 Cross-Over Studies
"Cross-Over Studies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
| Descriptor ID |
D018592
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| MeSH Number(s) |
E05.318.780.150 N05.715.360.780.150 N06.850.520.445.150
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| Concept/Terms |
Cross-Over Studies- Cross-Over Studies
- Cross Over Studies
- Cross-Over Study
- Studies, Cross-Over
- Study, Cross-Over
- Crossover Studies
- Crossover Study
- Studies, Crossover
- Study, Crossover
- Cross-Over Trials
- Cross Over Trials
- Trial, Cross-Over
- Trials, Cross-Over
- Crossover Trials
- Trial, Crossover
- Trials, Crossover
Cross-Over Design- Cross-Over Design
- Cross Over Design
- Cross-Over Designs
- Design, Cross-Over
- Designs, Cross-Over
- Crossover Design
- Crossover Designs
- Design, Crossover
- Designs, Crossover
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Below are MeSH descriptors whose meaning is more general than "Cross-Over Studies".
Below are MeSH descriptors whose meaning is more specific than "Cross-Over Studies".
This graph shows the total number of publications written about "Cross-Over Studies" by people in this website by year, and whether "Cross-Over Studies" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 5 | 5 | | 1997 | 0 | 5 | 5 | | 1998 | 0 | 3 | 3 | | 1999 | 0 | 4 | 4 | | 2000 | 0 | 5 | 5 | | 2001 | 0 | 4 | 4 | | 2002 | 0 | 6 | 6 | | 2003 | 0 | 6 | 6 | | 2004 | 0 | 11 | 11 | | 2005 | 0 | 11 | 11 | | 2006 | 0 | 12 | 12 | | 2007 | 0 | 7 | 7 | | 2008 | 0 | 12 | 12 | | 2009 | 0 | 10 | 10 | | 2010 | 0 | 10 | 10 | | 2011 | 0 | 15 | 15 | | 2012 | 0 | 16 | 16 | | 2013 | 0 | 20 | 20 | | 2014 | 0 | 22 | 22 | | 2015 | 0 | 18 | 18 | | 2016 | 0 | 20 | 20 | | 2017 | 1 | 22 | 23 | | 2018 | 1 | 17 | 18 | | 2019 | 0 | 22 | 22 | | 2020 | 1 | 16 | 17 | | 2021 | 0 | 21 | 21 | | 2022 | 0 | 16 | 16 | | 2023 | 2 | 11 | 13 | | 2024 | 11 | 8 | 19 | | 2025 | 0 | 26 | 26 | | 2026 | 0 | 4 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Cross-Over Studies" by people in Profiles.
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Moscoso-Vasquez M, Ekhlaspour L, Brown SA, DeBoer MD, Berget C, Cobry EC, Wadwa RP, Capodanno G, Cengiz E, Wong JC, Pryor EC, Villa-Tamayo MF, El Fathi A, Holmes V, Davis Prince S, Escobar E, Towers L, Hosseininpour Y, Narayan A, Koravi CLK, Nguyen T, Fulkerson D, Barnett CL, Oliveri MC, Breton MD, Forlenza GP. Safety and Feasibility of a Fully Automated Insulin Delivery System: FCL@Home, a Multicenter Randomized Clinical Trial in Individuals With Type 1 Diabetes. Diabetes Care. 2026 Mar 01; 49(3):401-409.
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Murray KO, Gioscia-Ryan RA, Justice JN, Santos-Parker JR, Bispham NZ, Hutton DA, Darvish S, Miyamoto-Ditmon J, Clayton ZS, Chonchol M, Seals DR, Rossman MJ. Translational studies of chronic supplementation with a mitochondria-targeted antioxidant to improve physical function with ageing. J Physiol. 2026 04; 604(7):2898-2922.
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Oppenheimer J, Casale TB, Spergel JM, Bernstein DI, Camargo CA, Ellis AK, Fleischer DM, Lowenthal R, Tanimoto S. Pharmacokinetics and Pharmacodynamics Following Repeat Dosing of neffy (Epinephrine Nasal Spray) Versus Intramuscular Injection During Induced Allergic Rhinitis. J Allergy Clin Immunol Pract. 2026 Apr; 14(4):837-845.e3.
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Alabi A, Kerr JS, Shah M, Khan A, Ma JD, Suhandynata RT, Momper JD, Tsunoda SM. Assessment of the Intestinal CYP3A Contribution to Drug Interactions with Extended-Release Tacrolimus (LCPT) Using Grapefruit Juice. Clin Pharmacol Drug Dev. 2026 Jan; 15(1):e70016.
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Cole RM, Colombo E, Angelotti A, Sparagna GC, Choriego RE, Jimenez-Flores R, Ni A, Belury MA. Feasibility Study of Soybean Oil-Fortified Foods to Alter Blood Content of Linoleic Acid and Body Weight: A Randomized Double-Masked Placebo-Controlled Crossover Trial. J Nutr. 2026 Feb; 156(2):101288.
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Zarich S, Cole RM, Fairchild K, Spakowicz D, Sparagna G, Madison A, Ni A, Belury MA. Effects of Walnuts on Postprandial Cognitive Function in Adults With Subjective Cognitive Impairment: Protocol for a Randomized Crossover Trial. JMIR Res Protoc. 2025 Dec 19; 14:e82032.
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Ni W, Benson L, Ljungman P, Nobile F, Breitner S, Zhang S, de Bont J, Lund LH, Savarese G, Schneider A, Agewall S. Short-Term Exposure to Low and High Temperatures and Mortality Among Patients With Heart Failure in Sweden. JAMA Cardiol. 2025 Dec 01; 10(12):1276-1284.
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Gökçe T, Karakus KE, Yesiltepe Mutlu G, Muradoglu S, Eviz E, Can E, Smart C, Hatun S, Gökmen Özel H. Bedtime snacking and glycemic deterioration in young children with Type 1 diabetes on multiple daily injections: a randomized controlled crossover trial. Nutr Diabetes. 2025 Nov 21; 15(1):49.
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Cortes TR, Pescarini JM, Ranzani OT, Paixão ES, Neves DJD, Rebouças P, Ribeiro-Silva RC, Ferreira AJF, Galvão LAC, Brickley EB, Smeeth L, Jacobson LV, Silveira IH, Barreto ML. Ambient temperature and non-accidental mortality: A nationwide space-time-stratified case-crossover study within the 100 million Brazilian Cohort. Environ Int. 2025 Nov; 205:109892.
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Lanskey JH, Jafarian A, Hughes LE, Karadag M, Kocagoncu E, Rouse MA, Adams NE, Naessens M, Raymont V, Woolrich M, Singh KD, Henson RN, Rowe JB. Alzheimer's disease and memantine effects on NMDA-receptor blockade: non-invasive in vivo insights from magnetoencephalography. Mol Psychiatry. 2026 Mar; 31(3):1587-1596.
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