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Lynn Marie Pezzanite

TitleAsst Professor Adjoint
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-ORTHO General Operations

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Luedke L, Hendrickson DA, Pezzanite LM, Easley JT. Mitigating and addressing complications in equine laparoscopy. J Am Vet Med Assoc. 2026 Jun 03; 1-9. PMID: 42242281.
      View in: PubMed
    2. Lee S, Hector RC, Pezzanite L, Gilleland E, Rezende ML. Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses. Equine Vet J. 2026 May 04. PMID: 42076924.
      View in: PubMed
    3. Rockow M, Gongaware A, Hendrickson D, Easley J, Luedke L, Pezzanite L. Historical perspectives guide advances in equine minimally invasive soft tissue surgery. J Am Vet Med Assoc. 2026 May 01; 1-11. PMID: 42061445.
      View in: PubMed
    4. Barton CK, Koch TG, Russell KA, Moorhead R, Mehrpouyan S, Alizadeh AH, Dow S, Pezzanite LM, Goodrich LR. Toll-like receptor 3-activated allogeneic umbilical cord blood-derived mesenchymal stromal cells as an adjunct for the treatment of synovial sepsis in 3 horses. J Am Vet Med Assoc. 2026 Apr 17; 1-9. PMID: 41999738.
      View in: PubMed
    5. Winston SE, Janicki J, Serio N, Willis M, Dow S, Wong SW, Puttlitz C, Pezzanite LM, McGilvray KC. Fuzzy-logic-driven predictions of multi-tissue ingrowth for rapid screening of mechanically instructive tissue-engineering scaffolds. Biomed Mater. 2026 Apr 02; 21(2). PMID: 41880771.
      View in: PubMed
    6. Brekhus C, Pezzanite L, McGilvray K, Gadomski B. Science-in-brief: Finite element modelling and mechanical testing techniques in musculoskeletal applications. Equine Vet J. 2026 May; 58(3):658-663. PMID: 41795912.
      View in: PubMed
    7. Horna M, Merchán Muñoz A, Goodrich L, Pezzanite L, Dow S, Koch TR, Alizadeh AH, Mehrpouyan S, Koenig J. Case Report: Equine allogeneic umbilical cord blood mesenchymal stromal cells (CB-MSC) as adjunctive therapy in a foal with septic arthritis and osteomyelitis. Front Vet Sci. 2026; 13:1734585. PMID: 41858542.
      View in: PubMed
    8. Singer J, Chow L, Ammons D, Sabino I, Impastato R, Dow S, Pezzanite LM. Senescence-associated gene pathways are differentially expressed in equine aging-related osteoarthritis. Am J Vet Res. 2026 Apr 01; 87(4). PMID: 41468690.
      View in: PubMed
    9. Winston SE, von Stade D, Chow L, Plaisance C, Impastato R, Dow S, Pezzanite LM, McGilvray K. Incorporation of Pattern Recognition Receptor Agonists in Hydrogels to Induce Rotator Cuff Healing. Tissue Eng Part A. 2025 Dec 08. PMID: 41391944.
      View in: PubMed
    10. Stoner AK, Pezzanite LM, Dow SW, Alfonso NA, McGilvray KC. An In Vitro Assessment of a Biopolymer-Based Medical Foam for Enhanced Antifibrinolytic and Infection Prophylaxis for Acute Wound Management. ACS Appl Bio Mater. 2025 Dec 15; 8(12):10878-10889. PMID: 41252298.
      View in: PubMed
    11. Linde P, Kurihara J, Chow L, Williams ZJ, Hendrickson D, Bass L, Dow S, Pezzanite LM. Identification of Antibodies to Chondrocyte and Synoviocyte Antigens in Equine Osteoarthritis. J Orthop Res. 2025 Dec; 43(12):2152-2164. PMID: 41117710.
      View in: PubMed
    12. Linde P, Chow L, Sabino I, Williams Z, Impastato R, Dow S, Pezzanite L. Innate immune pathway activation to modulate mesenchymal stromal cell (MSC) interactions with synovium and cartilage. Front Bioeng Biotechnol. 2025; 13:1605148. PMID: 40861855.
      View in: PubMed
    13. Pezzanite LM, Le-Bert C, Lutmerding E, Meegan J, DiRocco S, Robeck T, Hendrickson DA. Advancement of laparoscopic-guided abdominal approaches in cetacean species. J Am Vet Med Assoc. 2025 11 01; 263(11):1-2. PMID: 40769195.
