 Thienamycins
"Thienamycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.
| Descriptor ID |
D013845
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| MeSH Number(s) |
D02.065.589.099.124.300 D03.633.100.300.124.300
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| Concept/Terms |
Thienamycins- Thienamycins
- Antibiotics, Thienamycin
- Thienamycin Antibiotics
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Below are MeSH descriptors whose meaning is more general than "Thienamycins".
Below are MeSH descriptors whose meaning is more specific than "Thienamycins".
This graph shows the total number of publications written about "Thienamycins" by people in this website by year, and whether "Thienamycins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thienamycins" by people in Profiles.
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Singh AK, Thakare R, Karaulia P, Das S, Soni I, Pandey M, Pandey AK, Chopra S, Dasgupta A. Biological evaluation of diphenyleneiodonium chloride (DPIC) as a potential drug candidate for treatment of non-tuberculous mycobacterial infections. J Antimicrob Chemother. 2017 Nov 01; 72(11):3117-3121.
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Prince BT, McMahon BJ, Jain M, Peters AT. Meropenem tolerance in a patient with probable fulminant piperacillin-induced immune hemolytic anemia. J Allergy Clin Immunol Pract. 2015 May-Jun; 3(3):452-3.
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Lee AB, Harker-Murray P, Ferrieri P, Schleiss MR, Tolar J. Bacterial meningitis from Rothia mucilaginosa in patients with malignancy or undergoing hematopoietic stem cell transplantation. Pediatr Blood Cancer. 2008 Mar; 50(3):673-6.
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Obritsch MD, Fish DN, MacLaren R, Jung R. Nosocomial infections due to multidrug-resistant Pseudomonas aeruginosa: epidemiology and treatment options. Pharmacotherapy. 2005 Oct; 25(10):1353-64.
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Fish DN, Singletary TJ. Meropenem, a new carbapenem antibiotic. Pharmacotherapy. 1997 Jul-Aug; 17(4):644-69.
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