 Leukocyte Common Antigens
"Leukocyte Common Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.
| Descriptor ID |
D017493
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| MeSH Number(s) |
D08.811.277.352.650.775.400.100.500 D12.644.360.587.100.500 D12.776.476.592.100.500 D12.776.543.733.937.500
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| Concept/Terms |
Leukocyte Common Antigens- Leukocyte Common Antigens
- Antigens, Leukocyte Common
- CD45 Antigens
- Antigens, CD45
- Protein Tyrosine Phosphatase, Receptor Type, C
- L-CA Antigens
- Antigens, L-CA
- L CA Antigens
- Leukocyte Common Antigen
- Antigen, Leukocyte Common
- CD45 Antigen
- Antigen, CD45
- T200 Antigens
- Antigens, T200
CD45RO Antigens- CD45RO Antigens
- Antigens, CD45RO
- CD45R0 Antigens
- Antigens, CD45R0
B220 Antigens- B220 Antigens
- Antigens, B220
- CD45R Antigens
- Antigens, CD45R
- B220 Antigen
- Antigen, B220
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Below are MeSH descriptors whose meaning is more general than "Leukocyte Common Antigens".
Below are MeSH descriptors whose meaning is more specific than "Leukocyte Common Antigens".
This graph shows the total number of publications written about "Leukocyte Common Antigens" by people in this website by year, and whether "Leukocyte Common Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 1997 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 3 | 4 | | 2005 | 0 | 5 | 5 | | 2006 | 1 | 3 | 4 | | 2007 | 0 | 3 | 3 | | 2008 | 0 | 3 | 3 | | 2009 | 0 | 2 | 2 | | 2010 | 1 | 0 | 1 | | 2011 | 2 | 3 | 5 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 4 | 5 | | 2014 | 0 | 3 | 3 | | 2015 | 2 | 3 | 5 | | 2016 | 0 | 3 | 3 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 | | 2020 | 0 | 3 | 3 | | 2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "Leukocyte Common Antigens" by people in Profiles.
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Palanki R, Riley JS, Bose SK, Luks V, Dave A, Kus N, White BM, Ricciardi AS, Swingle KL, Xue L, Sung D, Thatte AS, Safford HC, Chaluvadi VS, Carpenter M, Han EL, Maganti R, Hamilton AG, Mrksich K, Billingsley MB, Zoltick PW, Alameh MG, Weissman D, Mitchell MJ, Peranteau WH. In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells. Proc Natl Acad Sci U S A. 2024 Aug 06; 121(32):e2400783121.
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Shumate KA, Williams SN, Khatri AB, Knight V. Addition of CD14 improves discrimination of lymphocytes in the TBNK phenotyping panel. Cytometry B Clin Cytom. 2024 Sep; 106(5):347-358.
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Ryan CE, Salvetti TR, Baum IR, Figueroa BA, LeBere BE, Alberti MO. Single-tube Ptprc SNP genotyping of JAXBoy (CD45.1) and C57BL/6J (CD45.2) mice by endpoint PCR and gel electrophoresis. Mol Cell Probes. 2024 Jun; 75:101962.
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Boyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM, Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG. Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020 11; 587(7834):466-471.
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Kasam RK, Gajjala PR, Jegga AG, Courtney JA, Randell SH, Kramer EL, Clancy JP, Madala SK. Fibrocyte accumulation in the lungs of cystic fibrosis patients. J Cyst Fibros. 2020 09; 19(5):815-822.
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Kim AJ, Xu N, Umeyama K, Hulin A, Ponny SR, Vagnozzi RJ, Green EA, Hanson P, McManus BM, Nagashima H, Yutzey KE. Deficiency of Circulating Monocytes Ameliorates the Progression of Myxomatous Valve Degeneration in Marfan Syndrome. Circulation. 2020 01 14; 141(2):132-146.
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Triplett BM, Muller B, Kang G, Li Y, Cross SJ, Moen J, Cunningham L, Janssen W, Mamcarz E, Shook DR, Srinivasan A, Choi J, Hayden RT, Leung W. Selective T-cell depletion targeting CD45RA reduces viremia and enhances early T-cell recovery compared with CD3-targeted T-cell depletion. Transpl Infect Dis. 2018 Feb; 20(1).
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Culbertson CJ, Lummus SC, Gold CA. Teaching NeuroImages: Myeloperoxidase-anti-neutrophil cytoplasmic antibody-positive hypertrophic pachymeningitis. Neurology. 2017 11 21; 89(21):e253.
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Futia GL, Schlaepfer IR, Qamar L, Behbakht K, Gibson EA. Statistical performance of image cytometry for DNA, lipids, cytokeratin, & CD45 in a model system for circulation tumor cell detection. Cytometry A. 2017 07; 91(7):662-674.
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Leelatian N, Doxie DB, Greenplate AR, Mobley BC, Lehman JM, Sinnaeve J, Kauffmann RM, Werkhaven JA, Mistry AM, Weaver KD, Thompson RC, Massion PP, Hooks MA, Kelley MC, Chambless LB, Ihrie RA, Irish JM. Single cell analysis of human tissues and solid tumors with mass cytometry. Cytometry B Clin Cytom. 2017 01; 92(1):68-78.
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