Podosomes
"Podosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Actin-rich adhesive structures found at the ventral surface of metazoan ENDOTHELIAL CELLS. When found in cultured cancer cells they are referred to as invadopodia. These are matrix-degrading structures composed of an ACTIN CYTOSKELETON core and an INTEGRINS-containing ring complex.
| Descriptor ID |
D000069261
|
| MeSH Number(s) |
A11.284.180.695 A11.436.275.841
|
| Concept/Terms |
Podosomes- Podosomes
- Podosome
- Invadopodium
- Invadopodiums
- Invadopodia
- Invadosomes
- Invadosome
|
Below are MeSH descriptors whose meaning is more general than "Podosomes".
Below are MeSH descriptors whose meaning is more specific than "Podosomes".
This graph shows the total number of publications written about "Podosomes" by people in this website by year, and whether "Podosomes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Podosomes" by people in Profiles.
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Shin DS, Schroeder ME, Anseth KS. Impact of Collagen Triple Helix Structure on Melanoma Cell Invadopodia Formation and Matrix Degradation upon BRAF Inhibitor Treatment. Adv Healthc Mater. 2022 04; 11(7):e2101592.
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Jacob A, Linklater E, Bayless BA, Lyons T, Prekeris R. The role and regulation of Rab40b-Tks5 complex during invadopodia formation and cancer cell invasion. J Cell Sci. 2016 12 01; 129(23):4341-4353.