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Fredrick Rosario-Joseph

InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-OB/GYN BRS

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Rosario FJ, Gupta MB, Myatt L, Powell TL, Glenn JP, Cox L, Jansson T. Mechanistic Target of Rapamycin Complex 1 Promotes the Expression of Genes Encoding Electron Transport Chain Proteins and Stimulates Oxidative Phosphorylation in Primary Human Trophoblast Cells by Regulating Mitochondrial Biogenesis. Sci Rep. 2019 Jan 22; 9(1):246. PMID: 30670706.
      View in: PubMed
    2. Paulsen ME, Rosario FJ, Wesolowski SR, Powell TL, Jansson T. Normalizing adiponectin levels in obese pregnant mice prevents adverse metabolic outcomes in offspring. FASEB J. 2019 Feb; 33(2):2899-2909. PMID: 30346829.
      View in: PubMed
    3. Lager S, Ramirez VI, Acosta O, Meireles C, Miller E, Gaccioli F, Rosario FJ, Gelfond JAL, Hakala K, Weintraub ST, Krummel DA, Powell TL. Docosahexaenoic Acid Supplementation in Pregnancy Modulates Placental Cellular Signaling and Nutrient Transport Capacity in Obese Women. J Clin Endocrinol Metab. 2017 12 01; 102(12):4557-4567. PMID: 29053802.
      View in: PubMed
    4. Dimasuay KG, Gong L, Rosario F, McBryde E, Spelman T, Glazier J, Rogerson SJ, Beeson JG, Jansson T, Devenish RJ, Boeuf P. Impaired placental autophagy in placental malaria. PLoS One. 2017; 12(11):e0187291. PMID: 29125872.
      View in: PubMed
    5. Rosario FJ, Nathanielsz PW, Powell TL, Jansson T. Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice. Sci Rep. 2017 06 21; 7(1):3982. PMID: 28638048.
      View in: PubMed
    6. Silva E, Rosario FJ, Powell TL, Jansson T. Mechanistic Target of Rapamycin Is a Novel Molecular Mechanism Linking Folate Availability and Cell Function. J Nutr. 2017 07; 147(7):1237-1242. PMID: 28592519.
      View in: PubMed
    7. Rosario FJ, Powell TL, Jansson T. mTOR folate sensing links folate availability to trophoblast cell function. J Physiol. 2017 07 01; 595(13):4189-4206. PMID: 28374905.
      View in: PubMed
    8. Vaughan OR, Rosario FJ, Powell TL, Jansson T. Regulation of Placental Amino Acid Transport and Fetal Growth. Prog Mol Biol Transl Sci. 2017; 145:217-251. PMID: 28110752.
      View in: PubMed
    9. Dimasuay KG, Aitken EH, Rosario F, Njie M, Glazier J, Rogerson SJ, Fowkes FJ, Beeson JG, Powell T, Jansson T, Boeuf P. Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight. BMC Med. 2017 Jan 03; 15(1):1. PMID: 28049467.
      View in: PubMed
    10. Pantham P, Rosario FJ, Weintraub ST, Nathanielsz PW, Powell TL, Li C, Jansson T. Down-Regulation of Placental Transport of Amino Acids Precedes the Development of Intrauterine Growth Restriction in Maternal Nutrient Restricted Baboons. Biol Reprod. 2016 11; 95(5):98. PMID: 27605346.
      View in: PubMed
    11. Rosario FJ, Powell TL, Jansson T. Mechanistic target of rapamycin (mTOR) regulates trophoblast folate uptake by modulating the cell surface expression of FR-a and the RFC. Sci Rep. 2016 08 26; 6:31705. PMID: 27562465.
      View in: PubMed
    12. Aye IL, Rosario FJ, Powell TL, Jansson T. Reply to Carbillon: Fetal/placental weight ratio and placental function. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):E261. PMID: 26755612; PMCID: PMC4725469.
    13. Rosario FJ, Dimasuay KG, Kanai Y, Powell TL, Jansson T. Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2. Clin Sci (Lond). 2016 Apr 01; 130(7):499-512. PMID: 26608079.
      View in: PubMed
    14. Rosario FJ, Powell TL, Jansson T. Activation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth. Am J Physiol Regul Integr Comp Physiol. 2016 Jan 01; 310(1):R87-93. PMID: 26491103; PMCID: PMC4796632 [Available on 01/01/17].
    15. Díaz P, Harris J, Rosario FJ, Powell TL, Jansson T. Increased placental fatty acid transporter 6 and binding protein 3 expression and fetal liver lipid accumulation in a mouse model of obesity in pregnancy. Am J Physiol Regul Integr Comp Physiol. 2015 Dec 15; 309(12):R1569-77. PMID: 26491104; PMCID: PMC4698418 [Available on 12/15/16].
