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Alex Christopher Hughes

TitleAssistant Research Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
ORCID ORCID Icon0000-0001-6083-5884 Additional info

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hughes A.C., Graham, L. S. Treatment Approaches and Future Directions for Neuroendocrine Prostate Cancer and Other Aggressive Variant Prostate Cancers. Advances in Oncology. 2026; 6(1):165-172.
    2. Ogg MC, Lansdell BJ, Franks HT, Hughes AC, Lee J, Nolen HG, Shirinifard A, Schwarz LA. Locus coeruleus norepinephrine neurons facilitate orbitofrontal cortex remapping and behavioral flexibility. Cell Rep. 2025 Dec 23; 44(12):116687. PMID: 41389209.
      View in: PubMed
    3. Becker LJ, Martin MM, Hughes AC, Mulvey B, Kuo CC, Piantadosi SC, Bruchas MR, Martinowich K, Meye FJ, Schwarz LA, Weinshenker D, McCall JG, Riga D. Neuropeptides as transmitters and regulators of the locus coeruleus noradrenergic system. Pharmacol Rev. 2025 Sep; 77(5):100081. PMID: 40749333.
      View in: PubMed
    4. Lee JG, Petraccione J, Trese KA, Hughes AC, Ausec TR, Salzmann-Sullivan M, Su LJ, Kim MT, Roh S, Goodwin AP, Feng FX, Flaig TW, Shields CW. Soft Extrudable Dendritic Particles with Nanostructured Tendrils for Local Adhesion and Drug Release to Bladder Cancers. Adv Mater. 2025 Sep; 37(38):e2505231. PMID: 40611758.
      View in: PubMed
    5. Hughes AC, Pittman BG, Xu B, Gammons JW, Webb CM, Nolen HG, Chapman P, Bikoff JB, Schwarz LA. A single-vector intersectional AAV strategy for interrogating cellular diversity and brain function. Nat Neurosci. 2024 Jul; 27(7):1400-1410. PMID: 38802592.
      View in: PubMed
    6. Perera YR, Xu JX, Amarasekara DL, Hughes AC, Abbood I, Fitzkee NC. Understanding the Adsorption of Peptides and Proteins onto PEGylated Gold Nanoparticles. Molecules. 2021 Sep 24; 26(19). PMID: 34641335.
      View in: PubMed
    7. Perera YR, South TM, Hughes AC, Parkhurst AN, Williams OC, Davidson MB, Wilks CA, Mlsna DA, Fitzkee NC. Using NMR Spectroscopy To Measure Protein Binding Capacity on Gold Nanoparticles. J Chem Educ. 2020 Mar 10; 97(3):820-824. PMID: 34045774.
      View in: PubMed
    8. Martin EW, Holehouse AS, Grace CR, Hughes A, Pappu RV, Mittag T. Sequence Determinants of the Conformational Properties of an Intrinsically Disordered Protein Prior to and upon Multisite Phosphorylation. J Am Chem Soc. 2016 Nov 30; 138(47):15323-15335. PMID: 27807972.
      View in: PubMed
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