TYK2 Kinase
"TYK2 Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The TYK2 kinase is considered the founding member of the janus kinase family and was initially discovered as a signaling partner for the INTERFERON ALPHA-BETA RECEPTOR. The kinase has since been shown to signal from several INTERLEUKIN RECEPTORS.
| Descriptor ID |
D053634
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| MeSH Number(s) |
D08.811.913.696.620.682.725.124.650 D12.776.476.393.650
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| Concept/Terms |
TYK2 Kinase- TYK2 Kinase
- Kinase, TYK2
- Non-Receptor Tyrosine-Protein Kinase TYK2
- Non Receptor Tyrosine Protein Kinase TYK2
- Tyrosine Kinase 2
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Below are MeSH descriptors whose meaning is more general than "TYK2 Kinase".
Below are MeSH descriptors whose meaning is more specific than "TYK2 Kinase".
This graph shows the total number of publications written about "TYK2 Kinase" by people in this website by year, and whether "TYK2 Kinase" was a major or minor topic of these publications.
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Below are the most recent publications written about "TYK2 Kinase" by people in Profiles.
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Geiger TR, Martin JM. The Epstein-Barr virus-encoded LMP-1 oncoprotein negatively affects Tyk2 phosphorylation and interferon signaling in human B cells. J Virol. 2006 Dec; 80(23):11638-50.
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Lukashova V, Chen Z, Duh? RJ, Rola-Pleszczynski M, Stankov? J. Janus kinase 2 activation by the platelet-activating factor receptor (PAFR): roles of Tyk2 and PAFR C terminus. J Immunol. 2003 Oct 01; 171(7):3794-800.