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Patrick Scott Hume

TitleAffiliate - NJH
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

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    K08HL155894     (HUME, PATRICK SCOTT)Jan 1, 2022 - Dec 31, 2026
    NIH
    Interstitial macrophages in cigarette smoke-induced small airway remodeling
    Role: Principal Investigator
    F32HL145900     (HUME, PATRICK SCOTT)Jul 1, 2019 - Jun 30, 2020
    NIH
    Stereologic Localization of Interstitial Macrophages in the Lungs of Smokers and Nonsmokers
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Malcolm KC, Ochoa AE, Congel JH, Hume PS, Corley JM, Wheeler EA, Bai X, Nick JA, Janssen WJ, Chan ED, Cool CD, Hisert KB. A Murine Model of Mycobacterium abscessus Infection Mimics Pathology of Chronic Human Lung Disease. Am J Respir Cell Mol Biol. 2025 May; 72(5):591-594. PMID: 39589263.
      View in: PubMed
    2. Hara N, Raclawska DS, Morgan LE, NeeDell JC, Dao L, Kato A, Jaramillo AM, Hume PS, Holguin F, Janssen WJ, Vladar EK, Evans CM. Requirement for Fucosyltransferase 2 in Allergic Airway Hyperreactivity and Mucus Obstruction. Am J Respir Cell Mol Biol. 2025 Apr; 72(4):408-417. PMID: 39447136.
      View in: PubMed
    3. Skillin NP, Kirkpatrick BE, Friend NE, Perry AR, McCracken JM, Escobar MC, Nelson BR, Day NL, Hume PS, Rajab TK, Anseth KS, White TJ. In vivo photothermal reconfiguration of liquid crystalline elastomer nanocomposites. Cell Biomater. 2025 Mar 25; 1(2). PMID: 40144640.
      View in: PubMed
    4. Zheng J, Dhakal H, Qing E, Shrestha R, Geller AE, Morrissey SM, Saxena D, Hu X, Li H, Li H, Wilhelmsen K, Wendt LH, Klumpp K, Hume PS, Janssen WJ, Brody R, Palmer KE, Uriarte SM, Ten Eyck P, Meyerholz DK, Merchant ML, McLeish K, Gallagher T, Huang J, Yan J, Perlman S. CXCL12 ameliorates neutrophilia and disease severity in SARS-CoV-2 infection. J Clin Invest. 2025 Jan 07; 135(4). PMID: 39773555.
      View in: PubMed
    5. Chakraborty S, Cheng BY, Edwards DL, Gonzalez JC, Chiu DK, Zheng H, Scallan C, Guo X, Tan GS, Coffey GP, Conley PB, Hume PS, Janssen WJ, Byers DE, Mudd PA, Taubenberger J, Memoli M, Davis MM, Chua KF, Diamond MS, Andreakos E, Khatri P, Wang TT. Sialylated IgG induces the transcription factor REST in alveolar macrophages to protect against lung inflammation and severe influenza disease. Immunity. 2025 Jan 14; 58(1):182-196.e10. PMID: 39541970.
      View in: PubMed
    6. Hynds RE, Magin CM, Ikonomou L, Aschner Y, Beers MF, Burgess JK, Heise RL, Hume PS, Krasnodembskaya AD, Mei SHJ, Misharin AV, Park JA, Reynolds SD, Tschumperlin DJ, Tanneberger AE, Vaidyanathan S, Waters CM, Zettler PJ, Weiss DJ, Ryan AL. Stem cells, cell therapies, and bioengineering in lung biology and diseases 2023. Am J Physiol Lung Cell Mol Physiol. 2024 Sep 01; 327(3):L327-L340. PMID: 38772903.
      View in: PubMed
    7. Blomberg R, Sompel K, Hauer C, Smith AJ, Pe?a B, Driscoll J, Hume PS, Merrick DT, Tennis MA, Magin CM. Hydrogel-Embedded Precision-Cut Lung Slices Model Lung Cancer Premalignancy Ex Vivo. Adv Healthc Mater. 2024 02; 13(4):e2302246. PMID: 37953708.
      View in: PubMed
    8. Palmer WH, Leaton LA, Campos Codo A, Crute B, Roest J, Zhu S, Petersen J, Tobin RP, Hume PS, Stone M, van Bokhoven A, Gerich ME, McCarter MD, Zhu Y, Janssen WJ, Vivian JP, Trowsdale J, Getahun A, Rossjohn J, Cambier J, Loh L, Norman PJ. Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells. Sci Immunol. 2023 06 30; 8(84):eade5343. PMID: 37390222.
      View in: PubMed
    9. Petrache I, Pujadas E, Ganju A, Serban KA, Borowiec A, Babbs B, Bronova IA, Egersdorf N, Hume PS, Goel K, Janssen WJ, Berdyshev EV, Cordon-Cardo C, Kolesnick R. Marked elevations in lung and plasma ceramide in COVID-19 linked to microvascular injury. JCI Insight. 2023 05 22; 8(10). PMID: 37212278.
