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Search Results to Philip Reigan

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Reigan, Philip

One or more keywords matched the following items that are connected to Reigan, Philip

Item Type	Name
Academic Article	Modification of Akt2 by 4-hydroxynonenal inhibits insulin-dependent Akt signaling in HepG2 cells.
Academic Article	Inhibition of hydrogen peroxide signaling by 4-hydroxynonenal due to differential regulation of Akt1 and Akt2 contributes to decreases in cell survival and proliferation in hepatocellular carcinoma cells.
Concept	MAP Kinase Signaling System
Concept	Ribosomal Protein S6 Kinases, 90-kDa
Concept	Glycogen Synthase Kinase 3
Concept	Protein-Tyrosine Kinases
Concept	Protein Kinase Inhibitors
Concept	Mitogen-Activated Protein Kinase 1
Concept	CDC2 Protein Kinase
Concept	AMP-Activated Protein Kinases
Concept	Mitogen-Activated Protein Kinase 3
Concept	Phosphatidylinositol 3-Kinases
Academic Article	Inhibition of Wee1 sensitizes cancer cells to antimetabolite chemotherapeutics in vitro and in vivo, independent of p53 functionality.
Academic Article	Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.
Academic Article	RSK3: A regulator of pathological cardiac remodeling.
Academic Article	Structure-Based Screen Identification of a Mammalian Ste20-like Kinase 4 (MST4) Inhibitor with Therapeutic Potential for Pituitary Tumors.
Academic Article	A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells.
Academic Article	Targeting WEE1 Kinase in Cancer.
Academic Article	Selective Targeting of RSK Isoforms in Cancer.
Academic Article	Development of Potent Pyrazolopyrimidinone-Based WEE1 Inhibitors with Limited Single-Agent Cytotoxicity for Cancer Therapy.
Grant	Novel small-molecule inhibitors of Wee1 kinase for medulloblastoma treatment
Academic Article	Establishment and Characterization of Four Novel Thyroid Cancer Cell Lines and PDX Models Expressing the RET/PTC1 Rearrangement, BRAFV600E, or RASQ61R as Drivers.
Concept	Glycogen Synthase Kinase 3 beta
Academic Article	Substituted pteridinones as p90 ribosomal S6 protein kinase (RSK) inhibitors: A structure-activity study.
Academic Article	Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors.
Academic Article	Inhibition of BRAF and ERK1/2 has synergistic effects on thyroid cancer growth in vitro and in vivo.
Academic Article	N-Substituted pyrrolopyrimidines and purines as p90 ribosomal S6 protein kinase-2 (RSK2) inhibitors.
Grant	Development of AMPK Inhibitors for the treatment of leukemia
Academic Article	Substituted pteridinones, pyrimidines, pyrrolopyrimidines, and purines as p90 ribosomal S6 protein kinase-2 (RSK2) inhibitors: Pharmacophore modeling data.

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