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Virginia Sarapura M.D.

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-3931

    Collapse Research 
    Collapse research activities and funding
    R03DK058952     (SARAPURA, VIRGINIA D)Sep 30, 2000 - Aug 31, 2003
    NIH
    ECTOPIC GLYCOPROTEIN HORMONE ALPHA-SUBUNIT
    Role: Principal Investigator
    K08DK002169     (SARAPURA, VIRGINIA D)Jan 1, 1993 - Dec 31, 1998
    NIH
    THYROTROPIN-ALPHA SUBUNIT GENE TRANSCRIPTION FACTORS
    Role: Principal Investigator
    F32DK008444     (SARAPURA, VIRGINIA D)May 1, 1990
    NIH
    @-SUBUNIT GENE EXPRESSION AND REGULATION IN THYROTROPES
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Stensland ZC, Coleman BM, Rihanek M, Baxter RM, Gottlieb PA, Hsieh EWY, Sarapura VD, Simmons KM, Cambier JC, Smith MJ. Peripheral immunophenotyping of AITD subjects reveals alterations in immune cells in pediatric vs adult-onset AITD. iScience. 2022 Jan 21; 25(1):103626. PMID: 35005561.
      View in: PubMed
    2. Smith MJ, Ford BR, Rihanek M, Coleman BM, Getahun A, Sarapura VD, Gottlieb PA, Cambier JC. Elevated PTEN expression maintains anergy in human B cells and reveals unexpectedly high repertoire autoreactivity. JCI Insight. 2019 Feb 07; 4(3). PMID: 30728334.
      View in: PubMed
    3. Smith MJ, Rihanek M, Coleman BM, Gottlieb PA, Sarapura VD, Cambier JC. Activation of thyroid antigen-reactive B cells in recent onset autoimmune thyroid disease patients. J Autoimmun. 2018 05; 89:82-89. PMID: 29233566.
      View in: PubMed
    4. Tomer Y, Sarapura V, Kahaly GJ. Thyroid disorders: it's very personal. Thyroid. 2010 Jul; 20(7):677-9. PMID: 20578890.
      View in: PubMed
    5. Sarapura VD, Wood WM, Woodmansee WW, Haakinson DJ, Dowding JM, Gordon DF, Ridgway EC. Pituitary tumors arising from glycoprotein hormone alpha-subunit-deficient mice contain transcription factors and receptors present in thyrotropes. Pituitary. 2006; 9(1):11-8. PMID: 16703404.
      View in: PubMed
    6. Kerr JM, Gordon DF, Woodmansee WW, Sarapura VD, Ridgway EC, Wood WM. Growth arrest of thyrotropic tumors by thyroid hormone is correlated with novel changes in Wnt-10A. Mol Cell Endocrinol. 2005 Jun 30; 238(1-2):57-67. PMID: 15896901.
      View in: PubMed
    7. Wood WM, Sarapura VD, Dowding JM, Woodmansee WW, Haakinson DJ, Gordon DF, Ridgway EC. Early gene expression changes preceding thyroid hormone-induced involution of a thyrotrope tumor. Endocrinology. 2002 Feb; 143(2):347-59. PMID: 11796486.
      View in: PubMed
    8. Brinkmeier ML, Stahl JH, Gordon DF, Ross BD, Sarapura VD, Dowding JM, Kendall SK, Lloyd RV, Ridgway EC, Camper SA. Thyroid hormone-responsive pituitary hyperplasia independent of somatostatin receptor 2. Mol Endocrinol. 2001 Dec; 15(12):2129-36. PMID: 11731614.
      View in: PubMed
    9. Sarapura VD, Strouth HL, Wood WM, Gordon DF, Ridgway EC. Activation of the glycoprotein hormone alpha-subunit gene promoter in thyrotropes. Mol Cell Endocrinol. 1998 Nov 25; 146(1-2):77-86. PMID: 10022765.
      View in: PubMed
    10. Wood WM, Dowding JM, Sarapura VD, McDermott MT, Gordon DF, Ridgway EC. Functional interactions of an upstream enhancer of the mouse glycoprotein hormone alpha-subunit gene with proximal promoter sequences. Mol Cell Endocrinol. 1998 Jul 25; 142(1-2):141-52. PMID: 9783910.
