Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Ryan Michael Sheridan

TitleSenior Research Scientist
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BioChem&Molecular Genetics

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Erickson B, Fedoryshchak R, Fong N, Sheridan R, Larson KY, Saviola AJ, Mouilleron S, Hansen KC, Treisman R, Bentley DL. PP1/PNUTS phosphatase binds the restrictor complex and stimulates RNA Pol II transcription termination. Cell Rep. 2025 May 27; 44(5):115564. PMID: 40244850.
      View in: PubMed
    2. Valen?a-Pereira F, Sheridan RM, Riemondy KA, Thornton T, Fang Q, Barret B, Paludo G, Thompson C, Collins P, Santiago M, Oltz E, Rincon M. Inactivation of GSK3? by Ser389 phosphorylation prevents thymocyte necroptosis and impacts Tcr repertoire diversity. Cell Death Differ. 2025 May; 32(5):880-898. PMID: 39779909.
      View in: PubMed
    3. Tamburini B, Sheridan R, Doan T, Lucas C, Forward T, Fleming I, Uecker-Martin A, Morrison T, Hesselberth J. A specific gene expression program underlies antigen archiving by lymphatic endothelial cells in mammalian lymph nodes. Res Sq. 2024 Dec 10. PMID: 39711554.
      View in: PubMed
    4. Blears D, Lou J, Fong N, Mitter R, Sheridan RM, He D, Dirac-Svejstrup AB, Bentley D, Svejstrup JQ. Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint. Mol Cell. 2024 Dec 19; 84(24):4790-4807.e11. PMID: 39504960.
      View in: PubMed
    5. Martinez A, Stemm-Wolf AJ, Sheridan RM, Taliaferro MJ, Pearson CG. The Unkempt RNA binding protein reveals a local translation program in centriole overduplication. bioRxiv. 2024 Jul 30. PMID: 39131325.
      View in: PubMed
    6. Sheridan RM, Doan TA, Lucas C, Forward TS, Uecker-Martin A, Morrison TE, Hesselberth JR, Tamburini BAJ. A specific and portable gene expression program underlies antigen archiving by lymphatic endothelial cells. bioRxiv. 2024 Apr 02. PMID: 38617225.
      View in: PubMed
    7. Lucas CJ, Sheridan RM, Reynoso GV, Davenport BJ, McCarthy MK, Martin A, Hesselberth JR, Hickman HD, Tamburini BA, Morrison TE. Chikungunya virus infection disrupts lymph node lymphatic endothelial cell composition and function via MARCO. JCI Insight. 2024 Jan 09; 9(4). PMID: 38194268.
      View in: PubMed
    8. Lucas CJ, Sheridan RM, Reynoso GV, Davenport BJ, McCarthy MK, Martin A, Hesselberth JR, Hickman HD, Tamburini BAJ, Morrison TE. Chikungunya virus infection disrupts lymph node lymphatic endothelial cell composition and function via MARCO. bioRxiv. 2023 Oct 13. PMID: 37873393.
      View in: PubMed
    9. Kim YK, Walters JA, Moss ND, Wells KL, Sheridan R, Miranda JG, Benninger RKP, Pyle LL, O'Brien RM, Sussel L, Davidson HW. Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration. Mol Metab. 2022 12; 66:101632. PMID: 36347424.
      View in: PubMed
    10. Fong N, Sheridan RM, Ramachandran S, Bentley DL. The pausing zone and control of RNA polymerase II elongation by Spt5: Implications for the pause-release model. Mol Cell. 2022 10 06; 82(19):3632-3645.e4. PMID: 36206739.
      View in: PubMed
    11. Peterson JN, Boackle SA, Taitano SH, Sang A, Lang J, Kelly M, Rahkola JT, Miranda AM, Sheridan RM, Thurman JM, Rao VK, Torres RM, Pelanda R. Elevated Detection of Dual Antibody B Cells Identifies Lupus Patients With B Cell-Reactive VH4-34 Autoantibodies. Front Immunol. 2022; 13:795209. PMID: 35185888.
      View in: PubMed
    12. Bilodeau DY, Sheridan RM, Balan B, Jex AR, Rissland OS. Precise gene models using long-read sequencing reveal a unique poly(A) signal in Giardia lamblia. RNA. 2022 05; 28(5):668-682. PMID: 35110372.
      View in: PubMed
    13. Carpentier KS, Sheridan RM, Lucas CJ, Davenport BJ, Li FS, Lucas ED, McCarthy MK, Reynoso GV, May NA, Tamburini BAJ, Hesselberth JR, Hickman HD, Morrison TE. MARCO+ lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination. EMBO J. 2021 11 15; 40(22):e108966. PMID: 34618370.
      View in: PubMed
    14. Stemm-Wolf AJ, O'Toole ET, Sheridan RM, Morgan JT, Pearson CG. The SON RNA splicing factor is required for intracellular trafficking structures that promote centriole assembly and ciliogenesis. Mol Biol Cell. 2021 10 01; 32(20):ar4. PMID: 34406792.
