 Genetic Vectors
"Genetic Vectors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.
| Descriptor ID |
D005822
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| MeSH Number(s) |
G05.360.337
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| Concept/Terms |
Genetic Vectors- Genetic Vectors
- Genetic Vector
- Vector, Genetic
- Vectors, Genetic
Shuttle Vectors- Shuttle Vectors
- Shuttle Vector
- Vector, Shuttle
- Vectors, Shuttle
Cloning Vectors- Cloning Vectors
- Cloning Vector
- Vector, Cloning
- Vectors, Cloning
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Below are MeSH descriptors whose meaning is more general than "Genetic Vectors".
Below are MeSH descriptors whose meaning is more specific than "Genetic Vectors".
This graph shows the total number of publications written about "Genetic Vectors" by people in this website by year, and whether "Genetic Vectors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 6 | 6 | | 1994 | 1 | 5 | 6 | | 1995 | 3 | 2 | 5 | | 1996 | 5 | 3 | 8 | | 1997 | 1 | 3 | 4 | | 1998 | 3 | 8 | 11 | | 1999 | 1 | 2 | 3 | | 2000 | 3 | 7 | 10 | | 2001 | 6 | 10 | 16 | | 2002 | 2 | 4 | 6 | | 2003 | 5 | 11 | 16 | | 2004 | 8 | 11 | 19 | | 2005 | 2 | 11 | 13 | | 2006 | 2 | 5 | 7 | | 2007 | 1 | 6 | 7 | | 2008 | 4 | 13 | 17 | | 2009 | 4 | 3 | 7 | | 2010 | 0 | 5 | 5 | | 2011 | 5 | 6 | 11 | | 2012 | 6 | 4 | 10 | | 2013 | 2 | 8 | 10 | | 2014 | 3 | 3 | 6 | | 2015 | 0 | 5 | 5 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 5 | 7 | | 2018 | 0 | 7 | 7 | | 2019 | 3 | 2 | 5 | | 2020 | 0 | 6 | 6 | | 2021 | 3 | 3 | 6 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genetic Vectors" by people in Profiles.
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Vignal-Clermont C, Yu-Wai-Man P, Newman NJ, Carelli V, Moster ML, Biousse V, Subramanian PS, Wang AG, Donahue SP, Leroy BP, Sadun AA, Klopstock T, Sergott RC, Rebolleda Fernandez G, Chwalisz BK, Banik R, Taiel M, Roux M, Sahel JA. Safety of Lenadogene Nolparvovec Gene Therapy Over 5 Years in 189 Patients With Leber Hereditary Optic Neuropathy. Am J Ophthalmol. 2023 05; 249:108-125.
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Bates EA, Counsell JR, Alizert S, Baker AT, Suff N, Boyle A, Bradshaw AC, Waddington SN, Nicklin SA, Baker AH, Parker AL. In Vitro and In Vivo Evaluation of Human Adenovirus Type 49 as a Vector for Therapeutic Applications. Viruses. 2021 07 28; 13(8).
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McMackin EAW, Corley JM, Karash S, Marden J, Wolfgang MC, Yahr TL. Cautionary Notes on the Use of Arabinose- and Rhamnose-Inducible Expression Vectors in Pseudomonas aeruginosa. J Bacteriol. 2021 07 22; 203(16):e0022421.
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Rindler TN, Brown KM, Stockman CA, van Lieshout LP, Martin EP, Weaver TE, Zacharias WJ, Wootton SK, Whitsett JA, Bridges JP. Efficient Transduction of Alveolar Type 2 Cells with Adeno-associated Virus for the Study of Lung Regeneration. Am J Respir Cell Mol Biol. 2021 07; 65(1):118-121.
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Srivastava A, Mallela KMG, Deorkar N, Brophy G. Manufacturing Challenges and Rational Formulation Development for AAV Viral Vectors. J Pharm Sci. 2021 07; 110(7):2609-2624.
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Powers JM, Haese NN, Denton M, Ando T, Kreklywich C, Bonin K, Streblow CE, Kreklywich N, Smith P, Broeckel R, DeFilippis V, Morrison TE, Heise MT, Streblow DN. Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses. PLoS Negl Trop Dis. 2021 04; 15(4):e0009308.
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Baker AT, Davies JA, Bates EA, Moses E, Mundy RM, Marlow G, Cole DK, Bliss CM, Rizkallah PJ, Parker AL. The Fiber Knob Protein of Human Adenovirus Type 49 Mediates Highly Efficient and Promiscuous Infection of Cancer Cell Lines Using a Novel Cell Entry Mechanism. J Virol. 2021 01 28; 95(4).
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Alnaas AA, Watson-Siriboe A, Tran S, Negussie M, Henderson JA, Osterberg JR, Chon NL, Harrott BM, Oviedo J, Lyakhova T, Michel C, Reisdorph N, Reisdorph R, Shearn CT, Lin H, Knight JD. Multivalent lipid targeting by the calcium-independent C2A domain of synaptotagmin-like protein 4/granuphilin. J Biol Chem. 2021 Jan-Jun; 296:100159.
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van Lieshout LP, Stegelmeier AA, Rindler TN, Lawder JJ, Sorensen DL, Frost KL, Booth SA, Bridges JP, Wootton SK. Engineered AAV8 capsid acquires heparin and AVB sepharose binding capacity but has altered in vivo transduction efficiency. Gene Ther. 2023 04; 30(3-4):236-244.
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Liu J, Xue Z, Zhang Y, Vann KR, Shi X, Kutateladze TG. Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1. Structure. 2020 11 03; 28(11):1225-1230.e3.
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