Iron Chelating Agents
"Iron Chelating Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems.
Descriptor ID |
D007502
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MeSH Number(s) |
D27.505.519.914.500.410 D27.720.832.500.410
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Concept/Terms |
Iron Chelating Agents- Iron Chelating Agents
- Agents, Iron Chelating
- Chelating Agents, Iron
- Iron Chelates
- Chelates, Iron
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Below are MeSH descriptors whose meaning is more general than "Iron Chelating Agents".
Below are MeSH descriptors whose meaning is more specific than "Iron Chelating Agents".
This graph shows the total number of publications written about "Iron Chelating Agents" by people in this website by year, and whether "Iron Chelating Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 | 2001 | 1 | 0 | 1 | 2006 | 0 | 1 | 1 | 2007 | 2 | 0 | 2 | 2008 | 2 | 0 | 2 | 2011 | 2 | 0 | 2 | 2013 | 0 | 1 | 1 | 2020 | 0 | 1 | 1 | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Iron Chelating Agents" by people in Profiles.
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Hurtado J, Sellak H, Joseph G, Lewis CV, Naudin CR, Garcia S, Wodicka JR, Archer DR, Taylor WR. Accelerated atherosclerosis in beta-thalassemia. Am J Physiol Heart Circ Physiol. 2023 11 01; 325(5):H1133-H1143.
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Pasupneti S, Tian W, Tu AB, Dahms P, Granucci E, Gandjeva A, Xiang M, Butcher EC, Semenza GL, Tuder RM, Jiang X, Nicolls MR. Endothelial HIF-2a as a Key Endogenous Mediator Preventing Emphysema. Am J Respir Crit Care Med. 2020 10 01; 202(7):983-995.
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Horwitz LD, Horwitz MA. The exochelins of pathogenic mycobacteria: unique, highly potent, lipid- and water-soluble hexadentate iron chelators with multiple potential therapeutic uses. Antioxid Redox Signal. 2014 Dec 01; 21(16):2246-61.
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DeRuisseau KC, Park YM, DeRuisseau LR, Cowley PM, Fazen CH, Doyle RP. Aging-related changes in the iron status of skeletal muscle. Exp Gerontol. 2013 Nov; 48(11):1294-302.
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Danjou F, Origa R, Anni F, Saba L, Cossa S, Podda G, Galanello R. Longitudinal analysis of heart and liver iron in thalassemia major patients according to chelation treatment. Blood Cells Mol Dis. 2013 Oct; 51(3):142-5.
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Allen DL, Abrahamsson S, Murphy MF, Roberts DJ. Human platelet antigen 1a epitopes are dependent on the cation-regulated conformation of integrin a(IIb)?(3) (GPIIb/IIIa). J Immunol Methods. 2012 Jan 31; 375(1-2):166-75.
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Vichinsky E, Bernaudin F, Forni GL, Gardner R, Hassell K, Heeney MM, Inusa B, Kutlar A, Lane P, Mathias L, Porter J, Tebbi C, Wilson F, Griffel L, Deng W, Giannone V, Coates T. Long-term safety and efficacy of deferasirox (Exjade) for up to 5 years in transfusional iron-overloaded patients with sickle cell disease. Br J Haematol. 2011 Aug; 154(3):387-97.
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Baek JH, Reiter CE, Manalo DJ, Buehler PW, Hider RC, Alayash AI. Induction of hypoxia inducible factor (HIF-1a) in rat kidneys by iron chelation with the hydroxypyridinone, CP94. Biochim Biophys Acta. 2011 Apr-Jun; 1809(4-6):262-8.
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Arreguin S, Nelson P, Padway S, Shirazi M, Pierpont C. Dopamine complexes of iron in the etiology and pathogenesis of Parkinson's disease. J Inorg Biochem. 2009 Jan; 103(1):87-93.
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Brosnahan G, Gokden N, Swaminathan S. Acute interstitial nephritis due to deferasirox: a case report. Nephrol Dial Transplant. 2008 Oct; 23(10):3356-8.
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