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Kimberley Bruce

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cleland NRW, Potter GJ, Buck C, Quang D, Oldham D, Neal M, Saviola A, Niemeyer CS, Dobrinskikh E, Bruce KD. Altered metabolism and DAM-signatures in female brains and microglia with aging. Brain Res. 2024 Apr 15; 1829:148772. PMID: 38244754.
      View in: PubMed
    2. Cleland NRW, Potter GJ, Buck C, Quang D, Oldham D, Neal M, Saviola A, Niemeyer CS, Dobrinskikh E, Bruce KD. Altered Metabolism and DAM-signatures in Female Brains and Microglia with Aging. bioRxiv. 2023 Nov 30. PMID: 38076915.
      View in: PubMed
    3. Bruce KD, Eckel RH. Can DNA Methylation Predict the Lipid Response to Dietary Intervention? There's a Fat Chance. J Clin Endocrinol Metab. 2023 Nov 17; 108(12):e1747-e1748. PMID: 37191137.
      View in: PubMed
    4. Tobeh NS, Bruce KD. Emerging Alzheimer's disease therapeutics: promising insights from lipid metabolism and microglia-focused interventions. Front Aging Neurosci. 2023; 15:1259012. PMID: 38020773.
      View in: PubMed
    5. Lightbourne M, Startzell M, Bruce KD, Brite B, Muniyappa R, Skarulis M, Shamburek R, Gharib AM, Ouwerkerk R, Walter M, Eckel RH, Brown RJ. Volanesorsen, an antisense oligonucleotide to apolipoprotein C-III, increases lipoprotein lipase activity and lowers triglycerides in partial lipodystrophy. J Clin Lipidol. 2022 Nov-Dec; 16(6):850-862. PMID: 36195542.
      View in: PubMed
    6. Cleland NRW, Bruce KD. Fatty acid sensing in the brain: The role of glial-neuronal metabolic crosstalk and horizontal lipid flux. Biochimie. 2024 Aug; 223:166-178. PMID: 35998849.
      View in: PubMed
    7. Oldham D, Wang H, Mullen J, Lietzke E, Sprenger K, Reigan P, Eckel RH, Bruce KD. Using Synthetic ApoC-II Peptides and nAngptl4 Fragments to Measure Lipoprotein Lipase Activity in Radiometric and Fluorescent Assays. Front Cardiovasc Med. 2022; 9:926631. PMID: 35911520.
      View in: PubMed
    8. Eckel RH, Bruce KD. Statins, gut microbiome, LDL-C, glucose intolerance: Personalized medicine timely? Med. 2022 06 10; 3(6):355-357. PMID: 35690054.
      View in: PubMed
    9. Cleland NRW, Al-Juboori SI, Dobrinskikh E, Bruce KD. Altered substrate metabolism in neurodegenerative disease: new insights from metabolic imaging. J Neuroinflammation. 2021 Oct 28; 18(1):248. PMID: 34711251.
      View in: PubMed
    10. Bruce KD, Yassine HN, Fonteh AN. Editorial: Lipid Metabolism and Transport in CNS Health and Disease. Front Physiol. 2021; 12:768417. PMID: 34721089.
      View in: PubMed
    11. Loving BA, Tang M, Neal MC, Gorkhali S, Murphy R, Eckel RH, Bruce KD. Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation. Cells. 2021 01 20; 10(2). PMID: 33498265.
      View in: PubMed
    12. Joshi M, Kim J, D'Alessandro A, Monk E, Bruce K, Elajaili H, Nozik-Grayck E, Goodspeed A, Costello JC, Schlaepfer IR. CPT1A Over-Expression Increases Reactive Oxygen Species in the Mitochondria and Promotes Antioxidant Defenses in Prostate Cancer. Cancers (Basel). 2020 Nov 18; 12(11). PMID: 33218188.
      View in: PubMed
    13. Bruce KD, Dobrinskikh E, Wang H, Rudenko I, Gao H, Libby AE, Gorkhali S, Yu T, Zsombok A, Eckel RH. Neuronal Lipoprotein Lipase Deficiency Alters Neuronal Function and Hepatic Metabolism. Metabolites. 2020 Sep 28; 10(10). PMID: 32998280.
