 Exoribonucleases
"Exoribonucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of enzymes that catalyze the exonucleolytic cleavage of RNA. It includes EC 3.1.13.-, EC 3.1.14.-, EC 3.1.15.-, and EC 3.1.16.-. EC 3.1.-
| Descriptor ID |
D005095
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| MeSH Number(s) |
D08.811.277.352.365.300 D08.811.277.352.700.375
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Exoribonucleases".
Below are MeSH descriptors whose meaning is more specific than "Exoribonucleases".
This graph shows the total number of publications written about "Exoribonucleases" by people in this website by year, and whether "Exoribonucleases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 2 | 2 | | 2008 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 3 | 1 | 4 | | 2014 | 1 | 1 | 2 | | 2015 | 4 | 0 | 4 | | 2016 | 3 | 0 | 3 | | 2017 | 1 | 0 | 1 | | 2018 | 3 | 0 | 3 |
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Below are the most recent publications written about "Exoribonucleases" by people in Profiles.
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Steckelberg AL, Vicens Q, Kieft JS. Exoribonuclease-Resistant RNAs Exist within both Coding and Noncoding Subgenomic RNAs. MBio. 2018 12 18; 9(6).
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Steckelberg AL, Akiyama BM, Costantino DA, Sit TL, Nix JC, Kieft JS. A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure. Proc Natl Acad Sci U S A. 2018 06 19; 115(25):6404-6409.
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MacFadden A, O'Donoghue Z, Silva PAGC, Chapman EG, Olsthoorn RC, Sterken MG, Pijlman GP, Bredenbeek PJ, Kieft JS. Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs. Nat Commun. 2018 01 09; 9(1):119.
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Shukla S, Parker R. PARN Modulates Y RNA Stability and Its 3'-End Formation. Mol Cell Biol. 2017 Oct 15; 37(20).
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Akiyama BM, Laurence HM, Massey AR, Costantino DA, Xie X, Yang Y, Shi PY, Nix JC, Beckham JD, Kieft JS. Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease. Science. 2016 12 02; 354(6316):1148-1152.
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Rowley PA, Ho B, Bushong S, Johnson A, Sawyer SL. XRN1 Is a Species-Specific Virus Restriction Factor in Yeasts. PLoS Pathog. 2016 Oct; 12(10):e1005890.
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Shukla S, Schmidt JC, Goldfarb KC, Cech TR, Parker R. Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects. Nat Struct Mol Biol. 2016 Apr; 23(4):286-92.
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Burris AM, Ballew BJ, Kentosh JB, Turner CE, Norton SA, Giri N, Alter BP, Nellan A, Gamper C, Hartman KR, Savage SA. Hoyeraal-Hreidarsson Syndrome due to PARN Mutations: Fourteen Years of Follow-Up. Pediatr Neurol. 2016 Mar; 56:62-68.e1.
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Fong N, Brannan K, Erickson B, Kim H, Cortazar MA, Sheridan RM, Nguyen T, Karp S, Bentley DL. Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition. Mol Cell. 2015 Oct 15; 60(2):256-67.
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Kieft JS, Rabe JL, Chapman EG. New hypotheses derived from the structure of a flaviviral Xrn1-resistant RNA: Conservation, folding, and host adaptation. RNA Biol. 2015; 12(11):1169-77.
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