Malignant Hyperthermia
"Malignant Hyperthermia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Rapid and excessive rise of temperature accompanied by muscular rigidity following general anesthesia.
Descriptor ID |
D008305
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MeSH Number(s) |
C23.550.505.700 C23.550.767.600
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Concept/Terms |
Malignant Hyperthermia- Malignant Hyperthermia
- Malignant Hyperthermias
- Hyperpyrexia, Malignant
- Hyperpyrexias, Malignant
- Malignant Hyperpyrexias
- Hyperthermia, Malignant
- Malignant Hyperpyrexia
- Anesthesia Related Hyperthermia
- Anesthesia Related Hyperthermias
- Hyperthermia, Anesthesia Related
- Hyperthermias, Anesthesia Related
- Related Hyperthermia, Anesthesia
- Related Hyperthermias, Anesthesia
- Hyperthermia of Anesthesia
- Anesthesia Hyperthermia
- Anesthesia Hyperthermias
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Below are MeSH descriptors whose meaning is more general than "Malignant Hyperthermia".
Below are MeSH descriptors whose meaning is more specific than "Malignant Hyperthermia".
This graph shows the total number of publications written about "Malignant Hyperthermia" by people in this website by year, and whether "Malignant Hyperthermia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 | 2010 | 2 | 0 | 2 | 2012 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Malignant Hyperthermia" by people in Profiles.
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Feng W, Lopez JR, Antrobus S, Zheng J, Uryash A, Dong Y, Beqollari D, Bannister RA, Hopkins PM, Beam KG, Allen PD, Pessah IN. Putative malignant hyperthermia mutation CaV1.1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance. J Biol Chem. 2023 08; 299(8):104992.
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Litman RS, Smith VI, Larach MG, Mayes L, Shukry M, Theroux MC, Watt S, Wong CA. Consensus Statement of the Malignant Hyperthermia Association of the United States on Unresolved Clinical Questions Concerning the Management of Patients With Malignant Hyperthermia. Anesth Analg. 2019 04; 128(4):652-659.
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Larach MG, Klumpner TT, Brandom BW, Vaughn MT, Belani KG, Herlich A, Kim TW, Limoncelli J, Riazi S, Sivak EL, Capacchione J, Mashman D, Kheterpal S, Kooij F, Wilczak J, Soto R, Berris J, Price Z, Lins S, Coles P, Harris JM, Cummings KC, Berman MF, Nanamori M, Adelman BT, Wedeven C, LaGorio J, McCormick PJ, Tom S, Aziz MF, Coffman T, Ellis TA, Molina S, Peterson W, Mackey SC, van Klei WA, Ginde AA, Biggs DA, Neuman MD, Craft RM, Pace NL, Paganelli WC, Durieux ME, Nair BJ, Wanderer JP, Miller SA, Helsten DL, Turnbull ZA, Schonberger RB. Succinylcholine Use and Dantrolene Availability for Malignant Hyperthermia Treatment: Database Analyses and Systematic Review. Anesthesiology. 2019 01; 130(1):41-54.
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Gleich SJ, Strupp K, Wilder RT, Kor DJ, Flick R. An automated real-time method for the detection of patients at risk for malignant hyperthermia. Paediatr Anaesth. 2016 Sep; 26(9):876-82.
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King MR, Firth PG, Yaster M, Ahmed Z, Mai CL. Malignant hyperthermia in the early days of pediatric anesthesia: an interview with anesthesiology pioneer, Dr. John F. Ryan. Paediatr Anaesth. 2015 Sep; 25(9):871-6.
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Bannister RA, Beam KG. Impaired gating of an L-Type Ca(2+) channel carrying a mutation linked to malignant hyperthermia. Biophys J. 2013 May 07; 104(9):1917-22.
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Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, L?pez JR, Beam KG, Allen PD. Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor. Proc Natl Acad Sci U S A. 2012 May 15; 109(20):7923-8.
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Est?ve E, Eltit JM, Bannister RA, Liu K, Pessah IN, Beam KG, Allen PD, L?pez JR. A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR. J Gen Physiol. 2010 Jun; 135(6):619-28.
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Bannister RA, Est?ve E, Eltit JM, Pessah IN, Allen PD, L?pez JR, Beam KG. A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels. J Gen Physiol. 2010 Jun; 135(6):629-40.
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Gallant EM, Balog EM, Beam KG. Slow calcium current is not reduced in malignant hyperthermic porcine myotubes. Muscle Nerve. 1996 Apr; 19(4):450-5.
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