      View in: PubMed
    14. Lee SH, Lu R, House A, Li Z, Burton LH, Sikes KJ, Pezzanite LM, Koch DW, Labus KM, Gadomski B, Easley J, Tran RT, Heo SC. Anionic Citrate-Based 3D-Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration. Adv Funct Mater. 2025 Nov 19; 35(47). PMID: 41727733.
      View in: PubMed
    15. Plaisance C, Chow L, Impastato R, Williams ZJ, Sabino I, Sikes KJ, Santangelo KS, Dow S, Pezzanite LM. Innate immune pathway activated mesenchymal stromal cells improve function and histologic outcomes in a rodent osteoarthritis model. Front Bioeng Biotechnol. 2025; 13:1525969. PMID: 40474870.
      View in: PubMed
    16. Marcolina M, Williams ZJ, Hendrickson D, Pezzanite LM. Evaluation of Sterility of Saline Formulations Manufactured for Wound Care in Veterinary Practice. Vet Sci. 2025 Apr 30; 12(5). PMID: 40431524.
      View in: PubMed
    17. Hendesi H, Villani DA, Prawitt J, Gill AL, Abdo Z, Santangelo KS, Pezzanite L, Gill SR, Zuscik MJ. Gut and Joint Microbiomes: Implications in Osteoarthritis. Rheum Dis Clin North Am. 2025 05; 51(2):295-324. PMID: 40246442.
      View in: PubMed
    18. Pezzanite LM, Nelson BB, Downey AC, Gadomski B, McGilvray K, Baer K, Kappel SM, Nout-Lomas Y, Seim HB, Easley JT. Ex vivo biomechanical comparison of pedicle screw and rod constructs with and without interbody fusion devices for equine cervical vertebral stabilization. Vet Surg. 2025 Apr; 54(3):610-620. PMID: 39953786.
      View in: PubMed
    19. Chow L, Kawahisa-Piquini G, Bass L, Hendrickson D, Patel A, Rockow M, Dow S, Pezzanite LM. Correlation of fecal microbiome dysregulation to synovial transcriptome in an equine model of obesity associated osteoarthritis. Ann Transl Med. 2024 Dec 24; 12(6):112. PMID: 39817240.
      View in: PubMed
    20. Seabaugh K, Rao S, Koenig JB, Pezzanite L, Dow S, Koch TG, Russell KA, Mehrpouyan S, Alizadeh AH, Goodrich LR. A Pilot Study to Assess the Safety and Efficacy of Umbilical Cord Blood-Derived Mesenchymal Stromal Cells for the Treatment of Synovitis in Horses. Animals (Basel). 2024 Nov 26; 14(23). PMID: 39682372.
      View in: PubMed
    21. Ammons DT, Chow L, Goodrich L, Bass L, Larson B, Williams ZJ, Stoneback JW, Dow S, Pezzanite LM. Characterization of the single cell landscape in normal and osteoarthritic equine joints. Ann Transl Med. 2024 Oct 20; 12(5):88. PMID: 39507442.
      View in: PubMed
    22. Pezzanite L. Clinical insights: Regenerative therapies in equine practice: Top 10 EVJ papers 2019-2024. Equine Vet J. 2024 Sep; 56(5):824-831. PMID: 39113179.
      View in: PubMed
    23. Williams ZJ, Pezzanite LM, Chow L, Rockow M, Dow SW. Evaluation of stem-cell therapies in companion animal disease models: a concise review (2015-2023). Stem Cells. 2024 08 01; 42(8):677-705. PMID: 38795363.
      View in: PubMed
    24. Pezzanite L, Barrachina L, Schnabel L. Editorial: Links between regenerative medicine and immunotherapy: how cellular therapies modulate immune responses for improved outcomes. Front Vet Sci. 2024; 11:1462218. PMID: 39132432.
      View in: PubMed
    25. Williams ZJ, Chow L, Dow S, Pezzanite LM. The potential for senotherapy as a novel approach to extend life quality in veterinary medicine. Front Vet Sci. 2024; 11:1369153. PMID: 38812556.
      View in: PubMed
    26. Chow L, Flaherty E, Pezzanite L, Williams M, Dow S, Wotman K. Impact of Equine Ocular Surface Squamous Neoplasia on Interactions between Ocular Transcriptome and Microbiome. Vet Sci. 2024 Apr 07; 11(4). PMID: 38668434.
