Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution
Menu

Contact Us
If you have any questions or feedback please contact us.

Mark D Zabel

TitleProfessor Adjoint
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-IMM MICRO GENERAL OPER

    Collapse Research 
    Collapse research activities and funding
    R25GM148297     (JOHN, GILBERT H)Mar 1, 2023 - Jan 31, 2028
    NIH
    Multi-Track Post-Baccalaureate Research Education Program (MT PREP)
    Role: Co-Principal Investigator
    T34GM140958     (DEAN, GREGG A)Jun 1, 2022 - May 31, 2027
    NIH
    MARC at Colorado State University
    Role: Co-Principal Investigator
    T32GM144856     (JOHN, GILBERT H)Feb 1, 2022 - Jan 31, 2027
    NIH
    Initiative to Maximize Student Development in Translational Medicine
    Role: Co-Principal Investigator
    R56AI122273     (ZABEL, MARK D)Feb 16, 2016 - Jan 31, 2018
    NIH
    Key Molecular Mechanisms of TSEs
    Role: Principal Investigator
    T35OD015130     (ZABEL, MARK D)Aug 1, 2012 - Aug 31, 2022
    NIH
    Veterinary Scholars Summer Research Program
    Role: Principal Investigator
    R01NS075214     (ZABEL, MARK D)Mar 1, 2012 - Feb 28, 2018
    NIH
    Liposome-siRNA-Peptide Complexes as Therapy to Cure Prion Diseases in Mouse Model
    Role: Principal Investigator
    R01NS056379     (ZABEL, MARK D)Jul 1, 2008 - Jun 30, 2013
    NIH
    Key molecular mechanisms of extraneural pathogenesis and transmission of TSEs
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Sepehri Shamloo A, Chiba T, Tijssen JGP, Althof T, Boveda S, Braunschweig F, de Chillou C, Faxén J, Friede T, Fusini L, Gale CP, Hättasch R, Hohendanner F, Junttila J, Kaas T, Kapacee Z, Kiviniemi A, Kutyifa V, Leclercq C, Lenarczyk R, Leyva F, Maeng M, Marijon E, Merino JL, Mont L, Nielsen JC, Olesen KKW, Pontone G, Pürerfellner H, Schmidt G, Schwartz PJ, Sticherling C, Suleiman M, Tan HL, Tfelt-Hansen J, Thiele H, Tscholl V, Verstraelen T, Wilde A, Wu KC, Zabel M, Hindricks G, Dagres N. Mortality reduction with implanted defibrillator for primary prevention of sudden death after Myocardial Infarction: temporal trends in the PROFID study. Eur Heart J. 2026 Aug 28. PMID: 42663237.
      View in: PubMed
    2. Amarasekera AT, Gunaratne AW, Kovoor JG, Thiagalingam A, Chow C, Zaman S, Sivagangabalan G, Tung MKY, Stiles M, Crozier I, Koh KT, Sticherling C, Reichlin T, Wranicz JK, Avramides D, Tsioufis K, Ritter O, Bode K, Tovia-Brodie O, Chia K, Park RE, Nentwich K, Michowitz Y, Svetlosak M, Hatala R, Zabel M, Nagy VK, Merkely B, Taylor A, Billot L, Kovoor P. Prophylactic implantation of implantable cardioverter-defibrillator for the primary prevention of sudden cardiac death after myocardial infarction: protocol for systematic review and meta-analysis of randomised controlled trials. BMJ Open. 2026 Aug 18; 16(8):e107134. PMID: 42613110.
      View in: PubMed
    3. Wagner K, Fox P, Gordon E, Hahn W, Olsen K, Markham A, Buglewicz D, Selemenakis P, Lessard A, Goldstein D, Threatt A, Davis L, Miller-Dawson J, Stockett H, Sanders H, Rugh K, Turner H, Remias M, Williams M, Chavez J, Galindo G, Cialek C, Koch A, Fout A, Fosdick B, Broeckling B, Zabel MD. A multiplexed, paired-pooled droplet digital PCR assay for detection of SARS-CoV-2 in saliva. Sci Rep. 2023 02 22; 13(1):3075. PMID: 36813822.
