 Cytochrome P-450 CYP1B1
"Cytochrome P-450 CYP1B1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly.
| Descriptor ID |
D065633
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| MeSH Number(s) |
D08.244.453.005.500 D08.244.453.100.875 D08.811.682.690.708.170.010.500 D08.811.682.690.708.170.020.875 D12.776.422.220.453.010.500 D12.776.422.220.453.100.875
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| Concept/Terms |
Cytochrome P-450 CYP1B1- Cytochrome P-450 CYP1B1
- Cytochrome P 450 CYP1B1
- Cytochrome P450, Family 1, Subfamily B, Polypeptide 1
- Cytochrome P4501B1
- Cytochrome P450 CYP1B1
- P450 CYP1B1, Cytochrome
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Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP1B1".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP1B1".
This graph shows the total number of publications written about "Cytochrome P-450 CYP1B1" by people in this website by year, and whether "Cytochrome P-450 CYP1B1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 2 | 2 | | 2017 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytochrome P-450 CYP1B1" by people in Profiles.
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Lee O, Fought AJ, Shidfar A, Heinz RE, Kmiecik TE, Gann PH, Khan SA, Chatterton RT. Association of genetic polymorphisms with local steroid metabolism in human benign breasts. Steroids. 2022 01; 177:108937.
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Al-Naamani N, Krowka MJ, Forde KA, Krok KL, Feng R, Heresi GA, Dweik RA, Bartolome S, Bull TM, Roberts KE, Austin ED, Hemnes AR, Patel MJ, Oh JK, Lin G, Doyle MF, Denver N, Andrew R, MacLean MR, Fallon MB, Kawut SM. Estrogen Signaling and Portopulmonary Hypertension: The Pulmonary Vascular Complications of Liver Disease Study (PVCLD2). Hepatology. 2021 02; 73(2):726-737.
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Tran HT, Tran HT, Luong LH, Nguyen TS, Nguyen HQ, Vu TT, Ta TD, Dao TMA, Bui TH, Ta TV, Tran VK. Primary congenital glaucoma in Vietnam: analysis and identification of novel CYP1B1 variants. Ophthalmic Genet. 2019 06; 40(3):286-287.
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Bauer AK, Velmurugan K, Pl?ttner S, Siegrist KJ, Romo D, Welge P, Br?ning T, Xiong KN, K?fferlein HU. Environmentally prevalent polycyclic aromatic hydrocarbons can elicit co-carcinogenic properties in an in vitro murine lung epithelial cell model. Arch Toxicol. 2018 Mar; 92(3):1311-1322.
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Martin YN, Manlove L, Dong J, Carey WA, Thompson MA, Pabelick CM, Pandya HC, Martin RJ, Wigle DA, Prakash YS. Hyperoxia-induced changes in estradiol metabolism in postnatal airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15; 308(2):L141-6.
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Jia Y, Domenico J, Swasey C, Wang M, Gelfand EW, Lucas JJ. Modulated expression of genes encoding estrogen metabolizing enzymes by G1-phase cyclin-dependent kinases 6 and 4 in human breast cancer cells. PLoS One. 2014; 9(5):e97448.
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Vyhlidal CA, Riffel AK, Haley KJ, Sharma S, Dai H, Tantisira KG, Weiss ST, Leeder JS. Cotinine in human placenta predicts induction of gene expression in fetal tissues. Drug Metab Dispos. 2013 Feb; 41(2):305-11.
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Butts SF, Freeman EW, Sammel MD, Queen K, Lin H, Rebbeck TR. Joint effects of smoking and gene variants involved in sex steroid metabolism on hot flashes in late reproductive-age women. J Clin Endocrinol Metab. 2012 Jun; 97(6):E1032-42.
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Wang J, Joshi AD, Corral R, Siegmund KD, Marchand LL, Martinez ME, Haile RW, Ahnen DJ, Sandler RS, Lance P, Stern MC. Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk. Int J Cancer. 2012 Apr 15; 130(8):1898-907.
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Taioli E, Im A, Xu X, Veenstra TD, Ahrendt G, Garte S. Comparison of estrogens and estrogen metabolites in human breast tissue and urine. Reprod Biol Endocrinol. 2010 Aug 02; 8:93.
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