 Polypharmacy
"Polypharmacy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The use of multiple drugs administered to the same patient, most commonly seen in elderly patients. It includes also the administration of excessive medication. Since in the United States most drugs are dispensed as single-agent formulations, polypharmacy, though using many drugs administered to the same patient, must be differentiated from DRUG COMBINATIONS, single preparations containing two or more drugs as a fixed dose, and from DRUG THERAPY, COMBINATION, two or more drugs administered separately for a combined effect. (From Segen, Dictionary of Modern Medicine, 1992)
| Descriptor ID |
D019338
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| MeSH Number(s) |
E02.319.698
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polypharmacy".
Below are MeSH descriptors whose meaning is more specific than "Polypharmacy".
This graph shows the total number of publications written about "Polypharmacy" by people in this website by year, and whether "Polypharmacy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 0 | 2 | 2 | | 2015 | 5 | 2 | 7 | | 2016 | 3 | 3 | 6 | | 2017 | 1 | 1 | 2 | | 2018 | 2 | 1 | 3 | | 2019 | 4 | 2 | 6 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 2 | 4 | | 2022 | 2 | 6 | 8 | | 2023 | 2 | 4 | 6 |
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Below are the most recent publications written about "Polypharmacy" by people in Profiles.
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Page RL, Chow SL. Polypharmacy and the Clinical Inertia?Conundrum for GDMT. JACC Heart Fail. 2023 11; 11(11):1518-1520.
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Green AR, Weffald LA, Powers JD, Drace ML, Norton JD, Boyd CM, Bayliss EA. Assessing medication appropriateness as a deprescribing outcome. J Am Geriatr Soc. 2023 12; 71(12):3918-3920.
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Dangerfield HJ, Scott JM, Zohn JH, Segal DL, Benton MJ. Relationship between anxiety and quality of life among older adults with self-reported polypharmacy in long-term care: A cross-sectional study. J Adv Nurs. 2023 Sep; 79(9):3559-3568.
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Orth LE, Feudtner C, Kempe A, Morris MA, Colborn KL, Gritz RM, Linnebur SA, Begum A, Feinstein JA. A coordinated approach for managing polypharmacy among children with medical complexity: rationale and design of the Pediatric Medication Therapy Management (pMTM) randomized controlled trial. BMC Health Serv Res. 2023 Apr 29; 23(1):414.
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Reeve E, Bayliss EA, Shetterly S, Maiyani M, Gleason KS, Norton JD, Sheehan OC, Green AR, Maciejewski ML, Drace M, Sawyer J, Boyd CM. Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed. Age Ageing. 2023 01 08; 52(1).
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Kyler KE, Hall M, Antoon JW, Goldman J, Grijalva CG, Shah SS, Tang Girdwood S, Williams DJ, Feinstein JA. Polypharmacy among medicaid-insured children with and without documented obesity. Pharmacotherapy. 2023 07; 43(7):588-595.
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Sheehan OC, Gleason KS, Bayliss EA, Green AR, Drace ML, Norton J, Reeve E, Shetterly SM, Weffald LA, Sawyer JK, Maciejewski ML, Kraus C, Maiyani M, Wolff J, Boyd CM. Intervention design in cognitively impaired populations-Lessons learned from the OPTIMIZE deprescribing pragmatic trial. J Am Geriatr Soc. 2023 03; 71(3):774-784.
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Feinstein JA, Orth LE. Making Polypharmacy Safer for Children with Medical Complexity. J Pediatr. 2023 03; 254:4-10.
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Hung A, Sloan CE, Boyd C, Bayliss EA, Hastings SN, Maciejewski ML. Deprescribing medications: Do out-of-pocket costs have a role? J Am Geriatr Soc. 2022 11; 70(11):3334-3337.
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Goyal P, Safford MM, Hilmer SN, Steinman MA, Matlock DD, Maurer MS, Lachs MS, Kronish IM. N-of-1 trials to facilitate evidence-based deprescribing: Rationale and case study. Br J Clin Pharmacol. 2022 10; 88(10):4460-4473.
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