      View in: PubMed
    14. Coughlan C, Bruce KD, Burgy O, Boyd TD, Michel CR, Garcia-Perez JE, Adame V, Anton P, Bettcher BM, Chial HJ, K?nigshoff M, Hsieh EWY, Graner M, Potter H. Exosome Isolation by Ultracentrifugation and Precipitation and Techniques for Downstream Analyses. Curr Protoc Cell Biol. 2020 09; 88(1):e110. PMID: 32633898.
      View in: PubMed
    15. Loving BA, Bruce KD. Lipid and Lipoprotein Metabolism in Microglia. Front Physiol. 2020; 11:393. PMID: 32411016.
      View in: PubMed
    16. Amison RT, Faure ME, O'Shaughnessy BG, Bruce KD, Hu Y, Coates A, Page CP. The small quinolone derived compound HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo. Pulm Pharmacol Ther. 2020 04; 61:101884. PMID: 31887372.
      View in: PubMed
    17. Cleal JK, Bruce KD, Shearer JL, Thomas H, Plume J, Gregory L, Shepard JN, Spiers-Fitzgerald KL, Mani R, Lewis RM, Lillycrop KA, Hanson MA, Byrne CD, Cagampang FR. Maternal Obesity during Pregnancy Alters Daily Activity and Feeding Cycles, and Hypothalamic Clock Gene Expression in Adult Male Mouse Offspring. Int J Mol Sci. 2019 Oct 30; 20(21). PMID: 31671625.
      View in: PubMed
    18. Jonscher KR, Bruce KD. Current Models of Fatty Liver Disease; New Insights, Therapeutic Targets and Interventions. Adv Exp Med Biol. 2019; 1134:33-58. PMID: 30919331.
      View in: PubMed
    19. Bruce KD, Gorkhali S, Given K, Coates AM, Boyle KE, Macklin WB, Eckel RH. Lipoprotein Lipase Is a Feature of Alternatively-Activated Microglia and May Facilitate Lipid Uptake in the CNS During Demyelination. Front Mol Neurosci. 2018; 11:57. PMID: 29599706.
      View in: PubMed
    20. Bruce KD, Jonscher KR. Assessment of Fatty Liver in Models of Disease Programming. Methods Mol Biol. 2018; 1735:251-266. PMID: 29380318.
      View in: PubMed
    21. Laperrousaz E, Moull? VS, Denis RG, Kassis N, Berland C, Colsch B, Fioramonti X, Philippe E, Lacombe A, Vanacker C, Butin N, Bruce KD, Wang H, Wang Y, Gao Y, Garcia-Caceres C, Pr?vot V, Tsch?p MH, Eckel RH, Le Stunff H, Luquet S, Magnan C, Cruciani-Guglielmacci C. Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice. Diabetologia. 2017 07; 60(7):1314-1324. PMID: 28456865.
      View in: PubMed
    22. Bruce KD, Zsombok A, Eckel RH. Lipid Processing in the Brain: A Key Regulator of Systemic Metabolism. Front Endocrinol (Lausanne). 2017; 8:60. PMID: 28421037.
      View in: PubMed
    23. Taha DA, Zgair A, Lee JB, de Moor CH, Barrett DA, Bruce KD, Sungelo M, Eckel RH, Gershkovich P. Hyperlipidaemia alone and in combination with acidosis can increase the incidence and severity of statin-induced myotoxicity. Eur J Pharm Sci. 2017 Mar 30; 100:163-175. PMID: 28104473.
      View in: PubMed
    24. Bruce KD, Szczepankiewicz D, Sihota KK, Ravindraanandan M, Thomas H, Lillycrop KA, Burdge GC, Hanson MA, Byrne CD, Cagampang FR. Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH. Biochim Biophys Acta. 2016 Jul; 1861(7):584-93. PMID: 27040510.
