 Hepatocytes
"Hepatocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The main structural component of the LIVER. They are specialized EPITHELIAL CELLS that are organized into interconnected plates called lobules.
| Descriptor ID |
D022781
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| MeSH Number(s) |
A11.436.348
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| Concept/Terms |
Hepatocytes- Hepatocytes
- Hepatocyte
- Hepatic Cells
- Cell, Hepatic
- Cells, Hepatic
- Hepatic Cell
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Below are MeSH descriptors whose meaning is more general than "Hepatocytes".
Below are MeSH descriptors whose meaning is more specific than "Hepatocytes".
This graph shows the total number of publications written about "Hepatocytes" by people in this website by year, and whether "Hepatocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 2 | 3 | | 2002 | 3 | 4 | 7 | | 2003 | 2 | 0 | 2 | | 2004 | 3 | 3 | 6 | | 2005 | 6 | 2 | 8 | | 2006 | 8 | 1 | 9 | | 2007 | 2 | 1 | 3 | | 2008 | 2 | 3 | 5 | | 2009 | 4 | 1 | 5 | | 2010 | 2 | 5 | 7 | | 2011 | 4 | 3 | 7 | | 2012 | 3 | 6 | 9 | | 2013 | 5 | 1 | 6 | | 2014 | 0 | 7 | 7 | | 2015 | 2 | 2 | 4 | | 2016 | 4 | 6 | 10 | | 2017 | 1 | 3 | 4 | | 2018 | 2 | 4 | 6 | | 2019 | 2 | 2 | 4 | | 2020 | 0 | 8 | 8 | | 2021 | 2 | 3 | 5 | | 2022 | 0 | 5 | 5 | | 2023 | 0 | 6 | 6 | | 2024 | 0 | 4 | 4 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Hepatocytes" by people in Profiles.
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Walker EM, Pearson GL, Lawlor N, Stendahl AM, Lietzke A, Sidarala V, Zhu J, Stromer T, Reck EC, Li J, Levi-D'Ancona E, Pasmooij MB, Hubers DL, Renberg A, Mohamed K, Parekh VS, Zhang IX, Thompson B, Zhang D, Ware SA, Haataja L, Qi N, Parker SCJ, Arvan P, Yin L, Kaufman BA, Satin LS, Sussel L, Stitzel ML, Soleimanpour SA. Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues. Science. 2025 04 11; 388(6743):eadf2034.
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Pratap A, Monge KM, Qualman AC, Kovacs EJ, Idrovo JP. Burn-induced mitochondrial dysfunction in hepatocytes: The role of methylation-controlled J protein silencing. J Trauma Acute Care Surg. 2025 Feb 01; 98(2):204-211.
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Andres-Hernando A, Orlicky DJ, Kuwabara M, Fini MA, Tolan DR, Johnson RJ, Lanaspa MA. Activation of AMPD2 drives metabolic dysregulation and liver disease in mice with hereditary fructose intolerance. Commun Biol. 2024 07 11; 7(1):849.
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Brown LD, Rozance PJ, Wang D, Eroglu EC, Wilkening RB, Solmonson A, Wesolowski SR. Increased hepatic glucose production with lower oxidative metabolism in the growth-restricted fetus. JCI Insight. 2024 Apr 30; 9(10).
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Yousof TR, Bouchard CC, Alb M, Lynn EG, Lhot?k S, Jiang H, MacDonald M, Li H, Byun JH, Makda Y, Athanasopoulos M, Maclean KN, Cherrington NJ, Naqvi A, Igdoura SA, Krepinsky JC, Steinberg GR, Austin RC. Restoration of the ER stress response protein TDAG51 in hepatocytes mitigates NAFLD in mice. J Biol Chem. 2024 02; 300(2):105655.
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Grayck MR, McCarthy WC, Solar M, Golden E, Balasubramaniyan N, Zheng L, Sherlock LG, Wright CJ. GSK3?/NF-?B -dependent transcriptional regulation of homeostatic hepatocyte Tnf production. Am J Physiol Gastrointest Liver Physiol. 2024 Apr 01; 326(4):G374-G384.
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Karpova Y, Orlicky DJ, Schmidt EE, Tulin AV. Disrupting Poly(ADP-ribosyl)ating Pathway Creates Premalignant Conditions in Mammalian Liver. Int J Mol Sci. 2023 Dec 06; 24(24).
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Swenson KS, Wang D, Jones AK, Nash MJ, O'Rourke R, Takahashi DL, Kievit P, Hennebold JD, Aagaard KM, Friedman JE, Jones KL, Rozance PJ, Brown LD, Wesolowski SR. Metformin Disrupts Signaling and Metabolism in Fetal Hepatocytes. Diabetes. 2023 09 01; 72(9):1214-1227.
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Fern?ndez Moro C, Geyer N, Harrizi S, Hamidi Y, S?derqvist S, Kuznyecov D, Tidholm Qvist E, Salmonson Schaad M, Hermann L, Lindberg A, Heuchel RL, Mart?n-Bernab? A, Dhanjal S, Navis AC, Villard C, Del Valle AC, Boz?ky L, Sparrelid E, Dirix L, Strell C, ?stman A, Schmierer B, Vermeulen PB, Engstrand J, Boz?ky B, Gerling M. An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver. Nat Commun. 2023 08 18; 14(1):5024.
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Feng D, Xiang X, Guan Y, Guillot A, Lu H, Chang C, He Y, Wang H, Pan H, Ju C, Colgan SP, Tacke F, Wang XW, Kunos G, Gao B. Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models. J Clin Invest. 2023 08 01; 133(15).
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