 Melitten
"Melitten" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Basic polypeptide from the venom of the honey bee (Apis mellifera). It contains 26 amino acids, has cytolytic properties, causes contracture of muscle, releases histamine, and disrupts surface tension, probably due to lysis of cell and mitochondrial membranes.
| Descriptor ID |
D008555
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| MeSH Number(s) |
D12.644.050.550 D12.776.543.695.054.550 D20.888.065.115.580 D23.946.833.065.115.580
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Melitten".
Below are MeSH descriptors whose meaning is more specific than "Melitten".
This graph shows the total number of publications written about "Melitten" by people in this website by year, and whether "Melitten" was a major or minor topic of these publications.
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Below are the most recent publications written about "Melitten" by people in Profiles.
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Houston ME, Kondejewski LH, Karunaratne DN, Gough M, Fidai S, Hodges RS, Hancock RE. Influence of preformed alpha-helix and alpha-helix induction on the activity of cationic antimicrobial peptides. J Pept Res. 1998 Aug; 52(2):81-8.
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Duke RC, Witter RZ, Nash PB, Young JD, Ojcius DM. Cytolysis mediated by ionophores and pore-forming agents: role of intracellular calcium in apoptosis. FASEB J. 1994 Feb; 8(2):237-46.
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Blechner SL, Olah GA, Strynadka NC, Hodges RS, Trewhella J. 4Ca2+.troponin C forms dimers in solution at neutral pH that dissociate upon binding various peptides: small-angle X-ray scattering studies of peptide-induced structural changes. Biochemistry. 1992 Nov 24; 31(46):11326-34.
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Zeitler P, Wu YQ, Handwerger S. Melittin stimulates phosphoinositide hydrolysis and placental lactogen release: arachidonic acid as a link between phospholipase A2 and phospholipase C signal-transduction pathways. Life Sci. 1991; 48(21):2089-95.
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Osorio e Castro VR, Ashwood ER, Wood SG, Vernon LP. Hemolysis of erythrocytes and fluorescence polarization changes elicited by peptide toxins, aliphatic alcohols, related glycols and benzylidene derivatives. Biochim Biophys Acta. 1990 Nov 16; 1029(2):252-8.
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