      View in: PubMed
    25. Wang H, Taussig MD, DiPatrizio NV, Bruce K, Piomelli D, Eckel RH. Obesity development in neuron-specific lipoprotein lipase deficient mice is not responsive to increased dietary fat content or change in fat composition. Metabolism. 2016 07; 65(7):987-97. PMID: 27282869.
      View in: PubMed
    26. Cheong Y, Sadek KH, Bruce KD, Macklon N, Cagampang FR. Diet-induced maternal obesity alters ovarian morphology and gene expression in the adult mouse offspring. Fertil Steril. 2014 Sep; 102(3):899-907. PMID: 25063726.
      View in: PubMed
    27. Cleal JK, Shepherd JN, Shearer JL, Bruce KD, Cagampang FR. Sensitivity of housekeeping genes in the suprachiasmatic nucleus of the mouse brain to diet and the daily light-dark cycle. Brain Res. 2014 Aug 05; 1575:72-7. PMID: 24881883.
      View in: PubMed
    28. Torrens C, Ethirajan P, Bruce KD, Cagampang FR, Siow RC, Hanson MA, Byrne CD, Mann GE, Clough GF. Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice. PLoS One. 2012; 7(12):e50671. PMID: 23227196.
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    29. Sadek KH, Cagampang FR, Bruce KD, Macklon N, Cheong Y. Variation in stability of housekeeping genes in healthy and adhesion-related mesothelium. Fertil Steril. 2012 Oct; 98(4):1023-7. PMID: 22795637.
      View in: PubMed
    30. Cagampang FR, Bruce KD. The role of the circadian clock system in nutrition and metabolism. Br J Nutr. 2012 Aug; 108(3):381-92. PMID: 22676899.
      View in: PubMed
    31. Bruce KD, Sihota KK, Byrne CD, Cagampang FR. The housekeeping gene YWHAZ remains stable in a model of developmentally primed non-alcoholic fatty liver disease. Liver Int. 2012 Sep; 32(8):1315-21. PMID: 22583519.
      View in: PubMed
    32. Sadek KH, Cagampang FR, Bruce KD, Shreeve N, Macklon N, Cheong Y. Variation in stability of housekeeping genes in endometrium of healthy and polycystic ovarian syndrome women. Hum Reprod. 2012 Jan; 27(1):251-6. PMID: 22052386.
      View in: PubMed
    33. Bruce KD, Cagampang FR. Epigenetic priming of the metabolic syndrome. Toxicol Mech Methods. 2011 May; 21(4):353-61. PMID: 21495873.
      View in: PubMed
    34. Sadek K, Macklon N, Bruce K, Cagampang F, Cheong Y. Hypothesis: Role for the circadian Clock system and sleep in the pathogenesis of adhesions and chronic pelvic pain? Med Hypotheses. 2011 Mar; 76(3):453-6. PMID: 21146320.
      View in: PubMed
    35. Bruce KD, Hanson MA. The developmental origins, mechanisms, and implications of metabolic syndrome. J Nutr. 2010 Mar; 140(3):648-52. PMID: 20107145.
      View in: PubMed
    36. Bruce KD, Cagampang FR, Argenton M, Zhang J, Ethirajan PL, Burdge GC, Bateman AC, Clough GF, Poston L, Hanson MA, McConnell JM, Byrne CD. Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression. Hepatology. 2009 Dec; 50(6):1796-808. PMID: 19816994.
      View in: PubMed
    37. Bruce KD, Byrne CD. The metabolic syndrome: common origins of a multifactorial disorder. Postgrad Med J. 2009 Nov; 85(1009):614-21. PMID: 19892897.
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    38. Zhang J, Zhang F, Didelot X, Bruce KD, Cagampang FR, Vatish M, Hanson M, Lehnert H, Ceriello A, Byrne CD. Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring. BMC Genomics. 2009 Oct 16; 10:478. PMID: 19835573.
      View in: PubMed
    39. Byrne CD, Olufadi R, Bruce KD, Cagampang FR, Ahmed MH. Metabolic disturbances in non-alcoholic fatty liver disease. Clin Sci (Lond). 2009 Apr; 116(7):539-64. PMID: 19243311.
      View in: PubMed
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