      View in: PubMed
    27. Williams ZJ, Pezzanite LM, Hendrickson DA. Review of skin grafting in equine wounds: indications and techniques. Equine Vet Educ. 2024 Sep; 36(9):484-493. PMID: 39246829.
      View in: PubMed
    28. Pezzanite LM, Chow L, Engiles JB, Kurihara J, Plaisance C, Goodrich LR, Dow S. Targeted transcriptomic analysis of synovial tissues from horses with septic arthritis treated with immune-activated mesenchymal stromal cells reveals induction of T-cell response pathways. J Am Vet Med Assoc. 2024 06 01; 262(S1):S73-S82. PMID: 38295517.
      View in: PubMed
    29. Cassano JM, Leonard BC, Martins BC, Vapniarsky N, Morgan JT, Dow SW, Wotman KL, Pezzanite LM. Preliminary evaluation of safety and migration of immune activated mesenchymal stromal cells administered by subconjunctival injection for equine recurrent uveitis. Front Vet Sci. 2023; 10:1293199. PMID: 38162475.
      View in: PubMed
    30. Rockow M, Griffenhagen G, Landolt G, Hendrickson D, Pezzanite L. The Effects of Antimicrobial Protocols and Other Perioperative Factors on Postoperative Complications in Horses Undergoing Celiotomy: A Retrospective Analysis, 2008-2021. Animals (Basel). 2023 Nov 19; 13(22). PMID: 38003189.
      View in: PubMed
    31. Webster A, Pezzanite L, Hendrickson D, Griffenhagen G. Review of intra-articular local anaesthetic administration in horses: Clinical indications, cytotoxicity, and outcomes. Equine Vet J. 2024 Sep; 56(5):870-883. PMID: 37940372.
      View in: PubMed
    32. Thampi P, Seabaugh KA, Pezzanite LM, Chu CR, Phillips JN, Grieger JC, McIlwraith CW, Samulski RJ, Goodrich LR. A pilot study to determine the optimal dose of scAAVIL-1ra in a large animal model of post-traumatic osteoarthritis. Gene Ther. 2023 12; 30(12):792-800. PMID: 37696981.
      View in: PubMed
    33. Pezzanite LM, Chow L, Dow SW, Goodrich LR, Gilbertie JM, Schnabel LV. Antimicrobial Properties of Equine Stromal Cells and Platelets and Future Directions. Vet Clin North Am Equine Pract. 2023 Dec; 39(3):565-578. PMID: 37442729.
      View in: PubMed
    34. Pezzanite LM, Timkovich AE, Sikes KJ, Chow L, Hendrickson DA, Becker JR, Webster A, Santangelo KS, Dow S. Erythrocyte removal from bone marrow aspirate concentrate improves efficacy as intra-articular cellular therapy in a rodent osteoarthritis model. Ann Transl Med. 2023 Jun 30; 11(9):311. PMID: 37404993.
      View in: PubMed
    35. Rockow M, Griffenhagen G, Landolt G, Hendrickson D, Pezzanite L. Current Antimicrobial Use in Horses Undergoing Exploratory Celiotomy: A Survey of Board-Certified Equine Specialists. Animals (Basel). 2023 Apr 22; 13(9). PMID: 37174470.
      View in: PubMed
    36. Kawahisa-Piquini G, Bass L, Pezzanite LM, Moorman VJ. Hoof Unevenness in Juvenile Quarter Horses During First 6 Months of Training. J Equine Vet Sci. 2023 07; 126:104494. PMID: 37075868.
      View in: PubMed
    37. O'Brien TJ, Pezzanite LM, Acutt EV, Vilander AC, Hassel DM, Hector RC, Hendrickson DA. Successful surgical removal of a pheochromocytoma in a mare via trans-costal approach. Equine Vet J. 2023 Nov; 55(6):1012-1020. PMID: 36754850.
      View in: PubMed
    38. Pezzanite LM, Chow L, Griffenhagen GM, Bass L, Goodrich LR, Impastato R, Dow S. Distinct differences in immunological properties of equine orthobiologics revealed by functional and transcriptomic analysis using an activated macrophage readout system. Front Vet Sci. 2023; 10:1109473. PMID: 36876001.
