alpha-Crystallin B Chain
"alpha-Crystallin B Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY. Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME and ALEXANDER DISEASE.
Descriptor ID |
D038203
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MeSH Number(s) |
D12.776.306.366.100.300 D12.776.580.157.300
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Concept/Terms |
alpha-Crystallin B Chain- alpha-Crystallin B Chain
- B Chain, alpha-Crystallin
- alpha Crystallin B Chain
- Rosenthal Fiber Component
- alpha-Crystallin, B Subunit
- B Subunit alpha-Crystallin
- alpha Crystallin, B Subunit
- alpha B-Crystallin
- alpha B Crystallin
- Crystallins, alpha B Chain
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Below are MeSH descriptors whose meaning is more general than "alpha-Crystallin B Chain".
Below are MeSH descriptors whose meaning is more specific than "alpha-Crystallin B Chain".
This graph shows the total number of publications written about "alpha-Crystallin B Chain" by people in this website by year, and whether "alpha-Crystallin B Chain" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 0 | 1 | 2004 | 1 | 1 | 2 | 2005 | 1 | 0 | 1 | 2007 | 1 | 0 | 1 | 2011 | 0 | 1 | 1 | 2012 | 1 | 0 | 1 | 2013 | 3 | 0 | 3 | 2014 | 0 | 1 | 1 | 2015 | 1 | 0 | 1 | 2018 | 1 | 0 | 1 | 2019 | 2 | 0 | 2 | 2020 | 1 | 0 | 1 | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "alpha-Crystallin B Chain" by people in Profiles.
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Upadhyay AK, Mueller NH, Petrash JM, Kompella UB. Nano-assemblies enhance chaperone activity, stability, and delivery of alpha B-crystallin-D3 (aB-D3). J Control Release. 2022 12; 352:411-421.
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Nandi SK, Rankenberg J, Glomb MA, Nagaraj RH. Transient elevation of temperature promotes cross-linking of a-crystallin-client proteins through formation of advanced glycation endproducts: A potential role in presbyopia and cataracts. Biochem Biophys Res Commun. 2020 12 17; 533(4):1352-1358.
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Nandi SK, Rakete S, Nahomi RB, Michel C, Dunbar A, Fritz KS, Nagaraj RH. Succinylation Is a Gain-of-Function Modification in Human Lens aB-Crystallin. Biochemistry. 2019 03 05; 58(9):1260-1274.
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Nahomi RB, Nandi SK, Nagaraj RH. A monoclonal antibody targeted to the functional peptide of aB-crystallin inhibits the chaperone and anti-apoptotic activities. J Immunol Methods. 2019 04; 467:37-47.
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Droho S, Keener ME, Mueller NH. Heparan sulfate mediates cell uptake of aB-crystallin fused to the glycoprotein C cell penetration peptide. Biochim Biophys Acta Mol Cell Res. 2018 Apr; 1865(4):598-604.
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Mueller NH, Fogueri U, Pedler MG, Montana K, Petrash JM, Ammar DA. Impact of Subunit Composition on the Uptake of a-Crystallin by Lens and Retina. PLoS One. 2015; 10(9):e0137659.
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Panda AK, Nandi SK, Chakraborty A, Nagaraj RH, Biswas A. Differential role of arginine mutations on the structure and functions of a-crystallin. Biochim Biophys Acta. 2016 Jan; 1860(1 Pt B):199-210.
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Nandi SK, Chakraborty A, Panda AK, Ray SS, Kar RK, Bhunia A, Biswas A. Interaction of ATP with a small heat shock protein from Mycobacterium leprae: effect on its structure and function. PLoS Negl Trop Dis. 2015 Mar; 9(3):e0003661.
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McLendon PM, Ferguson BS, Osinska H, Bhuiyan MS, James J, McKinsey TA, Robbins J. Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy. Proc Natl Acad Sci U S A. 2014 Dec 02; 111(48):E5178-86.
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Bellaye PS, Wettstein G, Burgy O, Besnard V, Joannes A, Colas J, Causse S, Marchal-Somme J, Fabre A, Crestani B, Kolb M, Gauldie J, Camus P, Garrido C, Bonniaud P. The small heat-shock protein aB-crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis. J Pathol. 2014 Mar; 232(4):458-72.
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