      View in: PubMed
    15. Walsh SM, Sheridan RM, Lucas ED, Doan TA, Ware BC, Schafer J, Fu R, Burchill MA, Hesselberth JR, Tamburini BAJ. Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node. Elife. 2021 04 12; 10. PMID: 33843587.
      View in: PubMed
    16. Summers ME, Richmond BW, Menon S, Sheridan RM, Kropski JA, Majka SA, Taketo MM, Bastarache JA, West JD, De Langhe S, Geraghty P, Klemm DJ, Chu HW, Friedman RS, Tao YK, Foronjy RF, Majka SM. Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of canonical Wnt signaling. FASEB J. 2020 08; 34(8):10267-10285. PMID: 32533805.
      View in: PubMed
    17. Fu R, Gillen AE, Sheridan RM, Tian C, Daya M, Hao Y, Hesselberth JR, Riemondy KA. clustifyr: an R package for automated single-cell RNA sequencing cluster classification. F1000Res. 2020; 9:223. PMID: 32765839.
      View in: PubMed
    18. Pei S, Pollyea DA, Gustafson A, Stevens BM, Minhajuddin M, Fu R, Riemondy KA, Gillen AE, Sheridan RM, Kim J, Costello JC, Amaya ML, Inguva A, Winters A, Ye H, Krug A, Jones CL, Adane B, Khan N, Ponder J, Schowinsky J, Abbott D, Hammes A, Myers JR, Ashton JM, Nemkov T, D'Alessandro A, Gutman JA, Ramsey HE, Savona MR, Smith CA, Jordan CT. Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia. Cancer Discov. 2020 04; 10(4):536-551. PMID: 31974170.
      View in: PubMed
    19. Cortazar MA, Sheridan RM, Erickson B, Fong N, Glover-Cutter K, Brannan K, Bentley DL. Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a "Sitting Duck Torpedo" Mechanism. Mol Cell. 2019 12 19; 76(6):896-908.e4. PMID: 31677974.
      View in: PubMed
    20. Sheridan RM, Fong N, D'Alessandro A, Bentley DL. Widespread Backtracking by RNA Pol II Is a Major Effector of Gene Activation, 5' Pause Release, Termination, and Transcription Elongation Rate. Mol Cell. 2019 01 03; 73(1):107-118.e4. PMID: 30503775.
      View in: PubMed
    21. Erickson B, Sheridan RM, Cortazar M, Bentley DL. Dynamic turnover of paused Pol II complexes at human promoters. Genes Dev. 2018 09 01; 32(17-18):1215-1225. PMID: 30150253.
      View in: PubMed
    22. Riemondy KA, Sheridan RM, Gillen A, Yu Y, Bennett CG, Hesselberth JR. valr: Reproducible genome interval analysis in R. F1000Res. 2017; 6:1025. PMID: 28751969.
      View in: PubMed
    23. Fong N, Saldi T, Sheridan RM, Cortazar MA, Bentley DL. RNA Pol II Dynamics Modulate Co-transcriptional Chromatin Modification, CTD Phosphorylation, and Transcriptional Direction. Mol Cell. 2017 May 18; 66(4):546-557.e3. PMID: 28506463.
      View in: PubMed
    24. Saldi T, Cortazar MA, Sheridan RM, Bentley DL. Coupling of RNA Polymerase II Transcription Elongation with Pre-mRNA Splicing. J Mol Biol. 2016 06 19; 428(12):2623-2635. PMID: 27107644.
      View in: PubMed
    25. Sheridan RM, Bentley DL. Selectable one-step PCR-mediated integration of a degron for rapid depletion of endogenous human proteins. Biotechniques. 2016 Feb; 60(2):69-74. PMID: 26842351.
      View in: PubMed
    26. Ruehle MD, Zhang H, Sheridan RM, Mitra S, Chen Y, Gonzalez RL, Cooperman BS, Kieft JS. A dynamic RNA loop in an IRES affects multiple steps of elongation factor-mediated translation initiation. Elife. 2015 Nov 02; 4. PMID: 26523395.
      View in: PubMed
    27. Fong N, Brannan K, Erickson B, Kim H, Cortazar MA, Sheridan RM, Nguyen T, Karp S, Bentley DL. Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition. Mol Cell. 2015 Oct 15; 60(2):256-67. PMID: 26474067.
      View in: PubMed
    28. Li H, Sheridan R, Williams T. Analysis of TFAP2A mutations in Branchio-Oculo-Facial Syndrome indicates functional complexity within the AP-2a DNA-binding domain. Hum Mol Genet. 2013 Aug 15; 22(16):3195-206. PMID: 23578821.
      View in: PubMed
    Sheridan's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (163) concept(s)
    _
    Co-Authors Expand Description
    See all (40) people
    _
    Similar People Expand Description
    See all (60) people
    _
    Same Department Expand Description
    Search Department

    Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)