Apolipoprotein E3
"Apolipoprotein E3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 34-kDa glycosylated protein. A major and most common isoform of apolipoprotein E. Therefore, it is also known as apolipoprotein E (ApoE). In human, Apo E3 is a 299-amino acid protein with a cysteine at the 112 and an arginine at the 158 position. It is involved with the transport of TRIGLYCERIDES; PHOSPHOLIPIDS; CHOLESTEROL; and CHOLESTERYL ESTERS in and out of the cells.
Descriptor ID |
D053318
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MeSH Number(s) |
D10.532.091.500.500 D12.776.070.400.500.500 D12.776.521.120.500.500
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Concept/Terms |
Apolipoprotein E3- Apolipoprotein E3
- Apo E3
- APOE-epsilon 3
- APOE epsilon 3
- Isoapolipoprotein E3
- ApoE3
- Apolipoprotein E-3
- Apolipoprotein E 3
- Apolipoprotein E-epsilon3
- Apolipoprotein E epsilon3
- Apo E-3
- Apo E 3
- APOE-epsilon3
- APOE epsilon3
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Below are MeSH descriptors whose meaning is more general than "Apolipoprotein E3".
Below are MeSH descriptors whose meaning is more specific than "Apolipoprotein E3".
This graph shows the total number of publications written about "Apolipoprotein E3" by people in this website by year, and whether "Apolipoprotein E3" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 1 | 0 | 1 | 2014 | 0 | 1 | 1 | 2018 | 0 | 1 | 1 | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apolipoprotein E3" by people in Profiles.
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Chang S, Torii S, Inamo J, Ishikawa K, Kochi Y, Shimizu S. Uncovering the Localization and Function of a Novel Read-Through Transcript 'TOMM40-APOE'. Cells. 2023 12 28; 13(1).
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Main BS, Villapol S, Sloley SS, Barton DJ, Parsadanian M, Agbaegbu C, Stefos K, McCann MS, Washington PM, Rodriguez OC, Burns MP. Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury. Mol Neurodegener. 2018 04 04; 13(1):17.
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Gale SC, Gao L, Mikacenic C, Coyle SM, Rafaels N, Murray Dudenkov T, Madenspacher JH, Draper DW, Ge W, Aloor JJ, Azzam KM, Lai L, Blackshear PJ, Calvano SE, Barnes KC, Lowry SF, Corbett S, Wurfel MM, Fessler MB. APOe4 is associated with enhanced in vivo innate immune responses in human subjects. J Allergy Clin Immunol. 2014 Jul; 134(1):127-34.
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Schepers A, de Vries MR, van Leuven CJ, Grimbergen JM, Holers VM, Daha MR, van Bockel JH, Quax PH. Inhibition of complement component C3 reduces vein graft atherosclerosis in apolipoprotein E3-Leiden transgenic mice. Circulation. 2006 Dec 19; 114(25):2831-8.
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