 Mitochondria, Liver
"Mitochondria, Liver" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mitochondria in hepatocytes. As in all mitochondria, there are an outer membrane and an inner membrane, together creating two separate mitochondrial compartments: the internal matrix space and a much narrower intermembrane space. In the liver mitochondrion, an estimated 67% of the total mitochondrial proteins is located in the matrix. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p343-4)
| Descriptor ID |
D008930
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| MeSH Number(s) |
A11.284.430.214.190.875.564.461 A11.284.835.626.461
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| Concept/Terms |
Mitochondria, Liver- Mitochondria, Liver
- Liver Mitochondria
- Liver Mitochondrion
- Mitochondrion, Liver
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Below are MeSH descriptors whose meaning is more general than "Mitochondria, Liver".
Below are MeSH descriptors whose meaning is more specific than "Mitochondria, Liver".
This graph shows the total number of publications written about "Mitochondria, Liver" by people in this website by year, and whether "Mitochondria, Liver" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 1 | 3 | | 1998 | 3 | 1 | 4 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 | | 2002 | 2 | 0 | 2 | | 2003 | 1 | 1 | 2 | | 2004 | 2 | 3 | 5 | | 2005 | 1 | 2 | 3 | | 2006 | 0 | 2 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 2 | 0 | 2 | | 2013 | 3 | 1 | 4 | | 2014 | 1 | 1 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 | | 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Mitochondria, Liver" by people in Profiles.
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Walker EM, Pearson GL, Lawlor N, Stendahl AM, Lietzke A, Sidarala V, Zhu J, Stromer T, Reck EC, Li J, Levi-D'Ancona E, Pasmooij MB, Hubers DL, Renberg A, Mohamed K, Parekh VS, Zhang IX, Thompson B, Zhang D, Ware SA, Haataja L, Qi N, Parker SCJ, Arvan P, Yin L, Kaufman BA, Satin LS, Sussel L, Stitzel ML, Soleimanpour SA. Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues. Science. 2025 04 11; 388(6743):eadf2034.
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Pratap A, Monge KM, Qualman AC, Kovacs EJ, Idrovo JP. Burn-induced mitochondrial dysfunction in hepatocytes: The role of methylation-controlled J protein silencing. J Trauma Acute Care Surg. 2025 Feb 01; 98(2):204-211.
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Fuller KNZ, McCoin CS, Von Schulze AT, Houchen CJ, Choi MA, Thyfault JP. Estradiol treatment or modest exercise improves hepatic health and mitochondrial outcomes in female mice following ovariectomy. Am J Physiol Endocrinol Metab. 2021 06 01; 320(6):E1020-E1031.
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Rozance PJ, Jones AK, Bourque SL, D'Alessandro A, Hay WW, Brown LD, Wesolowski SR. Effects of chronic hyperinsulinemia on metabolic pathways and insulin signaling in the fetal liver. Am J Physiol Endocrinol Metab. 2020 10 01; 319(4):E721-E733.
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McCoin CS, Von Schulze A, Allen J, Fuller KNZ, Xia Q, Koestler DC, Houchen CJ, Maurer A, Dorn GW, Shankar K, Morris EM, Thyfault JP. Sex modulates hepatic mitochondrial adaptations to high-fat diet and physical activity. Am J Physiol Endocrinol Metab. 2019 08 01; 317(2):E298-E311.
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Baker PR, Friedman JE. Mitochondrial role in the neonatal predisposition to developing nonalcoholic fatty liver disease. J Clin Invest. 2018 08 31; 128(9):3692-3703.
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Panasevich MR, Schuster CM, Phillips KE, Meers GM, Chintapalli SV, Wankhade UD, Shankar K, Butteiger DN, Krul ES, Thyfault JP, Rector RS. Soy compared with milk protein in a Western diet changes fecal microbiota and decreases hepatic steatosis in obese OLETF rats. J Nutr Biochem. 2017 08; 46:125-136.
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Sullivan EM, Fix A, Crouch MJ, Sparagna GC, Zeczycki TN, Brown DA, Shaikh SR. Murine diet-induced obesity remodels cardiac and liver mitochondrial phospholipid acyl chains with differential effects on respiratory enzyme activity. J Nutr Biochem. 2017 07; 45:94-103.
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Morris EM, Meers GM, Koch LG, Britton SL, Fletcher JA, Fu X, Shankar K, Burgess SC, Ibdah JA, Rector RS, Thyfault JP. Aerobic capacity and hepatic mitochondrial lipid oxidation alters susceptibility for chronic high-fat diet-induced hepatic steatosis. Am J Physiol Endocrinol Metab. 2016 10 01; 311(4):E749-E760.
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Go YM, Roede JR, Orr M, Liang Y, Jones DP. Integrated redox proteomics and metabolomics of mitochondria to identify mechanisms of cd toxicity. Toxicol Sci. 2014 May; 139(1):59-73.
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