Adenosine A2 Receptor Antagonists
"Adenosine A2 Receptor Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that selectively bind to and block the activation of ADENOSINE A2 RECEPTORS.
Descriptor ID |
D058917
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MeSH Number(s) |
D27.505.519.625.725.400.100.200 D27.505.696.577.725.400.100.200
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Adenosine A2 Receptor Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Adenosine A2 Receptor Antagonists".
This graph shows the total number of publications written about "Adenosine A2 Receptor Antagonists" by people in this website by year, and whether "Adenosine A2 Receptor Antagonists" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 0 | 1 | 2006 | 0 | 1 | 1 | 2008 | 1 | 0 | 1 | 2010 | 0 | 1 | 1 | 2012 | 1 | 1 | 2 | 2014 | 0 | 1 | 1 | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Adenosine A2 Receptor Antagonists" by people in Profiles.
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Haynes NS, O'Neill CE, Hobson BD, Bachtell RK. Effects of adenosine A2A receptor antagonists on cocaine-induced locomotion and cocaine seeking. Psychopharmacology (Berl). 2019 Feb; 236(2):699-708.
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Zhang Y, Knight W, Chen S, Mohan A, Yan C. Multiprotein Complex With TRPC (Transient Receptor Potential-Canonical) Channel, PDE1C (Phosphodiesterase 1C), and A2R (Adenosine A2 Receptor) Plays a Critical Role in Regulating Cardiomyocyte cAMP and Survival. Circulation. 2018 10 30; 138(18):1988-2002.
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Aherne CM, Collins CB, Rapp CR, Olli KE, Perrenoud L, Jedlicka P, Bowser JL, Mills TW, Karmouty-Quintana H, Blackburn MR, Eltzschig HK. Coordination of ENT2-dependent adenosine transport and signaling dampens mucosal inflammation. JCI Insight. 2018 10 18; 3(20).
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O'Neill CE, Hobson BD, Levis SC, Bachtell RK. Persistent reduction of cocaine seeking by pharmacological manipulation of adenosine A1 and A 2A receptors during extinction training in rats. Psychopharmacology (Berl). 2014 Aug; 231(16):3179-88.
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Page RL, Spurck P, Bainbridge JL, Michalek J, Quaife RA. Seizures associated with regadenoson: a case series. J Nucl Cardiol. 2012 Apr; 19(2):389-91.
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Warren CA, Calabrese GM, Li Y, Pawlowski SW, Figler RA, Rieger J, Ernst PB, Linden J, Guerrant RL. Effects of adenosine A2A receptor activation and alanyl-glutamine in Clostridium difficile toxin-induced ileitis in rabbits and cecitis in mice. BMC Infect Dis. 2012 Jan 20; 12:13.
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Garcia GE, Truong LD, Chen JF, Johnson RJ, Feng L. Adenosine A(2A) receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation. Kidney Int. 2011 Aug; 80(4):378-88.
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Schingnitz U, Hartmann K, Macmanus CF, Eckle T, Zug S, Colgan SP, Eltzschig HK. Signaling through the A2B adenosine receptor dampens endotoxin-induced acute lung injury. J Immunol. 2010 May 01; 184(9):5271-9.
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Eckle T, Grenz A, Laucher S, Eltzschig HK. A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice. J Clin Invest. 2008 Oct; 118(10):3301-15.
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Grenz A, Osswald H, Eckle T, Yang D, Zhang H, Tran ZV, Klingel K, Ravid K, Eltzschig HK. The reno-vascular A2B adenosine receptor protects the kidney from ischemia. PLoS Med. 2008 Jun 24; 5(6):e137.
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