.
      View in: PubMed
    18. Sarapura VD, Wood WM, Gordon DF, Ridgway EC. A cell line that produces the glycoprotein hormone alpha-subunit contains specific nuclear factors similar to those present in thyrotropes. Thyroid. 1992; 2(1):31-8. PMID: 1381977.
      View in: PubMed
    19. Sarapura VD, Wood WM, Gordon DF, Ocran KW, Kao MY, Ridgway EC. Thyrotrope expression and thyroid hormone inhibition map to different regions of the mouse glycoprotein hormone alpha-subunit gene promoter. Endocrinology. 1990 Sep; 127(3):1352-61. PMID: 1696883.
      View in: PubMed
    20. Gordon DF, Wood WM, Ocran KW, Kao MY, Sarapura VD, Ridgway EC. TSH subunit gene promoters from a murine alpha-subunit producing tumor function normally. Mol Cell Endocrinol. 1990 Jun 18; 71(2):93-103. PMID: 2376287.
      View in: PubMed
    21. Ocran KW, Sarapura VD, Wood WM, Gordon DF, Gutierrez-Hartmann A, Ridgway EC. Identification of cis-acting promoter elements important for expression of the mouse glycoprotein hormone alpha-subunit gene in thyrotropes. Mol Endocrinol. 1990 May; 4(5):766-72. PMID: 1703276.
      View in: PubMed
    22. Ridgway EC, Gordon DF, Kao M, Sarapura V, Ocran K, Alexander L, Wood WM. Transcriptional regulation of the murine TSH subunit genes. Horm Metab Res Suppl. 1990; 23:5-9. PMID: 2210633.
      View in: PubMed
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