E2F3 Transcription Factor
"E2F3 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A. E2F3 regulates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis.
Descriptor ID |
D050699
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MeSH Number(s) |
D12.776.930.211.750
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Concept/Terms |
E2F3 Transcription Factor- E2F3 Transcription Factor
- Transcription Factor, E2F3
- Transcription Factor E2F-3
- E2F-3, Transcription Factor
- Transcription Factor E2F 3
- E2F Transcription Factor 3 Protein
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Below are MeSH descriptors whose meaning is more general than "E2F3 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F3 Transcription Factor".
This graph shows the total number of publications written about "E2F3 Transcription Factor" by people in this website by year, and whether "E2F3 Transcription Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 | 1998 | 0 | 1 | 1 | 2002 | 0 | 2 | 2 | 2009 | 1 | 0 | 1 | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "E2F3 Transcription Factor" by people in Profiles.
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Nakajima R, Deguchi R, Komori H, Zhao L, Zhou Y, Shirasawa M, Angelina A, Goto Y, Tohjo F, Nakahashi K, Nakata K, Iwanaga R, Bradford AP, Araki K, Warita T, Ohtani K. The TFDP1 gene coding for DP1, the heterodimeric partner of the transcription factor E2F, is a target of deregulated E2F. Biochem Biophys Res Commun. 2023 06 30; 663:154-162.
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Major JL, Salih M, Tuana BS. E2F6 protein levels modulate drug induced apoptosis in cardiomyocytes. Cell Signal. 2017 12; 40:230-238.
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Rempel RE, Mori S, Gasparetto M, Glozak MA, Andrechek ER, Adler SB, Laakso NM, Lagoo AS, Storms R, Smith C, Nevins JR. A role for E2F activities in determining the fate of Myc-induced lymphomagenesis. PLoS Genet. 2009 Sep; 5(9):e1000640.
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DeGregori J. The genetics of the E2F family of transcription factors: shared functions and unique roles. Biochim Biophys Acta. 2002 Jun 21; 1602(2):131-50.
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Tyagi A, Agarwal C, Agarwal R. Inhibition of retinoblastoma protein (Rb) phosphorylation at serine sites and an increase in Rb-E2F complex formation by silibinin in androgen-dependent human prostate carcinoma LNCaP cells: role in prostate cancer prevention. Mol Cancer Ther. 2002 May; 1(7):525-32.
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Leone G, DeGregori J, Yan Z, Jakoi L, Ishida S, Williams RS, Nevins JR. E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev. 1998 Jul 15; 12(14):2120-30.
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DeGregori J, Leone G, Miron A, Jakoi L, Nevins JR. Distinct roles for E2F proteins in cell growth control and apoptosis. Proc Natl Acad Sci U S A. 1997 Jul 08; 94(14):7245-50.
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