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Search Results to Lynn E Heasley

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One or more keywords matched the following items that are connected to Heasley, Lynn

Item TypeName
Academic Article Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation.
Academic Article Tyrosine kinase growth factor receptors but not seven-membrane-spanning receptors or phorbol esters activate mitogen-activated protein kinase in rat hepatocytes.
Academic Article Activation of Jun kinase/stress-activated protein kinase by GTPase-deficient mutants of G alpha 12 and G alpha 13.
Academic Article Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C.
Academic Article Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells.
Academic Article Multiple mitogen-activated protein kinases are regulated by hyperosmolality in mouse IMCD cells.
Academic Article c-Jun NH2-terminal kinase regulation of the apoptotic response of small cell lung cancer cells to ultraviolet radiation.
Academic Article Dominant-negative c-Jun NH2-terminal kinase 2 sensitizes renal inner medullary collecting duct cells to hypertonicity-induced lethality independent of organic osmolyte transport.
Academic Article Expression of catalytically inactive phospholipase Cbeta disrupts phospholipase Cbeta and mitogen-activated protein kinase signaling and inhibits small cell lung cancer growth.
Academic Article New therapeutic strategies for lung cancer: biology and molecular biology come of age.
Academic Article Inhibitory actions of cyclic adenosine monophosphate and pertussis toxin define two distinct epidermal growth factor-regulated pathways leading to activation of mitogen-activated protein kinase in rat hepatocytes.
Academic Article Isoforms of Jun kinase are differentially expressed and activated in human monocyte/macrophage (THP-1) cells.
Academic Article In vivo regulation of MAP kinases in Ratus norvegicus renal papilla by water loading and restriction.
Academic Article Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model.
Academic Article Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression.
Academic Article TRH regulates Kv1.5 gene expression through a Galphaq-mediated PLC-independent pathway.
Academic Article Protein kinase C d is a downstream effector of oncogenic K-ras in lung tumors.
Academic Article Prolactin stimulates activation of c-jun N-terminal kinase (JNK).
Academic Article Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer.
Academic Article Regulation of protein kinase C by nerve growth factor, epidermal growth factor, and phorbol esters in PC12 pheochromocytoma cells.
Academic Article Differential modulation of bombesin-stimulated phospholipase C beta and mitogen-activated protein kinase activity by [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P.
Academic Article Expression of a mutant Gi2 alpha subunit inhibits ATP and thrombin stimulation of cytoplasmic phospholipase A2-mediated arachidonic acid release independent of Ca2+ and mitogen-activated protein kinase regulation.
Academic Article Stress- and cell type-dependent regulation of transfected c-Jun N-terminal kinase and mitogen-activated protein kinase kinase isoforms.
Academic Article Inhibited neurogenesis in JNK1-deficient embryonic stem cells.
Academic Article Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.
Academic Article Akt negatively regulates the cJun N-terminal kinase pathway in PC12 cells.
Academic Article Antitumorigenic effects of peroxisome proliferator-activated receptor-gamma in non-small-cell lung cancer cells are mediated by suppression of cyclooxygenase-2 via inhibition of nuclear factor-kappaB.
Academic Article Antitumorigenic effect of Wnt 7a and Fzd 9 in non-small cell lung cancer cells is mediated through ERK-5-dependent activation of peroxisome proliferator-activated receptor gamma.
Concept Protein Kinase C
Concept Mitogen-Activated Protein Kinase 8
Concept Mitogen-Activated Protein Kinase Kinases
Concept Mitogen-Activated Protein Kinase 7
Concept Protein Kinase Inhibitors
Concept Mitogen-Activated Protein Kinase 1
Concept Mitogen-Activated Protein Kinase 9
Concept Mitogen-Activated Protein Kinase 10
Concept Mitogen-Activated Protein Kinase 3
Concept Protein Kinase C-delta
Concept Proto-Oncogene Proteins c-akt
Academic Article Heterotrimeric G-protein, Ga16, is a critical downstream effector of non-canonical Wnt signaling and a potent inhibitor of transformed cell growth in non small cell lung cancer.
Academic Article FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies.
Academic Article Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy.
Academic Article An Inducible TGF-?2-TGF?R Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases.
Academic Article FGFR1 Expression Levels Predict BGJ398 Sensitivity of FGFR1-Dependent Head and Neck Squamous Cell Cancers.
Academic Article Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data.
Academic Article Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC.
Academic Article An integrated bioinformatics analysis to dissect kinase dependency in triple negative breast cancer.
Academic Article MERTK as a novel therapeutic target in head and neck cancer.
Academic Article Co-dependency of PKCd and K-Ras: inverse association with cytotoxic drug sensitivity in KRAS mutant lung cancer.
Grant PERSISTENT KINASE SIGNALS IN PC12 CELL DIFFERENTIATION
Academic Article Analysis of Drug Resistance Using Kinome-Wide Functional Screens.
Academic Article Mechanisms of rapid cancer cell reprogramming initiated by targeted receptor tyrosine kinase inhibitors and inherent therapeutic vulnerabilities.
Academic Article Subcellular Localization and Activity of the Mitogen-Activated Protein Kinase Kinase 7 (MKK7) ? Isoform are Regulated through Binding to the Phosphatase Calcineurin.
Academic Article Therapeutic opportunity in innate immune response induction by oncogene-targeted drugs.
Academic Article Functional RNAi Screens Define Distinct Protein Kinase Vulnerabilities in EGFR-Dependent HNSCC Cell Lines.
Academic Article Novel EGFR-mutant mouse models of lung adenocarcinoma reveal adaptive immunity requirement for durable osimertinib response.
Academic Article A functional sgRNA-CRISPR screening method for generating murine RET and NTRK1 rearranged oncogenes.

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