beta-Arrestin 1
"beta-Arrestin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-arrestin that functions in the down-regulation of signaling by G-PROTEIN-COUPLED RECEPTORS. It is also a major regulator of INSULIN signaling via the ERK 1-2 PATHWAY, and many other signaling processes, especially in NEURONS and LEUKOCYTES.
Descriptor ID |
D000071559
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MeSH Number(s) |
D12.644.360.024.098.525.500 D12.776.157.057.005.525.500 D12.776.476.024.104.525.500 D12.776.543.090.525.500
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Concept/Terms |
beta-Arrestin 1- beta-Arrestin 1
- beta Arrestin 1
- Arrestin-2
- Arrestin 2
- Arrestin, beta 1
- beta 1 Arrestin
- ARRB1 Protein
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Below are MeSH descriptors whose meaning is more general than "beta-Arrestin 1".
Below are MeSH descriptors whose meaning is more specific than "beta-Arrestin 1".
This graph shows the total number of publications written about "beta-Arrestin 1" by people in this website by year, and whether "beta-Arrestin 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2010 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta-Arrestin 1" by people in Profiles.
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Kamal FA, Travers JG, Blaxall BC. Embracing bias: ?1-adrenergic receptor-biased ligands and nuclear miRNA processing. Circ Res. 2014 Feb 28; 114(5):742-5.
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Khan SY, McLaughlin NJ, Kelher MR, Eckels P, Gamboni-Robertson F, Banerjee A, Silliman CC. Lysophosphatidylcholines activate G2A inducing G(ai)?1-/G(aq/)11- Ca?(+) flux, G(??)-Hck activation and clathrin/?-arrestin-1/GRK6 recruitment in PMNs. Biochem J. 2010 Nov 15; 432(1):35-45.
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Bawolak MT, Fortin S, Bouthillier J, Adam A, Gera L, C-Gaudreault R, Marceau F. Effects of inactivation-resistant agonists on the signalling, desensitization and down-regulation of bradykinin B(2) receptors. Br J Pharmacol. 2009 Nov; 158(5):1375-86.
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McLaughlin NJ, Banerjee A, Kelher MR, Gamboni-Robertson F, Hamiel C, Sheppard FR, Moore EE, Silliman CC. Platelet-activating factor-induced clathrin-mediated endocytosis requires beta-arrestin-1 recruitment and activation of the p38 MAPK signalosome at the plasma membrane for actin bundle formation. J Immunol. 2006 Jun 01; 176(11):7039-50.
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Kule CE, Karoor V, Day JN, Thomas WG, Baker KM, Dinh D, Acker KA, Booz GW. Agonist-dependent internalization of the angiotensin II type one receptor (AT1): role of C-terminus phosphorylation in recruitment of beta-arrestins. Regul Pept. 2004 Aug 15; 120(1-3):141-8.
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