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Kara Mould

TitleAffiliate - NJH
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

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    R01HL168278     (MOULD, KARA J)Jul 15, 2024 - Jun 30, 2029
    NIH
    Reparative functions of human airspace macrophage subsets
    Role: Principal Investigator
    K08HL141648     (MOULD, KARA J)Apr 9, 2018 - Mar 31, 2024
    NIH
    Metabolic Reprogramming of Recruited Alveolar Macrophages by Arginine In Acute Lung Injury
    Role: Principal Investigator
    F32HL131397     (MOULD, KARA J)Jul 1, 2016 - Jun 30, 2017
    NIH
    Metabolic Programming of Alveolar Macrophages During Lung Repair
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Castleman MJ, Santos AL, Lesteberg KE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. Activation and pro-inflammatory cytokine production by unswitched memory B cells during SARS-CoV-2 infection. Front Immunol. 2023; 14:1213344. PMID: 37638016.
      View in: PubMed
    2. Moore PK, Anderson KC, McManus SA, Tu TH, King EM, Mould KJ, Redente EF, Henson PM, Janssen WJ, McCubbrey AL. Single-cell RNA sequencing reveals unique monocyte-derived interstitial macrophage subsets during lipopolysaccharide-induced acute lung inflammation. Am J Physiol Lung Cell Mol Physiol. 2023 04 01; 324(4):L536-L549. PMID: 36852927.
      View in: PubMed
    3. Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. Autoantibodies elicited with SARS-CoV-2 infection are linked to alterations in double negative B cells. Front Immunol. 2022; 13:988125. PMID: 36131937.
      View in: PubMed
    4. Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. SARS-CoV-2 infection relaxes peripheral B cell tolerance. J Exp Med. 2022 06 06; 219(6). PMID: 35420627.
      View in: PubMed
    5. Gibbings SL, Haist KC, Nick H, Frasch SC, Glass TH, Vestal B, Danhorn T, Mould KJ, Henson PM, Bratton DL. Heightened turnover and failed maturation of monocyte-derived macrophages in murine chronic granulomatous disease. Blood. 2022 03 17; 139(11):1707-1721. PMID: 34699591.
      View in: PubMed
    6. McCubbrey AL, McManus SA, McClendon JD, Thomas SM, Chatwin HB, Reisz JA, D'Alessandro A, Mould KJ, Bratton DL, Henson PM, Janssen WJ. Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells. Cell Rep. 2022 01 11; 38(2):110222. PMID: 35021097.
      View in: PubMed
    7. Bouchard BA, Colovos C, Lawson MA, Osborn ZT, Sackheim AM, Mould KJ, Janssen WJ, Cohen MJ, Majumdar D, Freeman K. Increased histone-DNA complexes and endothelial-dependent thrombin generation in severe COVID-19. Vascul Pharmacol. 2022 02; 142:106950. PMID: 34871770.
      View in: PubMed
    8. Liao SY, Atif SM, Mould K, Konigsberg IR, Fu R, Davidson E, Li L, Fontenot AP, Maier LA, Yang IV. Single-cell RNA sequencing identifies macrophage transcriptional heterogeneities in granulomatous diseases. Eur Respir J. 2021 06; 57(6). PMID: 33602861.
      View in: PubMed
    9. Mould KJ, Moore CM, McManus SA, McCubbrey AL, McClendon JD, Griesmer CL, Henson PM, Janssen WJ. Airspace Macrophages and Monocytes Exist in Transcriptionally Distinct Subsets in Healthy Adults. Am J Respir Crit Care Med. 2021 04 15; 203(8):946-956. PMID: 33079572.
      View in: PubMed
    10. Douglas IS, Rosenthal CA, Swanson DD, Hiller T, Oakes J, Bach J, Whelchel C, Pickering J, George T, Kearns M, Hanley M, Mould K, Roark S, Mansoori J, Mehta A, Schmidt EP, Neumeier A. Safety and Outcomes of Prolonged Usual Care Prone Position Mechanical Ventilation to Treat Acute Coronavirus Disease 2019 Hypoxemic Respiratory Failure. Crit Care Med. 2021 03 01; 49(3):490-502. PMID: 33405409.
