Aldo-Keto Reductase Family 1 Member C3
"Aldo-Keto Reductase Family 1 Member C3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Aldo-keto reductase that functions as a bi-directional 17 BETA, 20 ALPHA-HYDROXYSTEROID DEHYDROGENASE. It catalyzes the reduction of PROSTAGLANDIN D2 and PROSTAGLANDIN H2, as well as the oxidation of 9alpha,11beta-PGF2 to prostaglandin D2. It can also interconvert estrogens, ANDROGENS; and PROGESTINS between their active forms and inactive metabolites.
Descriptor ID |
D000074425
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MeSH Number(s) |
D08.811.682.047.150.700.156.875 D08.811.682.047.436.375.140 D08.811.682.047.820.284.937 D08.811.682.047.820.375.500
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Concept/Terms |
Aldo-Keto Reductase Family 1 Member C3- Aldo-Keto Reductase Family 1 Member C3
- Aldo Keto Reductase Family 1 Member C3
- 17-beta-Hydroxysteroid Dehydrogenase Type 5
- 17 beta Hydroxysteroid Dehydrogenase Type 5
- AKR1C3 Protein
- Dihydrodiol Dehydrogenase 3
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Below are MeSH descriptors whose meaning is more general than "Aldo-Keto Reductase Family 1 Member C3".
Below are MeSH descriptors whose meaning is more specific than "Aldo-Keto Reductase Family 1 Member C3".
This graph shows the total number of publications written about "Aldo-Keto Reductase Family 1 Member C3" by people in this website by year, and whether "Aldo-Keto Reductase Family 1 Member C3" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aldo-Keto Reductase Family 1 Member C3" by people in Profiles.
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Graham LS, True LD, Gulati R, Schade GR, Wright J, Grivas P, Yezefski T, Nega K, Alexander K, Hou WM, Yu EY, Montgomery B, Mostaghel EA, Matsumoto AA, Marck B, Sharifi N, Ellis WJ, Reder NP, Lin DW, Nelson PS, Schweizer MT. Targeting backdoor androgen synthesis through AKR1C3 inhibition: A presurgical hormonal ablative neoadjuvant trial in high-risk localized prostate cancer. Prostate. 2021 05; 81(7):418-426.
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Jia Y, Domenico J, Swasey C, Wang M, Gelfand EW, Lucas JJ. Modulated expression of genes encoding estrogen metabolizing enzymes by G1-phase cyclin-dependent kinases 6 and 4 in human breast cancer cells. PLoS One. 2014; 9(5):e97448.
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