 Papaverine
"Papaverine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
| Descriptor ID |
D010208
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| MeSH Number(s) |
D03.132.098.666 D03.132.577.750 D03.633.100.531.085.666
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Papaverine".
Below are MeSH descriptors whose meaning is more specific than "Papaverine".
This graph shows the total number of publications written about "Papaverine" by people in this website by year, and whether "Papaverine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Papaverine" by people in Profiles.
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Asgari SA, Asli MM, Madani AH, Maghsoudi PA, Ghanaei MM, Shakiba M, Aval HB, Enshaei A, Farzan A, Esmaeili S. Treatment of loin pain suspected to be renal colic with papaverine hydrochloride: a prospective double-blind randomised study. BJU Int. 2012 Aug; 110(3):449-52.
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Lamm WJ, Obermiller T, Hlastala MP, Albert RK. Perfusion through vessels open in zone 1 contributes to gas exchange in rabbit lungs in situ. J Appl Physiol (1985). 1995 Dec; 79(6):1895-9.
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Lamm WJ, Luchtel D, Albert RK. Sites of leakage in three models of acute lung injury. J Appl Physiol (1985). 1988 Mar; 64(3):1079-83.
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Linas SL, Shanley PF, White CW, Parker NP, Repine JE. O2 metabolite-mediated injury in perfused kidneys is reflected by consumption of DMTU and glutathione. Am J Physiol. 1987 Oct; 253(4 Pt 2):F692-701.
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