      View in: PubMed
    11. Mould KJ, Janssen WJ. Signs of self-sustained inflammatory circuits in severe COVID pneumonia. Nature. 2021 02; 590(7847):553-554. PMID: 33558748.
      View in: PubMed
    12. Janssen WJ, Danhorn T, Harris C, Mould KJ, Lee FF, Hedin BR, D'Alessandro A, Leach SM, Alper S. Inflammation-Induced Alternative Pre-mRNA Splicing in Mouse Alveolar Macrophages. G3 (Bethesda). 2020 02 06; 10(2):555-567. PMID: 31810980.
      View in: PubMed
    13. Mould KJ, Jackson ND, Henson PM, Seibold M, Janssen WJ. Single cell RNA sequencing identifies unique inflammatory airspace macrophage subsets. JCI Insight. 2019 03 07; 4(5). PMID: 30721157.
      View in: PubMed
    14. Madenspacher JH, Stapleton RD, Suratt BT, Dixon AE, Lih FB, Lowe JM, Mould KJ, Janssen WJ, Morrell ED, Wurfel MM, Garantziotis S, Tomer KB, Fessler MB. Cholestenoic acid is a prognostic biomarker in acute respiratory distress syndrome. J Allergy Clin Immunol. 2019 01; 143(1):440-442.e8. PMID: 30296525.
      View in: PubMed
    15. Mould KJ, Janssen WJ. Recombinant IFN-? for Postseptic Acute Lung Injury-What's the Mechanism? Am J Respir Cell Mol Biol. 2018 07; 59(1):1-2. PMID: 29957050.
      View in: PubMed
    16. Ni K, Gill A, Tseng V, Mikosz AM, Koike K, Beatman EL, Xu CY, Cao D, Gally F, Mould KJ, Serban KA, Schweitzer KS, March KL, Janssen WJ, Nozik-Grayck E, Garantziotis S, Petrache I. Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury. Respir Res. 2018 05 31; 19(1):107. PMID: 29855321.
      View in: PubMed
    17. McCubbrey AL, Barthel L, Mohning MP, Redente EF, Mould KJ, Thomas SM, Leach SM, Danhorn T, Gibbings SL, Jakubzick CV, Henson PM, Janssen WJ. Deletion of c-FLIP from CD11bhi Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis. Am J Respir Cell Mol Biol. 2018 01; 58(1):66-78. PMID: 28850249.
      View in: PubMed
    18. Mohning MP, Thomas SM, Barthel L, Mould KJ, McCubbrey AL, Frasch SC, Bratton DL, Henson PM, Janssen WJ. Phagocytosis of microparticles by alveolar macrophages during acute lung injury requires MerTK. Am J Physiol Lung Cell Mol Physiol. 2018 01 01; 314(1):L69-L82. PMID: 28935638.
      View in: PubMed
    19. Mould KJ, Barthel L, Mohning MP, Thomas SM, McCubbrey AL, Danhorn T, Leach SM, Fingerlin TE, O'Connor BP, Reisz JA, D'Alessandro A, Bratton DL, Jakubzick CV, Janssen WJ. Cell Origin Dictates Programming of Resident versus Recruited Macrophages during Acute Lung Injury. Am J Respir Cell Mol Biol. 2017 09; 57(3):294-306. PMID: 28421818.
      View in: PubMed
    20. McCubbrey AL, Barthel L, Mould KJ, Mohning MP, Redente EF, Janssen WJ. Selective and inducible targeting of CD11b+ mononuclear phagocytes in the murine lung with hCD68-rtTA transgenic systems. Am J Physiol Lung Cell Mol Physiol. 2016 07 01; 311(1):L87-L100. PMID: 27190063.
      View in: PubMed
    21. Fan X, Staitieh BS, Jensen JS, Mould KJ, Greenberg JA, Joshi PC, Koval M, Guidot DM. Activating the Nrf2-mediated antioxidant response element restores barrier function in the alveolar epithelium of HIV-1 transgenic rats. Am J Physiol Lung Cell Mol Physiol. 2013 Aug 01; 305(3):L267-77. PMID: 23748533.
      View in: PubMed
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