      View in: PubMed
    4. Hay AJD, Murphy TJ, Popichak KA, Zabel MD, Moreno JA. Adipose-derived mesenchymal stromal cells decrease prion-induced glial inflammation in vitro. Sci Rep. 2022 12 29; 12(1):22567. PMID: 36581683.
      View in: PubMed
    5. Hnatkova K, Andr?ová I, Novotný T, Britton A, Shipley M, Vandenberk B, Sprenkeler DJ, Junttila J, Reichlin T, Schlögl S, Vos MA, Friede T, Bauer A, Huikuri HV, Willems R, Schmidt G, Franz MR, Sticherling C, Zabel M, Malik M. QRS micro-fragmentation as a mortality predictor. Eur Heart J. 2022 10 21; 43(40):4177-4191. PMID: 35187560.
      View in: PubMed
    6. Pelli A, Junttila MJ, Kenttä TV, Schlögl S, Zabel M, Malik M, Reichlin T, Willems R, Vos MA, Harden M, Friede T, Sticherling C, Huikuri HV. Q waves are the strongest electrocardiographic variable associated with primary prophylactic implantable cardioverter-defibrillator benefit: a prospective multicentre study. Europace. 2022 05 03; 24(5):774-783. PMID: 34849744.
      View in: PubMed
    7. Zabel M, Willems R, Lubinski A, Bauer A, Brugada J, Conen D, Flevari P, Hasenfuß G, Svetlosak M, Huikuri HV, Malik M, Pavlovic N, Schmidt G, Sritharan R, Schlögl S, Szavits-Nossan J, Traykov V, Tuinenburg AE, Willich SN, Harden M, Friede T, Svendsen JH, Sticherling C, Merkely B. Clinical effectiveness of primary prevention implantable cardioverter-defibrillators: results of the EU-CERT-ICD controlled multicentre cohort study. Eur Heart J. 2020 09 21; 41(36):3437-3447. PMID: 32372094.
      View in: PubMed
    8. Pelli A, Kenttä TV, Junttila MJ, Bergau L, Zabel M, Malik M, Reichlin T, Willems R, Vos MA, Harden M, Friede T, Sticherling C, Huikuri HV. Electrocardiogram as a predictor of survival without appropriate shocks in primary prophylactic ICD patients: A retrospective multi-center study. Int J Cardiol. 2020 06 15; 309:78-83. PMID: 32188583.
      View in: PubMed
    9. Junttila MJ, Pelli A, Kenttä TV, Friede T, Willems R, Bergau L, Malik M, Vandenberk B, Vos MA, Schmidt G, Merkely B, Lubinski A, Svetlosak M, Braunschweig F, Harden M, Zabel M, Huikuri HV, Sticherling C. Appropriate Shocks and Mortality in Patients With Versus Without Diabetes With Prophylactic Implantable Cardioverter Defibrillators. Diabetes Care. 2020 01; 43(1):196-200. PMID: 31645407.
      View in: PubMed
    10. Zabel M, Schlögl S, Lubinski A, Svendsen JH, Bauer A, Arbelo E, Brusich S, Conen D, Cygankiewicz I, Dommasch M, Flevari P, Galuszka J, Hansen J, Hasenfuß G, Hatala R, Huikuri HV, Kenttä T, Kucejko T, Haarmann H, Harden M, Iovev S, Kääb S, Kaliska G, Katsimardos A, Kasprzak JD, Qavoq D, Lüthje L, Malik M, Novotný T, Pavlovic N, Perge P, Röver C, Schmidt G, Shalganov T, Sritharan R, Svetlosak M, Sallo Z, Szavits-Nossan J, Traykov V, Vandenberk B, Velchev V, Vos MA, Willich SN, Friede T, Willems R, Merkely B, Sticherling C. Present criteria for prophylactic ICD implantation: Insights from the EU-CERT-ICD (Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope) project. J Electrocardiol. 2019 Nov - Dec; 57S:S34-S39. PMID: 31526572.
