 Cross-Linking Reagents
"Cross-Linking Reagents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
| Descriptor ID |
D003432
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| MeSH Number(s) |
D27.720.470.410.210
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| Concept/Terms |
Cross-Linking Reagents- Cross-Linking Reagents
- Reagents, Cross-Linking
- Crosslinking Reagents
- Reagents, Crosslinking
- Bifunctional Reagents
- Reagents, Bifunctional
- Cross Linking Reagents
- Linking Reagents, Cross
- Reagents, Cross Linking
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Below are MeSH descriptors whose meaning is more general than "Cross-Linking Reagents".
Below are MeSH descriptors whose meaning is more specific than "Cross-Linking Reagents".
This graph shows the total number of publications written about "Cross-Linking Reagents" by people in this website by year, and whether "Cross-Linking Reagents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 | | 1996 | 1 | 7 | 8 | | 1997 | 0 | 4 | 4 | | 1998 | 0 | 6 | 6 | | 1999 | 2 | 4 | 6 | | 2000 | 0 | 3 | 3 | | 2001 | 1 | 6 | 7 | | 2002 | 1 | 6 | 7 | | 2003 | 0 | 4 | 4 | | 2004 | 1 | 6 | 7 | | 2005 | 0 | 5 | 5 | | 2006 | 2 | 2 | 4 | | 2007 | 0 | 2 | 2 | | 2008 | 3 | 7 | 10 | | 2009 | 4 | 5 | 9 | | 2010 | 3 | 3 | 6 | | 2011 | 0 | 3 | 3 | | 2012 | 0 | 11 | 11 | | 2013 | 0 | 7 | 7 | | 2014 | 1 | 4 | 5 | | 2015 | 0 | 3 | 3 | | 2016 | 0 | 4 | 4 | | 2017 | 1 | 2 | 3 | | 2018 | 3 | 5 | 8 | | 2019 | 1 | 0 | 1 | | 2020 | 2 | 4 | 6 | | 2021 | 0 | 2 | 2 | | 2024 | 0 | 2 | 2 | | 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Cross-Linking Reagents" by people in Profiles.
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Wei Z, Boateng NKK, Schmitt LR, Cline H, Fernandes Fonseca MT, Newberry A, Taylor A, Adelmeijer J, Poole LG, Stravitz RT, Lee WM, Lisman T, Hansen KC, Luyendyk JP. Integrated cross-linking by TG2 and FXIII generates hepatoprotective fibrin(ogen) deposits in injured liver. Blood. 2025 May 22; 145(21):2507-2517.
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Lee JS, Kirkpatrick BE, Dhand AP, Hibbard LP, Nelson BR, Skillin NP, Johnson MC, Batan D, Fairbanks BD, White TJ, Bowman CN, Burdick JA, Anseth KS. Photodegradable polyacrylamide tanglemers enable spatiotemporal control over chain lengthening in high-strength and low-hysteresis hydrogels. J Mater Chem B. 2025 Jan 15; 13(3):894-903.
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Bower BM, Curry SD, Goodwin AP, Cha JN. Photocrosslinkable, Low-Affinity Affibodies Show Improved Transport and Retention in 3D Tumor Spheroids. Biomacromolecules. 2024 Nov 11; 25(11):7511-7517.
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Jaeschke MW, Borelli AN, Skillin NP, White TJ, Anseth KS. Engineering a Hydrazone and Triazole Crosslinked Hydrogel for Extrusion-Based Printing and Cell Delivery. Adv Healthc Mater. 2024 Aug; 13(20):e2400062.
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Yang B, Wei K, Loebel C, Zhang K, Feng Q, Li R, Wong SHD, Xu X, Lau C, Chen X, Zhao P, Yin C, Burdick JA, Wang Y, Bian L. Enhanced mechanosensing of cells in synthetic 3D matrix with controlled biophysical dynamics. Nat Commun. 2021 06 10; 12(1):3514.
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Jarrell DK, Vanderslice EJ, Lennon ML, Lyons AC, VeDepo MC, Jacot JG. Increasing salinity of fibrinogen solvent generates stable fibrin hydrogels for cell delivery or tissue engineering. PLoS One. 2021; 16(5):e0239242.
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Nandi SK, Rankenberg J, Glomb MA, Nagaraj RH. Transient elevation of temperature promotes cross-linking of a-crystallin-client proteins through formation of advanced glycation endproducts: A potential role in presbyopia and cataracts. Biochem Biophys Res Commun. 2020 12 17; 533(4):1352-1358.
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Bram AI, Gouzman I, Bolker A, Eliaz N, Verker R. The Effect of POSS Type on the Shape Memory Properties of Epoxy-Based Nanocomposites. Molecules. 2020 Sep 14; 25(18).
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Locy ML, Rangarajan S, Yang S, Johnson MR, Bernard K, Kurundkar A, Bone NB, Zmijewski JW, Byun J, Pennathur S, Zhou Y, Thannickal VJ. Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration. Sci Signal. 2020 08 11; 13(644).
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Hodge J, Quint C. Tissue engineered vessel from a biodegradable electrospun scaffold stimulated with mechanical stretch. Biomed Mater. 2020 07 27; 15(5):055006.
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