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Jerome Michael Fox

TitleAssociate Professor
InstitutionUniversity of Colorado Boulder
DepartmentChemical & Biological Engin

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Friedman AJ, Padgette HM, Kramer L, Liechty ET, Donovan GW, Fox JM, Shirts MR. Biophysical Rationale for the Selective Inhibition of PTP1B over TCPTP by Nonpolar Terpenoids. J Phys Chem B. 2023 10 05; 127(39):8305-8316. PMID: 37729547.
      View in: PubMed
    2. Liechty ET, Hren A, Kramer L, Donovan G, Friedman AJ, Shirts MR, Fox JM. Analysis of neutral mutational drift in an allosteric enzyme. Protein Sci. 2023 08; 32(8):e4719. PMID: 37402140.
      View in: PubMed
    3. Friedman AJ, Padgette HM, Kramer L, Liechty ET, Donovan GW, Fox JM, Shirts MR. A biophysical rationale for the selective inhibition of PTP1B over TCPTP by nonpolar terpenoids. bioRxiv. 2023 Apr 18. PMID: 37131728.
      View in: PubMed
    4. Mains K, Fox JM. Ketosynthase mutants enable short-chain fatty acid biosynthesis in E. coli. Metab Eng. 2023 05; 77:118-127. PMID: 36963462.
      View in: PubMed
    5. Kramer L, Sarkar A, Foderaro T, Markley AL, Lee J, Edstrom H, Sharma S, Gill E, Traylor MJ, Fox JM. Genetically Encoded Detection of Biosynthetic Protease Inhibitors. ACS Synth Biol. 2023 01 20; 12(1):83-94. PMID: 36574400.
      View in: PubMed
    6. Friedman AJ, Liechty ET, Kramer L, Sarkar A, Fox JM, Shirts MR. Allosteric Inhibition of PTP1B by a Nonpolar Terpenoid. J Phys Chem B. 2022 10 27; 126(42):8427-8438. PMID: 36223525.
      View in: PubMed
    7. Peoples J, Ruppe S, Mains K, Cipriano EC, Fox JM. A kinetic framework for modeling oleochemical biosynthesis in Escherichia?coli. Biotechnol Bioeng. 2022 11; 119(11):3149-3161. PMID: 35959746.
      View in: PubMed
    8. Sarkar A, Foderaro T, Kramer L, Markley AL, Lee J, Traylor MJ, Fox JM. Evolution-Guided Biosynthesis of Terpenoid Inhibitors. ACS Synth Biol. 2022 09 16; 11(9):3015-3027. PMID: 35984356.
      View in: PubMed
    9. Hongdusit A, Liechty ET, Fox JM. Analysis of Three Architectures for Controlling PTP1B with Light. ACS Synth Biol. 2022 01 21; 11(1):61-68. PMID: 34898189.
      View in: PubMed
    10. Mains K, Peoples J, Fox JM. Kinetically guided, ratiometric tuning of fatty acid biosynthesis. Metab Eng. 2022 01; 69:209-220. PMID: 34826644.
      View in: PubMed
    11. Sarkar A, Kim EY, Jang T, Hongdusit A, Kim H, Choi JM, Fox JM. Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products. ACS Synth Biol. 2021 06 18; 10(6):1505-1519. PMID: 33988973.
      View in: PubMed
    12. Hongdusit A, Fox JM. Optogenetic Analysis of Allosteric Control in Protein Tyrosine Phosphatases. Biochemistry. 2021 02 02; 60(4):254-258. PMID: 33450156.
      View in: PubMed
    13. Hongdusit A, Liechty ET, Fox JM. Optogenetic interrogation and control of cell signaling. Curr Opin Biotechnol. 2020 12; 66:195-206. PMID: 33053496.
      View in: PubMed
    14. Ruppe S, Mains K, Fox JM. A kinetic rationale for functional redundancy in fatty acid biosynthesis. Proc Natl Acad Sci U S A. 2020 09 22; 117(38):23557-23564. PMID: 32883882.
      View in: PubMed
    15. Hongdusit A, Zwart PH, Sankaran B, Fox JM. Minimally disruptive optical control of protein tyrosine phosphatase 1B. Nat Commun. 2020 02 07; 11(1):788. PMID: 32034150.
      View in: PubMed
    16. Hjortness MK, Riccardi L, Hongdusit A, Ruppe S, Zhao M, Kim EY, Zwart PH, Sankaran B, Arthanari H, Sousa MC, De Vivo M, Fox JM. Correction to "Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation". Biochemistry. 2019 06 18; 58(24):2797. PMID: 31181901.