      View in: PubMed
    11. Osterholm MT, Anderson CJ, Zabel MD, Scheftel JM, Moore KA, Appleby BS. Chronic Wasting Disease in Cervids: Implications for Prion Transmission to Humans and Other Animal Species. mBio. 2019 07 23; 10(4). PMID: 31337719.
      View in: PubMed
    12. Zabel MD, Mollnow L, Bender H. Lipopeptide Delivery of siRNA to the Central Nervous System. Methods Mol Biol. 2019; 1943:389-403. PMID: 30838631.
      View in: PubMed
    13. Malik M, Buxton AE, Huikuri H, Lombardi F, Schmidt G, Zabel M. Noninvasive electrophysiology in risk assessment and screening. Heart Rhythm. 2018 06; 15(6):803-804. PMID: 29857851.
      View in: PubMed
    14. Malik M, Camm AJ, Huikuri H, Lombardi F, Schmidt G, Schwartz PJ, Zabel M. Electronic gadgets and their health-related claims. Int J Cardiol. 2018 05 01; 258:163-164. PMID: 29544925.
      View in: PubMed
    15. Huikuri HV, Zabel M, Lombardi F, Malik M. Measurement of cardiovascular autonomic function: Where to go from here? Int J Cardiol. 2017 12 15; 249:73-74. PMID: 29121760.
      View in: PubMed
    16. Kane SJ, Swanson E, Gordon EO, Rocha S, Bender HR, Donius LR, Aguzzi A, Hannan JP, Zabel MD. Relative Impact of Complement Receptors CD21/35 (Cr2/1) on Scrapie Pathogenesis in Mice. mSphere. 2017 Nov-Dec; 2(6). PMID: 29202042.
      View in: PubMed
    17. Kane SJ, Farley TK, Gordon EO, Estep J, Bender HR, Moreno JA, Bartz J, Telling GC, Pickering MC, Zabel MD. Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis. J Immunol. 2017 12 01; 199(11):3821-3827. PMID: 29070671.
      View in: PubMed
    18. Hoover CE, Davenport KA, Henderson DM, Zabel MD, Hoover EA. Endogenous Brain Lipids Inhibit Prion Amyloid Formation In Vitro. J Virol. 2017 05 01; 91(9). PMID: 28202758.
      View in: PubMed
    19. Meyerett-Reid C, Wyckoff AC, Spraker T, Pulford B, Bender H, Zabel MD. De Novo Generation of a Unique Cervid Prion Strain Using Protein Misfolding Cyclic Amplification. mSphere. 2017 Jan-Feb; 2(1). PMID: 28144628.
      View in: PubMed
    20. Wyckoff AC, Kane S, Lockwood K, Seligman J, Michel B, Hill D, Ortega A, Mangalea MR, Telling GC, Miller MW, Vercauteren K, Zabel MD. Clay Components in Soil Dictate Environmental Stability and Bioavailability of Cervid Prions in Mice. Front Microbiol. 2016; 7:1885. PMID: 27933048.
      View in: PubMed
    21. Bender HR, Kane S, Zabel MD. Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes. J Vis Exp. 2016 07 23; (113). PMID: 27501362.
      View in: PubMed
    22. Nichols TA, Spraker TR, Gidlewski T, Cummings B, Hill D, Kong Q, Balachandran A, VerCauteren KC, Zabel MD. Dietary magnesium and copper affect survival time and neuroinflammation in chronic wasting disease. Prion. 2016 05 03; 10(3):228-50. PMID: 27216881.
      View in: PubMed
    23. Michel B, Ferguson A, Johnson T, Bender H, Meyerett-Reid C, Wyckoff AC, Pulford B, Telling GC, Zabel MD. Complement protein C3 exacerbates prion disease in a mouse model of chronic wasting disease. Int Immunol. 2013 Dec; 25(12):697-702. PMID: 24038599.