      View in: PubMed
    39. Kawahisa-Piquini G, Bass LD, Pezzanite LM, Moorman VJ. Effect of age at training initiation on hoof morphology and lameness in juvenile American Quarter Horses. Equine Vet J. 2023 Sep; 55(5):765-776. PMID: 36572927.
      View in: PubMed
    40. Pezzanite LM, Griffenhagen GM, Bass L, Okudaira M, Larson B, Hendrickson DA. Liposomal bupivacaine is both safe and effective when administered via local infiltration at surgical site and mesovarium for laparoscopic ovariectomy in mares. Equine Vet J. 2023 Sep; 55(5):755-764. PMID: 36572902.
      View in: PubMed
    41. Wotman KL, Chow L, Martabano B, Pezzanite LM, Dow S. Novel ocular immunotherapy induces tumor regression in an equine model of ocular surface squamous neoplasia. Cancer Immunol Immunother. 2023 May; 72(5):1185-1198. PMID: 36367558.
      View in: PubMed
    42. Pezzanite LM, Chow L, Strumpf A, Johnson V, Dow SW. Immune Activated Cellular Therapy for Drug Resistant Infections: Rationale, Mechanisms, and Implications for Veterinary Medicine. Vet Sci. 2022 Nov 04; 9(11). PMID: 36356087.
      View in: PubMed
    43. Pezzanite LM, Chow L, Phillips J, Griffenhagen GM, Moore AR, Schaer TP, Engiles JB, Werpy N, Gilbertie J, Schnabel LV, Antczak D, Miller D, Dow S, Goodrich LR. TLR-activated mesenchymal stromal cell therapy and antibiotics to treat multi-drug resistant Staphylococcal septic arthritis in an equine model. Ann Transl Med. 2022 Nov; 10(21):1157. PMID: 36467344.
      View in: PubMed
    44. Afzali MF, Pannone SC, Martinez RB, Campbell MA, Sanford JL, Pezzanite LM, Kurihara J, Johnson V, Dow SW, Santangelo KS. Intravenous injection of adipose-derived mesenchymal stromal cells benefits gait and inflammation in a spontaneous osteoarthritis model. J Orthop Res. 2023 04; 41(4):902-912. PMID: 36030381.
      View in: PubMed
    45. Daniels A, Pezzanite LM, Griffenhagen GM, Hendrickson DA. Evaluation of factors associated with surgical site infection in equine proximal interphalangeal joint arthrodesis: 54 cases (2010-2019). Vet Med Sci. 2022 07; 8(4):1478-1488. PMID: 35594487.
      View in: PubMed
    46. Moorman VJ, Pezzanite LM, Griffenhagen GM. Liposomal bupivacaine provides longer duration analgesia than bupivacaine hydrochloride in an adjustable sole-pressure model of equine lameness. Am J Vet Res. 2022 Jan 28; 83(4):298-304. PMID: 35092669.
      View in: PubMed
    47. Estrada McDermott J, Pezzanite L, Goodrich L, Santangelo K, Chow L, Dow S, Wheat W. Role of Innate Immunity in Initiation and Progression of Osteoarthritis, with Emphasis on Horses. Animals (Basel). 2021 Nov 13; 11(11). PMID: 34827979.
      View in: PubMed
    48. Pezzanite LM, Hendrickson DA, Dow S, Stoneback J, Chow L, Krause D, Goodrich L. Intra-articular administration of antibiotics in horses: Justifications, risks, reconsideration of use and outcomes. Equine Vet J. 2022 Jan; 54(1):24-38. PMID: 34459027.
      View in: PubMed
    49. Pezzanite LM, Hackett ES, McCready E, Easley JT. Outcomes following single, caudally based bilateral versus unilateral frontonasal sinusotomy for treatment of equine paranasal sinus disease. Vet Med Sci. 2021 11; 7(6):2209-2218. PMID: 34405566.
      View in: PubMed
    50. Krause DM, Pezzanite LM, Griffenhagen GM, Hendrickson DA. Comparison of equine synovial sepsis rate following intrasynovial injection in ambulatory versus hospital settings. Equine Vet J. 2022 May; 54(3):523-530. PMID: 34115426.
      View in: PubMed
    51. Pezzanite L, Chow L, Hendrickson D, Gustafson DL, Russell Moore A, Stoneback J, Griffenhagen GM, Piquini G, Phillips J, Lunghofer P, Dow S, Goodrich LR. Evaluation of Intra-Articular Amikacin Administration in an Equine Non-inflammatory Joint Model to Identify Effective Bactericidal Concentrations While Minimizing Cytotoxicity. Front Vet Sci. 2021; 8:676774. PMID: 34095281.