      View in: PubMed
    17. Ruppe A, Fox JM. Analysis of Interdependent Kinetic Controls of Fatty Acid Synthases. ACS Catal. 2018 Dec 07; 8(12):11722-11734. PMID: 30881730.
      View in: PubMed
    18. Hjortness MK, Riccardi L, Hongdusit A, Zwart PH, Sankaran B, De Vivo M, Fox JM. Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases. Biochemistry. 2018 11 13; 57(45):6443-6451. PMID: 30289703.
      View in: PubMed
    19. Hjortness MK, Riccardi L, Hongdusit A, Ruppe S, Zhao M, Kim EY, Zwart PH, Sankaran B, Arthanari H, Sousa MC, De Vivo M, Fox JM. Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation. Biochemistry. 2018 10 09; 57(40):5886-5896. PMID: 30169954.
      View in: PubMed
    20. Fox JM, Zhao M, Fink MJ, Kang K, Whitesides GM. The Molecular Origin of Enthalpy/Entropy Compensation in Biomolecular Recognition. Annu Rev Biophys. 2018 05 20; 47:223-250. PMID: 29505727.
      View in: PubMed
    21. Fox JM, Kang K, Sastry M, Sherman W, Sankaran B, Zwart PH, Whitesides GM. Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase. Angew Chem Int Ed Engl. 2017 03 27; 56(14):3833-3837. PMID: 28252841.
      View in: PubMed
    22. Semenov SN, Kraft LJ, Ainla A, Zhao M, Baghbanzadeh M, Campbell VE, Kang K, Fox JM, Whitesides GM. Autocatalytic, bistable, oscillatory networks of biologically relevant organic reactions. Nature. 2016 09 29; 537(7622):656-60. PMID: 27680939.
      View in: PubMed
    23. Kang K, Choi JM, Fox JM, Snyder PW, Moustakas DT, Whitesides GM. Acetylation of Surface Lysine Groups of a Protein Alters the Organization and Composition of Its Crystal Contacts. J Phys Chem B. 2016 07 14; 120(27):6461-8. PMID: 27292012.
      View in: PubMed
    24. Fox JM, Whitesides GM. Reply to Sullivan and Cruz: Defense of a simplified physical model. Proc Natl Acad Sci U S A. 2015 Aug 04; 112(31):E4165. PMID: 26183230.
      View in: PubMed
    25. Fox JM, Kang K, Sherman W, H?roux A, Sastry GM, Baghbanzadeh M, Lockett MR, Whitesides GM. Interactions between Hofmeister anions and the binding pocket of a protein. J Am Chem Soc. 2015 Mar 25; 137(11):3859-66. PMID: 25738615.
      View in: PubMed
    26. Fox JM, Whitesides GM. Warning signals for eruptive events in spreading fires. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2378-83. PMID: 25675491.
      View in: PubMed
    27. Nemiroski A, Gonidec M, Fox JM, Jean-Remy P, Turnage E, Whitesides GM. Engineering shadows to fabricate optical metasurfaces. ACS Nano. 2014 Nov 25; 8(11):11061-70. PMID: 25209062.
      View in: PubMed
    28. Fox JM, Jess P, Jambusaria RB, Moo GM, Liphardt J, Clark DS, Blanch HW. A single-molecule analysis reveals morphological targets for cellulase synergy. Nat Chem Biol. 2013 Jun; 9(6):356-61. PMID: 23563526.
      View in: PubMed
    29. Fox JM, Levine SE, Blanch HW, Clark DS. An evaluation of cellulose saccharification and fermentation with an engineered Saccharomyces cerevisiae capable of cellobiose and xylose utilization. Biotechnol J. 2012 Mar; 7(3):361-73. PMID: 22228702.
      View in: PubMed
    30. Fox JM, Levine SE, Clark DS, Blanch HW. Initial- and processive-cut products reveal cellobiohydrolase rate limitations and the role of companion enzymes. Biochemistry. 2012 Jan 10; 51(1):442-52. PMID: 22103405.
      View in: PubMed
    31. Levine SE, Fox JM, Clark DS, Blanch HW. A mechanistic model for rational design of optimal cellulase mixtures. Biotechnol Bioeng. 2011 Nov; 108(11):2561-70. PMID: 21702033.
      View in: PubMed
    32. Levine SE, Fox JM, Blanch HW, Clark DS. A mechanistic model of the enzymatic hydrolysis of cellulose. Biotechnol Bioeng. 2010 Sep 01; 107(1):37-51. PMID: 20506540.
      View in: PubMed
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