Cushing Syndrome
"Cushing Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
Descriptor ID |
D003480
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MeSH Number(s) |
C19.053.800.367
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Concept/Terms |
Cushing Syndrome- Cushing Syndrome
- Syndrome, Cushing
- Cushing's Syndrome
- Syndrome, Cushing's
- Hypercortisolism
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Below are MeSH descriptors whose meaning is more general than "Cushing Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Cushing Syndrome".
This graph shows the total number of publications written about "Cushing Syndrome" by people in this website by year, and whether "Cushing Syndrome" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 | 2006 | 1 | 0 | 1 | 2007 | 1 | 0 | 1 | 2009 | 2 | 0 | 2 | 2010 | 1 | 0 | 1 | 2011 | 1 | 0 | 1 | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cushing Syndrome" by people in Profiles.
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Pivonello R, Bancos I, Feelders RA, Kargi AY, Kerr JM, Gordon MB, Mariash CN, Terzolo M, Ellison N, Moraitis AG. Relacorilant, a Selective Glucocorticoid Receptor Modulator, Induces Clinical Improvements in Patients With Cushing Syndrome: Results From A Prospective, Open-Label Phase 2 Study. Front Endocrinol (Lausanne). 2021; 12:662865.
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Lodish MB, Gourgari E, Sinaii N, Hill S, Libuit L, Mastroyannis S, Keil M, Batista DL, Stratakis CA. Skeletal maturation in children with Cushing syndrome is not consistently delayed: the role of corticotropin, obesity, and steroid hormones, and the effect of surgical cure. J Pediatr. 2014 Apr; 164(4):801-6.
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Bentley L, Esapa CT, Nesbit MA, Head RA, Evans H, Lath D, Scudamore CL, Hough TA, Podrini C, Hannan FM, Fraser WD, Croucher PI, Brown MA, Brown SD, Cox RD, Thakker RV. An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess. Endocrinology. 2014 Mar; 155(3):908-22.
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Donner NC, Montoya CD, Lukkes JL, Lowry CA. Chronic non-invasive corticosterone administration abolishes the diurnal pattern of tph2 expression. Psychoneuroendocrinology. 2012 May; 37(5):645-61.
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Reimondo G, Allasino B, Bovio S, Saba L, Ardito A, Angeli A, Terzolo M. Pros and cons of dexamethasone suppression test for screening of subclinical Cushing's syndrome in patients with adrenal incidentalomas. J Endocrinol Invest. 2011 Jan; 34(1):e1-5.
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Cree MG, Paddon-Jones D, Newcomer BR, Ronsen O, Aarsland A, Wolfe RR, Ferrando A. Twenty-eight-day bed rest with hypercortisolemia induces peripheral insulin resistance and increases intramuscular triglycerides. Metabolism. 2010 May; 59(5):703-10.
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Moriarty M, Hoe F. Cushing disease in a toddler: not all obese children are just fat. Curr Opin Pediatr. 2009 Aug; 21(4):548-52.
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Dovio A, Allasino B, Palmas E, Ventura M, Pia A, Saba L, Aroasio E, Terzolo M, Angeli A. Increased osteoprotegerin levels in Cushing's syndrome are associated with an adverse cardiovascular risk profile. J Clin Endocrinol Metab. 2007 May; 92(5):1803-8.
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Salvatori R, Fintini D, Westra WH, Cho SY, Schulick RD. Cushing's Syndrome attributable to ectopic secretion of corticotropin in a patient with two neuroendocrine tumors. Endocr Pract. 2006 Nov-Dec; 12(6):656-9.
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Lopez JA, Kleinschmidt-Demasters Bk Bk, Sze CI, Woodmansee WW, Lillehei KO. Silent corticotroph adenomas: further clinical and pathological observations. Hum Pathol. 2004 Sep; 35(9):1137-47.
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