      View in: PubMed
    24. Wyckoff AC, Lockwood KL, Meyerett-Reid C, Michel BA, Bender H, VerCauteren KC, Zabel MD. Estimating prion adsorption capacity of soil by BioAssay of Subtracted Infectivity from Complex Solutions (BASICS). PLoS One. 2013; 8(3):e58630. PMID: 23484043.
      View in: PubMed
    25. Michel B, Ferguson A, Johnson T, Bender H, Meyerett-Reid C, Pulford B, von Teichman A, Seelig D, Weis JH, Telling GC, Aguzzi A, Zabel MD. Genetic depletion of complement receptors CD21/35 prevents terminal prion disease in a mouse model of chronic wasting disease. J Immunol. 2012 Nov 01; 189(9):4520-7. PMID: 23002439.
      View in: PubMed
    26. Michel B, Meyerett-Reid C, Johnson T, Ferguson A, Wyckoff C, Pulford B, Bender H, Avery A, Telling G, Dow S, Zabel MD. Incunabular immunological events in prion trafficking. Sci Rep. 2012; 2:440. PMID: 22679554.
      View in: PubMed
    27. Nichols TA, Spraker TR, Gidlewski T, Powers JG, Telling GC, VerCauteren KC, Zabel MD. Detection of prion protein in the cerebrospinal fluid of elk (Cervus canadensis nelsoni) with chronic wasting disease using protein misfolding cyclic amplification. J Vet Diagn Invest. 2012 Jul; 24(4):746-9. PMID: 22621952.
      View in: PubMed
    28. Pulford B, Spraker TR, Wyckoff AC, Meyerett C, Bender H, Ferguson A, Wyatt B, Lockwood K, Powers J, Telling GC, Wild MA, Zabel MD. Detection of PrPCWD in feces from naturally exposed Rocky Mountain elk (Cervus elaphus nelsoni) using protein misfolding cyclic amplification. J Wildl Dis. 2012 Apr; 48(2):425-34. PMID: 22493117.
      View in: PubMed
    29. Johnson TE, Michel BA, Meyerett C, Duffy A, Avery A, Dow S, Zabel MD. Monitoring immune cells trafficking fluorescent prion rods hours after intraperitoneal infection. J Vis Exp. 2010 Nov 19; (45). PMID: 21113122.
      View in: PubMed
    30. Pulford B, Reim N, Bell A, Veatch J, Forster G, Bender H, Meyerett C, Hafeman S, Michel B, Johnson T, Wyckoff AC, Miele G, Julius C, Kranich J, Schenkel A, Dow S, Zabel MD. Liposome-siRNA-peptide complexes cross the blood-brain barrier and significantly decrease PrP on neuronal cells and PrP in infected cell cultures. PLoS One. 2010 Jun 14; 5(6):e11085. PMID: 20559428.
      View in: PubMed
    31. Haley NJ, Mathiason CK, Zabel MD, Telling GC, Hoover EA. Detection of sub-clinical CWD infection in conventional test-negative deer long after oral exposure to urine and feces from CWD+ deer. PLoS One. 2009 Nov 24; 4(11):e7990. PMID: 19956732.
      View in: PubMed
    32. Mildner A, Mack M, Schmidt H, Brück W, Djukic M, Zabel MD, Hille A, Priller J, Prinz M. CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system. Brain. 2009 Sep; 132(Pt 9):2487-500. PMID: 19531531.
      View in: PubMed
    33. Haley NJ, Seelig DM, Zabel MD, Telling GC, Hoover EA. Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay. PLoS One. 2009; 4(3):e4848. PMID: 19293928.
      View in: PubMed
    Zabel's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (146) concept(s)
    _
    Similar People Expand Description
    See all (60) people
    _
    Same Department Expand Description
    Search Department

    Copyright © 2026 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)