      View in: PubMed
    52. Pezzanite LM, Easley JT, Bayless R, Aldrich E, Nelson BB, Seim HB, Nout-Lomas YS. Outcomes after cervical vertebral interbody fusion using an interbody fusion device and polyaxial pedicle screw and rod construct in 10 horses (2015-2019). Equine Vet J. 2022 Mar; 54(2):347-358. PMID: 33844334.
      View in: PubMed
    53. Pezzanite L, Chow L, Griffenhagen G, Dow S, Goodrich L. Impact of Three Different Serum Sources on Functional Properties of Equine Mesenchymal Stromal Cells. Front Vet Sci. 2021; 8:634064. PMID: 33996964.
      View in: PubMed
    54. Pezzanite LM, Chow L, Johnson V, Griffenhagen GM, Goodrich L, Dow S. Toll-like receptor activation of equine mesenchymal stromal cells to enhance antibacterial activity and immunomodulatory cytokine secretion. Vet Surg. 2021 May; 50(4):858-871. PMID: 33797775.
      View in: PubMed
    55. Newman RJ, Chow L, Goodrich LR, Lambrechts NE, Dow SW, Pezzanite LM. Susceptibility of canine chondrocytes and synoviocytes to antibiotic cytotoxicity in vitro. Vet Surg. 2021 Apr; 50(3):650-658. PMID: 33606293.
      View in: PubMed
    56. Pezzanite LM, Griffenhagen GM, Krause DM, Hendrickson DA. Retrospective evaluation of association between perioperative antimicrobial protocol and complications following elective equine synovial endoscopy. Vet Med Sci. 2021 05; 7(3):609-620. PMID: 33595201.
      View in: PubMed
    57. Pezzanite L, Chow L, Piquini G, Griffenhagen G, Ramirez D, Dow S, Goodrich L. Use of in vitro assays to identify antibiotics that are cytotoxic to normal equine chondrocytes and synovial cells. Equine Vet J. 2021 May; 53(3):579-589. PMID: 32544273.
      View in: PubMed
    58. Pezzanite L, Chow L, Soontararak S, Phillips J, Goodrich L, Dow S. Amikacin induces rapid dose-dependent apoptotic cell death in equine chondrocytes and synovial cells in vitro. Equine Vet J. 2020 Sep; 52(5):715-724. PMID: 31997397.
      View in: PubMed
    59. Pezzanite L, Easley J. Update on Surgical Treatment of Wobblers. Vet Clin North Am Equine Pract. 2019 Aug; 35(2):299-309. PMID: 31147149.
      View in: PubMed
    60. Pezzanite L, Bass L, Kawcak C, Goodrich L, Moorman V. The relationship between sagittal hoof conformation and hindlimb lameness in the horse. Equine Vet J. 2019 Jul; 51(4):464-469. PMID: 30472759.
      View in: PubMed
    61. Pezzanite LM, Hackett ES. Technique-associated outcomes in horses following large colon resection. Vet Surg. 2017 Nov; 46(8):1061-1067. PMID: 28987065.
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    62. White HM, Carvalho ER, Koser SL, Schmelz-Roberts NS, Pezzanite LM, Slabaugh AC, Doane PH, Donkin SS. Short communication: Regulation of hepatic gluconeogenic enzymes by dietary glycerol in transition dairy cows. J Dairy Sci. 2016 Jan; 99(1):812-7. PMID: 26547649.
      View in: PubMed
    63. Pezzanite LM, Fortier LA, Antczak DF, Cassano JM, Brosnahan MM, Miller D, Schnabel LV. Equine allogeneic bone marrow-derived mesenchymal stromal cells elicit antibody responses in vivo. Stem Cell Res Ther. 2015 Apr 12; 6:54. PMID: 25889095.
      View in: PubMed
    64. Schnabel LV, Pezzanite LM, Antczak DF, Felippe MJ, Fortier LA. Equine bone marrow-derived mesenchymal stromal cells are heterogeneous in MHC class II expression and capable of inciting an immune response in vitro. Stem Cell Res Ther. 2014 Jan 24; 5(1):13. PMID: 24461709.
      View in: PubMed
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