 Pentoxifylline
"Pentoxifylline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
| Descriptor ID |
D010431
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| MeSH Number(s) |
D03.633.100.759.758.824.651.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pentoxifylline".
Below are MeSH descriptors whose meaning is more specific than "Pentoxifylline".
This graph shows the total number of publications written about "Pentoxifylline" by people in this website by year, and whether "Pentoxifylline" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 | | 1996 | 1 | 1 | 2 | | 1997 | 3 | 0 | 3 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 2 | 2 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pentoxifylline" by people in Profiles.
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Nahm WJ, Mota JA, Rojas S, Hizon BJ, Gordon C. Improvement of Ulcerations in Treatment-Resistant Chronic Scarring in a Patient with Pyoderma Gangrenosum After Improving Vascular Insufficiency, Gently Removing Necrotic Debris, and Decreasing Wound Fluid. Am J Case Rep. 2018 Jul 19; 19:844-848.
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Creager MA, Pande RL, Hiatt WR. A randomized trial of iloprost in patients with intermittent claudication. Vasc Med. 2008 Feb; 13(1):5-13.
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Regensteiner JG, Stewart KJ. Established and evolving medical therapies for claudication in patients with peripheral arterial disease. Nat Clin Pract Cardiovasc Med. 2006 Nov; 3(11):604-10.
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Costelli P, Muscaritoli M, Bossola M, Penna F, Reffo P, Bonetto A, Busquets S, Bonelli G, Lopez-Soriano FJ, Doglietto GB, Argil?s JM, Baccino FM, Rossi Fanelli F. IGF-1 is downregulated in experimental cancer cachexia. Am J Physiol Regul Integr Comp Physiol. 2006 Sep; 291(3):R674-83.
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Kyle PB, Adcock KG, Kramer RE, Baker RC. Use of liquid chromatography-tandem mass spectrometry for the analysis of pentoxifylline and lisofylline in plasma. Biomed Chromatogr. 2005 Apr; 19(3):231-6.
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Regensteiner JG, Hiatt WR. Current medical therapies for patients with peripheral arterial disease: a critical review. Am J Med. 2002 Jan; 112(1):49-57.
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Hiatt WR. New treatment options in intermittent claudication: the US experience. Int J Clin Pract Suppl. 2001 Apr; (119):20-7.
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Dawson DL, Cutler BS, Hiatt WR, Hobson RW, Martin JD, Bortey EB, Forbes WP, Strandness DE. A comparison of cilostazol and pentoxifylline for treating intermittent claudication. Am J Med. 2000 Nov; 109(7):523-30.
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Briggs WA, Wu Q, Orgul O, Choi M, Scheel PJ, Burdick J. Lymphocyte suppression by rolipram with other immunosuppressive drugs. J Clin Pharmacol. 1999 Aug; 39(8):794-9.
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Briggs WA, Eustace J, Mathew S, Gimenez LF, Choi M, Scheel PJ, Burdick J. Pentoxifylline potentiates in vitro lymphocyte suppression by glucocorticoids and immunosuppressive drugs. J Clin Pharmacol. 1998 Jun; 38(6):561-6.
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