 Quinine
"Quinine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
| Descriptor ID |
D011803
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| MeSH Number(s) |
D03.132.206.719 D03.605.687.762 D03.633.100.810.762
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| Concept/Terms |
Quinine Sulfate- Quinine Sulfate
- Sulfate, Quinine
- Quinine Sulphate
- Sulphate, Quinine
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Below are MeSH descriptors whose meaning is more general than "Quinine".
Below are MeSH descriptors whose meaning is more specific than "Quinine".
This graph shows the total number of publications written about "Quinine" by people in this website by year, and whether "Quinine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 1998 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Quinine" by people in Profiles.
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Vandenbeuch A, Wilson CE, Kinnamon SC. Optogenetic Activation of Type III Taste Cells Modulates Taste Responses. Chem Senses. 2020 10 09; 45(7):533-539.
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Young DS, Miller ES, Bhatia K. Fever and Malaise in an Infant. J Emerg Med. 2017 Aug; 53(2):265-268.
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Hallock RM, Tatangelo M, Barrows J, Finger TE. Residual chemosensory capabilities in double P2X2/P2X3 purinergic receptor null mice: intraoral or postingestive detection? Chem Senses. 2009 Nov; 34(9):799-808.
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Stratford JM, Contreras RJ. Saliva and other taste stimuli are important for gustatory processing of linoleic acid. Am J Physiol Regul Integr Comp Physiol. 2009 Oct; 297(4):R1162-70.
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Bachtell RK, Weitemier AZ, Ryabinin AE. Lesions of the Edinger-Westphal nucleus in C57BL/6J mice disrupt ethanol-induced hypothermia and ethanol consumption. Eur J Neurosci. 2004 Sep; 20(6):1613-23.
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Sano Y, Inamura K, Miyake A, Mochizuki S, Kitada C, Yokoi H, Nozawa K, Okada H, Matsushime H, Furuichi K. A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord. J Biol Chem. 2003 Jul 25; 278(30):27406-12.
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Mundy LS, Janoff EN, Schwebke KE, Shanholtzer CJ, Willard KE. Ambiguity in the identification of Streptococcus pneumoniae. Optochin, bile solubility, quellung, and the AccuProbe DNA probe tests. Am J Clin Pathol. 1998 Jan; 109(1):55-61.
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Mandal AK, Abernathy T, Nelluri SN, Stitzel V. Is quinine effective and safe in leg cramps? J Clin Pharmacol. 1995 Jun; 35(6):588-93.
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Lamb CF, Finger TE. Gustatory control of feeding behavior in goldfish. Physiol Behav. 1995 Mar; 57(3):483-8.
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Parker LA, Maier S, Rennie M, Crebolder J. Morphine- and naltrexone-induced modification of palatability: analysis by the taste reactivity test. Behav Neurosci. 1992 Dec; 106(6):999-1010.
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