      View in: PubMed
    11. Brinkmeier ML, Gordon DF, Dowding JM, Saunders TL, Kendall SK, Sarapura VD, Wood WM, Ridgway EC, Camper SA. Cell-specific expression of the mouse glycoprotein hormone alpha-subunit gene requires multiple interacting DNA elements in transgenic mice and cultured cells. Mol Endocrinol. 1998 May; 12(5):622-33. PMID: 9605925.
      View in: PubMed
    12. Sarapura VD, Strouth HL, Gordon DF, Wood WM, Ridgway EC. Msx1 is present in thyrotropic cells and binds to a consensus site on the glycoprotein hormone alpha-subunit promoter. Mol Endocrinol. 1997 Nov; 11(12):1782-94. PMID: 9369446.
      View in: PubMed
    13. Sarapura VD, Wood WM, Bright TM, Ocran KW, Gordon DF, Ridgway EC. Reconstitution of triiodothyronine inhibition in non-triiodothyronine-responsive thyrotropic tumor cells using transfected thyroid hormone receptor isoforms. Thyroid. 1997 Jun; 7(3):453-61. PMID: 9226219.
      View in: PubMed
    14. James RA, Sarapura VD, Bruns C, Raulf F, Dowding JM, Gordon DF, Wood WM, Ridgway EC. Thyroid hormone-induced expression of specific somatostatin receptor subtypes correlates with involution of the TtT-97 murine thyrotrope tumor. Endocrinology. 1997 Feb; 138(2):719-24. PMID: 9003007.
      View in: PubMed
    15. Kendall SK, Gordon DF, Birkmeier TS, Petrey D, Sarapura VD, O'Shea KS, Wood WM, Lloyd RV, Ridgway EC, Camper SA. Enhancer-mediated high level expression of mouse pituitary glycoprotein hormone alpha-subunit transgene in thyrotropes, gonadotropes, and developing pituitary gland. Mol Endocrinol. 1994 Oct; 8(10):1420-33. PMID: 7531821.
      View in: PubMed
    16. Gordon DF, Haugen BR, Sarapura VD, Nelson AR, Wood WM, Ridgway EC. Analysis of Pit-1 in regulating mouse TSH beta promoter activity in thyrotropes. Mol Cell Endocrinol. 1993 Oct; 96(1-2):75-84. PMID: 8276142.
      View in: PubMed
    17. Sarapura V, Schlaff WD. Recent advances in the understanding of the pathophysiology and treatment of hyperprolactinemia. Curr Opin Obstet Gynecol. 1993 Jun; 5(3):360-7. PMID: 8329652.
      View in: PubMed
    18. Sarapura VD, Wood WM, Gordon DF, Ridgway EC. Effect of thyroid hormone on T3-receptor mRNA levels and growth of thyrotropic tumors. Mol Cell Endocrinol. 1993 Feb; 91(1-2):75-81. PMID: 8472856.
      View in: PubMed
    19. Sarapura VD, Wood WM, Gordon DF, Ridgway EC. A cell line that produces the glycoprotein hormone alpha-subunit contains specific nuclear factors similar to those present in thyrotropes. Thyroid. 1992; 2(1):31-8. PMID: 1381977.
      View in: PubMed
    20. Sarapura VD, Wood WM, Gordon DF, Ocran KW, Kao MY, Ridgway EC. Thyrotrope expression and thyroid hormone inhibition map to different regions of the mouse glycoprotein hormone alpha-subunit gene promoter. Endocrinology. 1990 Sep; 127(3):1352-61. PMID: 1696883.
      View in: PubMed
    21. Gordon DF, Wood WM, Ocran KW, Kao MY, Sarapura VD, Ridgway EC. TSH subunit gene promoters from a murine alpha-subunit producing tumor function normally. Mol Cell Endocrinol. 1990 Jun 18; 71(2):93-103. PMID: 2376287.
      View in: PubMed
    22. Ocran KW, Sarapura VD, Wood WM, Gordon DF, Gutierrez-Hartmann A, Ridgway EC. Identification of cis-acting promoter elements important for expression of the mouse glycoprotein hormone alpha-subunit gene in thyrotropes. Mol Endocrinol. 1990 May; 4(5):766-72. PMID: 1703276.
      View in: PubMed
    23. Ridgway EC, Gordon DF, Kao M, Sarapura V, Ocran K, Alexander L, Wood WM. Transcriptional regulation of the murine TSH subunit genes. Horm Metab Res Suppl. 1990; 23:5-9. PMID: 2210633.
      View in: PubMed
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