 Chondrosarcoma
"Chondrosarcoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A slowly growing malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and old people. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion or in patients with ENCHONDROMATOSIS. (Stedman, 25th ed)
| Descriptor ID |
D002813
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| MeSH Number(s) |
C04.557.450.565.280 C04.557.450.795.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chondrosarcoma".
Below are MeSH descriptors whose meaning is more specific than "Chondrosarcoma".
This graph shows the total number of publications written about "Chondrosarcoma" by people in this website by year, and whether "Chondrosarcoma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 2 | 0 | 2 | | 2015 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 | | 2024 | 1 | 0 | 1 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Chondrosarcoma" by people in Profiles.
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Tap WD, Cote GM, Burris H, Gore L, Elias A, Beeram M, Conley AP, Gianolio DA, Qu Z, Pandya S, Trent JC. Phase I Study of the Mutant IDH1 Inhibitor Ivosidenib: Long-term Safety and Clinical Activity in Patients with Conventional Chondrosarcoma. Clin Cancer Res. 2025 Jun 03; 31(11):2108-2114.
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Saisuwan K, Boonnate P, Goto H, Nakagawa R, Abe M, Hirabayashi K, Fujiwara Y, Kikuta K, Okada S. Establishment and characterization of TK-DDCS1: a novel IDH1 mutated dedifferentiated chondrosarcoma cell line. Hum Cell. 2025 Jun 03; 38(4):116.
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Li L, Hashemi L, Eid J, Tao W, Campoverde L, Yu A, Farooqi AA, Al-Ali H, D'Amato G, Hornicek F, Duan Z, Lohse I, Trent J. High-Throughput Drug Screening in Chondrosarcoma Cells Identifies Effective Antineoplastic Agents Independent of IDH Mutation. Int J Mol Sci. 2024 Dec 03; 25(23).
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Subbiah V, Chawla SP, Conley AP, Wilky BA, Tolcher A, Lakhani NJ, Berz D, Andrianov V, Crago W, Holcomb M, Hussain A, Veldstra C, Kalabus J, O'Neill B, Senne L, Rowell E, Heidt AB, Willis KM, Eckelman BP. Preclinical Characterization and Phase I Trial Results of INBRX-109, A Third-Generation, Recombinant, Humanized, Death Receptor 5 Agonist Antibody, in Chondrosarcoma. Clin Cancer Res. 2023 08 15; 29(16):2988-3003.
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Toland AMS, Lam SW, Varma S, Wang A, Howitt BE, Kunder CA, Kerr DA, Szuhai K, Bovée JVMG, Charville GW. GRM1 Immunohistochemistry Distinguishes Chondromyxoid Fibroma From its Histologic Mimics. Am J Surg Pathol. 2022 10 01; 46(10):1407-1414.
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Tap WD, Villalobos VM, Cote GM, Burris H, Janku F, Mir O, Beeram M, Wagner AJ, Jiang L, Wu B, Choe S, Yen K, Gliser C, Fan B, Agresta S, Pandya SS, Trent JC. Phase I Study of the Mutant IDH1 Inhibitor Ivosidenib: Safety and Clinical Activity in Patients With Advanced Chondrosarcoma. J Clin Oncol. 2020 05 20; 38(15):1693-1701.
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Hinchcliff KM, Crockett J, Thorpe SW, Bayne CO. Using a kidney pump to perfuse a free filet flap for reconstruction after hemipelvectomy: A case report. Microsurgery. 2019 Feb; 39(2):178-181.
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Beswick DM, Damrose EJ. Primary tracheoesophageal puncture and cricopharyngeal myotomy in stapler-assisted total laryngectomy. J Laryngol Otol. 2016 Jul; 130(7):686-90.
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Li L, Paz AC, Wilky BA, Johnson B, Galoian K, Rosenberg A, Hu G, Tinoco G, Bodamer O, Trent JC. Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells. PLoS One. 2015; 10(9):e0133813.
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Tinoco G, Wilky BA, Paz-Mejia A, Rosenberg A, Trent JC. The biology and management of cartilaginous tumors: a role for targeting isocitrate dehydrogenase. Am Soc Clin Oncol Educ Book. 2015; e648-55.
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