    16. Aye IL, Rosario FJ, Powell TL, Jansson T. Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth. Proc Natl Acad Sci U S A. 2015 Oct 13; 112(41):12858-63. PMID: 26417088; PMCID: PMC4611638.
    17. Chen YY, Rosario FJ, Shehab MA, Powell TL, Gupta MB, Jansson T. Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR. Clin Sci (Lond). 2015 Dec; 129(12):1131-41. PMID: 26374858; PMCID: PMC4614027.
    18. Pantham P, Rosario FJ, Nijland M, Cheung A, Nathanielsz PW, Powell TL, Galan HL, Li C, Jansson T. Reduced placental amino acid transport in response to maternal nutrient restriction in the baboon. Am J Physiol Regul Integr Comp Physiol. 2015 Oct; 309(7):R740-6. PMID: 26246504; PMCID: PMC4666932 [Available on 10/01/16].
    19. Rosario FJ, Kanai Y, Powell TL, Jansson T. Increased placental nutrient transport in a novel mouse model of maternal obesity with fetal overgrowth. Obesity (Silver Spring). 2015 Aug; 23(8):1663-70. PMID: 26193061; PMCID: PMC4509489.
    20. Abu Shehab M, Damerill I, Shen T, Rosario FJ, Nijland M, Nathanielsz PW, Kamat A, Jansson T, Gupta MB. Liver mTOR controls IGF-I bioavailability by regulation of protein kinase CK2 and IGFBP-1 phosphorylation in fetal growth restriction. Endocrinology. 2014 Apr; 155(4):1327-39. PMID: 24437487; PMCID: PMC3959599.
    21. Kavitha JV, Rosario FJ, Nijland MJ, McDonald TJ, Wu G, Kanai Y, Powell TL, Nathanielsz PW, Jansson T. Down-regulation of placental mTOR, insulin/IGF-I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon. FASEB J. 2014 Mar; 28(3):1294-305. PMID: 24334703; PMCID: PMC3929672.
    22. Rosario FJ, Kanai Y, Powell TL, Jansson T. Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells. J Physiol. 2013 Feb 01; 591(3):609-25. PMID: 23165769; PMCID: PMC3577540.
    23. Jansson N, Rosario FJ, Gaccioli F, Lager S, Jones HN, Roos S, Jansson T, Powell TL. Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies. J Clin Endocrinol Metab. 2013 Jan; 98(1):105-13. PMID: 23150676; PMCID: PMC3537112.
    24. Rosario FJ, Sadovsky Y, Jansson T. Gene targeting in primary human trophoblasts. Placenta. 2012 Oct; 33(10):754-62. PMID: 22831880; PMCID: PMC3439563.
    25. Rosario FJ, Schumacher MA, Jiang J, Kanai Y, Powell TL, Jansson T. Chronic maternal infusion of full-length adiponectin in pregnant mice down-regulates placental amino acid transporter activity and expression and decreases fetal growth. J Physiol. 2012 Mar 15; 590(6):1495-509. PMID: 22289908; PMCID: PMC3382336.
    26. Rosario FJ, Jansson N, Kanai Y, Prasad PD, Powell TL, Jansson T. Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters. Endocrinology. 2011 Mar; 152(3):1119-29. PMID: 21285325; PMCID: PMC3858644.
    27. Rosario JF, Gomez MP, Anbu P. Does the maternal micronutrient deficiency (copper or zinc or vitamin E) modulate the expression of placental 11 beta hydroxysteroid dehydrogenase-2 per se predispose offspring to insulin resistance and hypertension in later life? Indian J Physiol Pharmacol. 2008 Oct-Dec; 52(4):355-65. PMID: 19585752.
      View in: PubMed
    28. Kavitha JV, Rosario JF, Chandran J, Anbu P. Hypoglycemic and other related effects of Boswellia glabra in alloxan-induced diabetic rats. Indian J Physiol Pharmacol. 2007 Jan-Mar; 51(1):29-39. PMID: 17877290.
      View in: PubMed
    29. Ghosh D, Dhawan L, Lalitkumar PG, Wong V, Rosario JF, Hendrickx AG, Lasley BL, Overstreet JW, Sengupta J. Effect of vaginally administered (Ala(8,13,18))-magainin II amide on the morphology of implantation stage endometrium in the rhesus monkey (Macaca mulatta). Contraception. 2001 Jun; 63(6):335-42. PMID: 11672557.
      View in: PubMed
    30. Ghosh D, Lalitkumar PG, Wong V, Dhawan L, Rosario JF, Hendrickx AG, Lasley BL, Overstreet JW, Sengupta J. Effect of vaginally administered fumagillin on the morphology of implantation stage endometrium in the rhesus monkey. Contraception. 2001 Feb; 63(2):95-102. PMID: 11292474.
      View in: PubMed
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