      View in: PubMed
    10. Petrache I, Gupta A, Hume PS, Rivera T, Schweitzer KS, Chu HW. Pathogenesis of E-Cigarette Vaping Product Use-Associated Lung Injury (EVALI). Compr Physiol. 2023 03 30; 13(2):4617-4630. PMID: 36994770.
      View in: PubMed
    11. Blomberg R, Sompel K, Hauer C, Pe A B, Driscoll J, Hume PS, Merrick DT, Tennis MA, Magin CM. Tissue-engineered models of lung cancer premalignancy. bioRxiv. 2023 Mar 16. PMID: 36993773.
      View in: PubMed
    12. Hume PS, McClendon J, Kopf KW, Harral JW, Poczobutt JM, McCubbrey AL, Smith BJ, Henson PM, Majka SM, Petrache I, Janssen WJ. Cigarette smoke-induced airspace disease in mice develops independently of HIF-1a signaling in leukocytes. Am J Physiol Lung Cell Mol Physiol. 2022 10 01; 323(4):L391-L399. PMID: 35943156.
      View in: PubMed
    13. Mattson CL, Okamura K, Hume PS, Smith BJ. Spatiotemporal distribution of cellular injury and leukocytes during the progression of ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2022 09 01; 323(3):L281-L296. PMID: 35700201.
      View in: PubMed
    14. Xu J, Xu L, Sui P, Chen J, Moya EA, Hume P, Janssen WJ, Duran JM, Thistlethwaite P, Carlin A, Gulleman P, Banaschewski B, Goldy MK, Yuan JX, Malhotra A, Pryhuber G, Crotty-Alexander L, Deutsch G, Young LR, Sun X. Excess neuropeptides in lung signal through endothelial cells to impair gas exchange. Dev Cell. 2022 04 11; 57(7):839-853.e6. PMID: 35303432.
      View in: PubMed
    15. King EM, Hume PS, Janssen WJ, McCubbrey AL. Isolation and Analysis of Macrophage Subsets from the Mouse and Human Lung. Methods Mol Biol. 2022; 2506:257-267. PMID: 35771477.
      View in: PubMed
    16. Thomas SM, Bednarek J, Janssen WJ, Hume PS. Air-Inflation of Murine Lungs with Vascular Perfusion-Fixation. J Vis Exp. 2021 02 02; (168). PMID: 33616116.
      View in: PubMed
    17. Hume PS, Gibbings SL, Jakubzick CV, Tuder RM, Curran-Everett D, Henson PM, Smith BJ, Janssen WJ. Localization of Macrophages in the Human Lung via Design-based Stereology. Am J Respir Crit Care Med. 2020 05 15; 201(10):1209-1217. PMID: 32197050.
      View in: PubMed
    18. Files DC, Hume PS, Krall J, Montemayor K, Schmidt EP, King LS. Grant Writing for Clinicians in Training: An Important Career Development Exercise. Chest. 2020 04; 157(4):932-935. PMID: 31730834.
      View in: PubMed
    19. Hume PS, Varon J, Englert JA, Hurwitz S, Klompas M, Baron RM, Rhee C. Trends in "usual care" for septic shock. Infect Control Hosp Epidemiol. 2018 09; 39(9):1125-1126. PMID: 30022742.
      View in: PubMed
    20. Hume PS, He J, Haskins K, Anseth KS. Strategies to reduce dendritic cell activation through functional biomaterial design. Biomaterials. 2012 May; 33(14):3615-25. PMID: 22361099.
      View in: PubMed
    21. Hume PS, Anseth KS. Polymerizable superoxide dismutase mimetic protects cells encapsulated in poly(ethylene glycol) hydrogels from reactive oxygen species-mediated damage. J Biomed Mater Res A. 2011 Oct; 99(1):29-37. PMID: 21793194.
      View in: PubMed
    22. Hume PS, Bowman CN, Anseth KS. Functionalized PEG hydrogels through reactive dip-coating for the formation of immunoactive barriers. Biomaterials. 2011 Sep; 32(26):6204-12. PMID: 21658759.
      View in: PubMed
    23. Hume PS, Anseth KS. Inducing local T cell apoptosis with anti-Fas-functionalized polymeric coatings fabricated via surface-initiated photopolymerizations. Biomaterials. 2010 Apr; 31(12):3166-74. PMID: 20138358.
      View in: PubMed
    24. Leiske DL, Karimpour-Fard A, Hume PS, Fairbanks BD, Gill RT. A comparison of alternative 60-mer probe designs in an in-situ synthesized oligonucleotide microarray. BMC Genomics. 2006 Apr 04; 7:72. PMID: 16595014.
      View in: PubMed
    25. Bonomo J, Warnecke T, Hume P, Marizcurrena A, Gill RT. A comparative study of metabolic engineering anti-metabolite tolerance in Escherichia coli. Metab Eng. 2006 May; 8(3):227-39. PMID: 16497527.
      View in: PubMed
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