 Rats, Zucker
"Rats, Zucker" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Two populations of Zucker rats have been cited in research--the "fatty" or obese and the lean. The "fatty" rat (Rattus norvegicus) appeared as a spontaneous mutant. The obese condition appears to be due to a single recessive gene.
| Descriptor ID |
D011924
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| MeSH Number(s) |
B01.050.150.900.649.313.992.635.505.700.550.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Rats, Zucker".
Below are MeSH descriptors whose meaning is more specific than "Rats, Zucker".
This graph shows the total number of publications written about "Rats, Zucker" by people in this website by year, and whether "Rats, Zucker" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 3 | 3 | | 2006 | 0 | 4 | 4 | | 2007 | 0 | 3 | 3 | | 2008 | 0 | 2 | 2 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Rats, Zucker" by people in Profiles.
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Rochester E, Wickman BE, Bell A, Simecka C, Clayton ZS, Hakkak R, Hooshmand S. A diet containing high- versus low-daidzein does not affect bone density and osteogenic gene expression in the obese Zucker rat model. Food Funct. 2019 Oct 16; 10(10):6851-6857.
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Mason McClatchey P, Wu F, Olfert IM, Ellis CG, Goldman D, Reusch JEB, Frisbee JC. Impaired Tissue Oxygenation in Metabolic Syndrome Requires Increased Microvascular Perfusion Heterogeneity. J Cardiovasc Transl Res. 2017 Feb; 10(1):69-81.
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Qin L, Chong T, Rodriguez R, Pugazhenthi S. Glucagon-Like Peptide-1-Mediated Modulation of Inflammatory Pathways in the Diabetic Brain: Relevance to Alzheimer's Disease. Curr Alzheimer Res. 2016; 13(12):1346-1355.
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Koh GY, Derscheid R, Fuller KNZ, Valentine RJ, Leow SE, Reed L, Wisecup E, Schalinske KL, Rowling MJ. Circulating adiponectin concentrations are increased by dietary resistant starch and correlate with serum 25-hydroxycholecalciferol concentrations and kidney function in Zucker diabetic fatty rats. Nutr Res. 2016 Apr; 36(4):311-319.
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Pugazhenthi S, Qin L, Bouchard R. Dipeptidyl peptidase-4 inhibition in diabetic rats leads to activation of the transcription factor CREB in ?-cells. Eur J Pharmacol. 2015 May 15; 755:42-9.
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Tiriveedhi V, Conzen KD, Liaw-Conlin J, Upadhya G, Malone J, Townsend RR, Kerns R, Jia J, Csontos K, Ramachandran S, Mohanakumar T, Anderson CD, Chapman WC. The role of molecular chaperonins in warm ischemia and reperfusion injury in the steatotic liver: a proteomic study. BMC Biochem. 2012 Sep 10; 13:17.
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Anderson CD, Upadhya G, Conzen KD, Jia J, Brunt EM, Tiriveedhi V, Xie Y, Ramachandran S, Mohanakumar T, Davidson NO, Chapman WC. Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts. Liver Transpl. 2011 Feb; 17(2):189-200.
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Diamond-Stanic MK, Marchionne EM, Teachey MK, Durazo DE, Kim JS, Henriksen EJ. Critical role of the transient activation of p38 MAPK in the etiology of skeletal muscle insulin resistance induced by low-level in vitro oxidant stress. Biochem Biophys Res Commun. 2011 Feb 18; 405(3):439-44.
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Thyfault JP, Cree MG, Tapscott EB, Bell JA, Koves TR, Ilkayeva O, Wolfe RR, Dohm GL, Muoio DM. Metabolic profiling of muscle contraction in lean compared with obese rodents. Am J Physiol Regul Integr Comp Physiol. 2010 Sep; 299(3):R926-34.
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Archuleta TL, Lemieux AM, Saengsirisuwan V, Teachey MK, Lindborg KA, Kim JS, Henriksen EJ. Oxidant stress-induced loss of IRS-1 and IRS-2 proteins in rat skeletal muscle: role of p38 MAPK. Free Radic Biol Med. 2009 Nov 15; 47(10):1486-93.
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