 Myofibroblasts
"Myofibroblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Spindle-shaped cells with characteristic CONTRACTILE PROTEINS and structures that contribute to the WOUND HEALING process. They occur in GRANULATION TISSUE and also in pathological processes such as FIBROSIS.
| Descriptor ID |
D058628
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| MeSH Number(s) |
A11.329.228.975 A11.620.520.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Myofibroblasts".
Below are MeSH descriptors whose meaning is more specific than "Myofibroblasts".
This graph shows the total number of publications written about "Myofibroblasts" by people in this website by year, and whether "Myofibroblasts" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 1 | 2 | | 2011 | 3 | 1 | 4 | | 2012 | 2 | 1 | 3 | | 2014 | 2 | 3 | 5 | | 2015 | 4 | 0 | 4 | | 2016 | 3 | 3 | 6 | | 2017 | 6 | 2 | 8 | | 2018 | 3 | 5 | 8 | | 2019 | 4 | 2 | 6 | | 2020 | 4 | 1 | 5 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myofibroblasts" by people in Profiles.
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Gonzalez Rodriguez A, Schroeder ME, Grim JC, Walker CJ, Speckl KF, Weiss RM, Anseth KS. Tumor necrosis factor-a promotes and exacerbates calcification in heart valve myofibroblast populations. FASEB J. 2021 03; 35(3):e21382.
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Lu S, Jolly AJ, Strand KA, Dubner AM, Mutryn MF, Moulton KS, Nemenoff RA, Majesky MW, Weiser-Evans MC. Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis. JCI Insight. 2020 12 03; 5(23).
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Grim JC, Aguado BA, Vogt BJ, Batan D, Andrichik CL, Schroeder ME, Gonzalez-Rodriguez A, Yavitt FM, Weiss RM, Anseth KS. Secreted Factors From Proinflammatory Macrophages Promote an Osteoblast-Like Phenotype in Valvular Interstitial Cells. Arterioscler Thromb Vasc Biol. 2020 11; 40(11):e296-e308.
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Ceccato TL, Starbuck RB, Hall JK, Walker CJ, Brown TE, Killgore JP, Anseth KS, Leinwand LA. Defining the Cardiac Fibroblast Secretome in a Fibrotic Microenvironment. J Am Heart Assoc. 2020 10 20; 9(19):e017025.
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Dwivedi N, Tao S, Jamadar A, Sinha S, Howard C, Wallace DP, Fields TA, Leask A, Calvet JP, Rao R. Epithelial Vasopressin Type-2 Receptors Regulate Myofibroblasts by a YAP-CCN2-Dependent Mechanism in Polycystic Kidney Disease. J Am Soc Nephrol. 2020 08; 31(8):1697-1710.
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Shook BA, Wasko RR, Mano O, Rutenberg-Schoenberg M, Rudolph MC, Zirak B, Rivera-Gonzalez GC, López-Giráldez F, Zarini S, Rezza A, Clark DA, Rendl M, Rosenblum MD, Gerstein MB, Horsley V. Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair. Cell Stem Cell. 2020 06 04; 26(6):880-895.e6.
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Welk V, Meul T, Lukas C, Kammerl IE, Mulay SR, Schamberger AC, Semren N, Fernandez IE, Anders HJ, Günther A, Behr J, Eickelberg O, Korfei M, Meiners S. Proteasome activator PA200 regulates myofibroblast differentiation. Sci Rep. 2019 10 23; 9(1):15224.
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Blackmon AM, Como CN, Bubak AN, Mescher T, Jones D, Nagel MA. Varicella Zoster Virus Alters Expression of Cell Adhesion Proteins in Human Perineurial Cells via Interleukin 6. J Infect Dis. 2019 09 26; 220(9):1453-1461.
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Aguado BA, Schuetze KB, Grim JC, Walker CJ, Cox AC, Ceccato TL, Tan AC, Sucharov CC, Leinwand LA, Taylor MRG, McKinsey TA, Anseth KS. Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation. Sci Transl Med. 2019 09 11; 11(509).
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Sitaraman S, Na CL, Yang L, Filuta A, Bridges JP, Weaver TE. Proteasome dysfunction in alveolar type 2 epithelial cells is associated with acute respiratory distress syndrome. Sci Rep. 2019 08 29; 9(1):12509.
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