 Macrolides
"Macrolides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.
| Descriptor ID |
D018942
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| MeSH Number(s) |
D02.540.505 D02.540.576.500 D04.345.674.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Macrolides".
Below are MeSH descriptors whose meaning is more specific than "Macrolides".
This graph shows the total number of publications written about "Macrolides" by people in this website by year, and whether "Macrolides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 2 | 2 | | 2012 | 2 | 2 | 4 | | 2013 | 1 | 2 | 3 | | 2014 | 0 | 1 | 1 | | 2015 | 3 | 0 | 3 | | 2016 | 2 | 3 | 5 | | 2017 | 5 | 1 | 6 | | 2018 | 2 | 0 | 2 | | 2019 | 6 | 0 | 6 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 2 | 3 | | 2022 | 0 | 2 | 2 | | 2023 | 0 | 2 | 2 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Macrolides" by people in Profiles.
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Chiu C-Y, Chastain DB, Salam ME, Sassine J, Henao-Mart?nez AF. Incidence of fidaxomicin allergy in patients with macrolide allergies: a large database analysis. Antimicrob Agents Chemother. 2025 Apr 02; 69(4):e0192424.
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Obafemi OA, Rowan SE, Nishiyama M, Wendel KA. Mycoplasma genitalium: Key Information for the Primary Care Clinician. Med Clin North Am. 2024 Mar; 108(2):297-310.
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Nguyen MH, Daley CL. Treatment of Mycobacterium avium Complex Pulmonary Disease: When Should I Treat and What Therapy Should I Start? Clin Chest Med. 2023 12; 44(4):771-783.
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Pinnell LJ, Kuiper G, Huebner KL, Doster E, Parker JK, Alekozai N, Powers JG, Wallen RL, Belk KE, Morley PS. More than an anthropogenic phenomenon: Antimicrobial resistance in ungulates from natural and agricultural environments. Sci Total Environ. 2023 Feb 01; 858(Pt 1):159789.
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Janas A, Pyta K, Gdaniec M, Przybylski P. An Approach to Modify 14-Membered Lactone Macrolide Antibiotic Scaffolds. J Org Chem. 2022 03 04; 87(5):3758-3761.
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Beale MA, Marks M, Cole MJ, Lee MK, Pitt R, Ruis C, Balla E, Crucitti T, Ewens M, Fern?ndez-Naval C, Grankvist A, Guiver M, Kenyon CR, Khairullin R, Kularatne R, Arando M, Molini BJ, Obukhov A, Page EE, Petrovay F, Rietmeijer C, Rowley D, Shokoples S, Smit E, Sweeney EL, Taiaroa G, Vera JH, Wenner?s C, Whiley DM, Williamson DA, Hughes G, Naidu P, Unemo M, Krajden M, Lukehart SA, Morshed MG, Fifer H, Thomson NR. Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis. Nat Microbiol. 2021 12; 6(12):1549-1560.
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Griffith DE, Daley CL. Treatment of Mycobacterium abscessus Pulmonary Disease. Chest. 2022 01; 161(1):64-75.
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Marras SAE, Chen L, Shashkina E, Davidson RM, Strong M, Daley CL, Kreiswirth BN. A Molecular-Beacon-Based Multiplex Real-Time PCR Assay To Distinguish Mycobacterium abscessus Subspecies and Determine Macrolide Susceptibility. J Clin Microbiol. 2021 07 19; 59(8):e0045521.
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Desai S, Hall M, Lipsett SC, Shah SS, Brogan TV, Hersh AL, Williams DJ, Grijalva CG, Gerber JS, Blaschke AJ, Neuman MI, Ambroggio L. Mycoplasma Pneumoniae Testing and Treatment Among Children With Community-Acquired Pneumonia. Hosp Pediatr. 2021 07; 11(7):760-763.
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Janas A, Pecyna P, Gajecka M, Bartl F, Przybylski P. Synthesis and Antibacterial Activity of New N-Alkylammonium and Carbonate-Triazole Derivatives within Desosamine of 14- and 15-Membered Lactone Macrolides. ChemMedChem. 2020 08 19; 15(16):1529-1551.
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