 Aldehyde Reductase
"Aldehyde Reductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes reversibly the oxidation of an aldose to an alditol. It possesses broad specificity for many aldoses. EC 1.1.1.21.
| Descriptor ID |
D000449
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| MeSH Number(s) |
D08.811.682.047.150.700.156.500 D08.811.682.047.820.284.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aldehyde Reductase".
Below are MeSH descriptors whose meaning is more specific than "Aldehyde Reductase".
This graph shows the total number of publications written about "Aldehyde Reductase" by people in this website by year, and whether "Aldehyde Reductase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 0 | 1 | | 1991 | 2 | 0 | 2 | | 1992 | 4 | 0 | 4 | | 1993 | 3 | 1 | 4 | | 1994 | 1 | 0 | 1 | | 1995 | 1 | 1 | 2 | | 1996 | 3 | 1 | 4 | | 1997 | 4 | 0 | 4 | | 1998 | 2 | 0 | 2 | | 1999 | 3 | 0 | 3 | | 2000 | 2 | 0 | 2 | | 2001 | 4 | 1 | 5 | | 2002 | 3 | 0 | 3 | | 2003 | 0 | 1 | 1 | | 2004 | 3 | 0 | 3 | | 2006 | 1 | 2 | 3 | | 2007 | 2 | 1 | 3 | | 2008 | 3 | 0 | 3 | | 2009 | 2 | 0 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 2 | 0 | 2 | | 2012 | 5 | 1 | 6 | | 2013 | 2 | 5 | 7 | | 2014 | 3 | 2 | 5 | | 2015 | 1 | 0 | 1 | | 2016 | 2 | 2 | 4 | | 2017 | 1 | 1 | 2 | | 2018 | 3 | 0 | 3 | | 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Aldehyde Reductase" by people in Profiles.
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Zukin LM, Pedler MG, Chyung K, Seiwald S, Lenhart P, Shieh B, Petrash JM. Aldose reductase inhibition enhances lens regeneration in mice. Chem Biol Interact. 2019 Jul 01; 307:58-62.
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Sanchez-Lozada LG, Andres-Hernando A, Garcia-Arroyo FE, Cicerchi C, Li N, Kuwabara M, Roncal-Jimenez CA, Johnson RJ, Lanaspa MA. Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats. J Biol Chem. 2019 03 15; 294(11):4272-4281.
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Zukin LM, Pedler MG, Groman-Lupa S, Pantcheva M, Ammar DA, Petrash JM. Aldose Reductase Inhibition Prevents Development of Posterior Capsular Opacification in an In Vivo Model of Cataract Surgery. Invest Ophthalmol Vis Sci. 2018 07 02; 59(8):3591-3598.
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Kalita D, Holm DG, LaBarbera DV, Petrash JM, Jayanty SS. Inhibition of a-glucosidase, a-amylase, and aldose reductase by potato polyphenolic compounds. PLoS One. 2018; 13(1):e0191025.
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Chang KC, Petrash JM. Aldo-Keto Reductases: Multifunctional Proteins as Therapeutic Targets in Diabetes and Inflammatory Disease. Adv Exp Med Biol. 2018; 1032:173-202.
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Andres-Hernando A, Li N, Cicerchi C, Inaba S, Chen W, Roncal-Jimenez C, Le MT, Wempe MF, Milagres T, Ishimoto T, Fini M, Nakagawa T, Johnson RJ, Lanaspa MA. Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice. Nat Commun. 2017 02 13; 8:14181.
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Chang KC, Shieh B, Petrash JM. Influence of aldose reductase on epithelial-to-mesenchymal transition signaling in lens epithelial cells. Chem Biol Interact. 2017 Oct 01; 276:149-154.
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Roncal-Jimenez CA, Milagres T, Andres-Hernando A, Kuwabara M, Jensen T, Song Z, Bjornstad P, Garcia GE, Sato Y, Sanchez-Lozada LG, Lanaspa MA, Johnson RJ. Effects of exogenous desmopressin on a model of heat stress nephropathy in mice. Am J Physiol Renal Physiol. 2017 03 01; 312(3):F418-F426.
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Chang KC, Li L, Sanborn TM, Shieh B, Lenhart P, Ammar D, LaBarbera DV, Petrash JM. Characterization of Emodin as a Therapeutic Agent for Diabetic Cataract. J Nat Prod. 2016 05 27; 79(5):1439-44.
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Chang KC, Shieh B, Petrash JM. Aldose reductase mediates retinal microglia activation. Biochem Biophys Res Commun. 2016 Apr 29; 473(2):565-71.
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