 Leukocyte Common Antigens
"Leukocyte Common Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.
| Descriptor ID |
D017493
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| MeSH Number(s) |
D08.811.277.352.650.775.400.100.500 D12.644.360.587.100.500 D12.776.476.592.100.500 D12.776.543.733.937.500
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| Concept/Terms |
Leukocyte Common Antigens- Leukocyte Common Antigens
- Antigens, Leukocyte Common
- CD45 Antigens
- Antigens, CD45
- Protein Tyrosine Phosphatase, Receptor Type, C
- L-CA Antigens
- Antigens, L-CA
- L CA Antigens
- Leukocyte Common Antigen
- Antigen, Leukocyte Common
- CD45 Antigen
- Antigen, CD45
- T200 Antigens
- Antigens, T200
CD45RO Antigens- CD45RO Antigens
- Antigens, CD45RO
- CD45R0 Antigens
- Antigens, CD45R0
B220 Antigens- B220 Antigens
- Antigens, B220
- CD45R Antigens
- Antigens, CD45R
- B220 Antigen
- Antigen, B220
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Below are MeSH descriptors whose meaning is more general than "Leukocyte Common Antigens".
Below are MeSH descriptors whose meaning is more specific than "Leukocyte Common Antigens".
This graph shows the total number of publications written about "Leukocyte Common Antigens" by people in this website by year, and whether "Leukocyte Common Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 1997 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 3 | 4 | | 2005 | 0 | 5 | 5 | | 2006 | 1 | 2 | 3 | | 2007 | 0 | 2 | 2 | | 2008 | 0 | 3 | 3 | | 2009 | 0 | 2 | 2 | | 2010 | 1 | 0 | 1 | | 2011 | 2 | 3 | 5 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 3 | 4 | | 2014 | 0 | 3 | 3 | | 2015 | 2 | 3 | 5 | | 2016 | 0 | 3 | 3 | | 2017 | 1 | 1 | 2 | | 2020 | 0 | 2 | 2 | | 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Leukocyte Common Antigens" by people in Profiles.
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Shumate KA, Williams SN, Khatri AB, Knight V. Addition of CD14 improves discrimination of lymphocytes in the TBNK phenotyping panel. Cytometry B Clin Cytom. 2024 Sep; 106(5):347-358.
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Ryan CE, Salvetti TR, Baum IR, Figueroa BA, LeBere BE, Alberti MO. Single-tube Ptprc SNP genotyping of JAXBoy (CD45.1) and C57BL/6J (CD45.2) mice by endpoint PCR and gel electrophoresis. Mol Cell Probes. 2024 Jun; 75:101962.
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Boyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM, Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG. Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020 11; 587(7834):466-471.
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Kim AJ, Xu N, Umeyama K, Hulin A, Ponny SR, Vagnozzi RJ, Green EA, Hanson P, McManus BM, Nagashima H, Yutzey KE. Deficiency of Circulating Monocytes Ameliorates the Progression of Myxomatous Valve Degeneration in Marfan Syndrome. Circulation. 2020 01 14; 141(2):132-146.
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Culbertson CJ, Lummus SC, Gold CA. Teaching NeuroImages: Myeloperoxidase-anti-neutrophil cytoplasmic antibody-positive hypertrophic pachymeningitis. Neurology. 2017 11 21; 89(21):e253.
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Futia GL, Schlaepfer IR, Qamar L, Behbakht K, Gibson EA. Statistical performance of image cytometry for DNA, lipids, cytokeratin, & CD45 in a model system for circulation tumor cell detection. Cytometry A. 2017 07; 91(7):662-674.
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Leelatian N, Doxie DB, Greenplate AR, Mobley BC, Lehman JM, Sinnaeve J, Kauffmann RM, Werkhaven JA, Mistry AM, Weaver KD, Thompson RC, Massion PP, Hooks MA, Kelley MC, Chambless LB, Ihrie RA, Irish JM. Single cell analysis of human tissues and solid tumors with mass cytometry. Cytometry B Clin Cytom. 2017 01; 92(1):68-78.
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Moutsoglou DM, Dreskin SC. B cells establish, but do not maintain, long-lived murine anti-peanut IgE(a). Clin Exp Allergy. 2016 Apr; 46(4):640-53.
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Fu Q, Colgan SP, Shelley CS. Hypoxia: The Force that Drives Chronic Kidney Disease. Clin Med Res. 2016 Mar; 14(1):15-39.
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Kuban-Jankowska A, Gorska M, Jaremko L, Jaremko M, Tuszynski JA, Wozniak M. The physiological concentration of ferrous iron (II) alters the inhibitory effect of hydrogen peroxide on CD45, LAR and PTP1B phosphatases. Biometals. 2015 Dec; 28(6):975-86.
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