 Matrix Metalloproteinase Inhibitors
"Matrix Metalloproteinase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit the enzyme activity or activation of MATRIX METALLOPROTEINASES.
| Descriptor ID |
D061965
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| MeSH Number(s) |
D27.505.519.389.745.610
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Matrix Metalloproteinase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Matrix Metalloproteinase Inhibitors".
This graph shows the total number of publications written about "Matrix Metalloproteinase Inhibitors" by people in this website by year, and whether "Matrix Metalloproteinase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2005 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2010 | 2 | 0 | 2 | | 2014 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Matrix Metalloproteinase Inhibitors" by people in Profiles.
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Agraval H, Kandhari K, Yadav UCS. MMPs as potential molecular targets in epithelial-to-mesenchymal transition driven COPD progression. Life Sci. 2024 Sep 01; 352:122874.
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Kim TI, Kostiuk V, Olson SL, Curci JA, Matsumura JS, Baxter BT, Blackwelder WC, Terrin ML, Guzman RJ. Effect of Doxycycline on Progression of Arterial Calcification in the Noninvasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA(3)CT). Ann Vasc Surg. 2024 Jul; 104:1-9.
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Raeeszadeh-Sarmazdeh M, Greene KA, Sankaran B, Downey GP, Radisky DC, Radisky ES. Directed evolution of the metalloproteinase inhibitor TIMP-1 reveals that its N- and C-terminal domains cooperate in matrix metalloproteinase recognition. J Biol Chem. 2019 06 14; 294(24):9476-9488.
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Bartmann J, Frankenberger M, Neurohr C, Eickelberg O, Noessner E, von Wulffen W. A novel role of MMP-13 for murine DC function: its inhibition dampens T-cell activation. Int Immunol. 2016 10; 28(10):473-487.
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Wiggins-Dohlvik K, Merriman M, Shaji CA, Alluri H, Grimsley M, Davis ML, Smith RW, Tharakan B. Tumor necrosis factor-a disruption of brain endothelial cell barrier is mediated through matrix metalloproteinase-9. Am J Surg. 2014 Dec; 208(6):954-60; discussion 960.
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Purcell BP, Lobb D, Charati MB, Dorsey SM, Wade RJ, Zellars KN, Doviak H, Pettaway S, Logdon CB, Shuman JA, Freels PD, Gorman JH, Gorman RC, Spinale FG, Burdick JA. Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition. Nat Mater. 2014 Jun; 13(6):653-61.
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Rajashekhar G, Shivanna M, Kompella UB, Wang Y, Srinivas SP. Role of MMP-9 in the breakdown of barrier integrity of the corneal endothelium in response to TNF-a. Exp Eye Res. 2014 May; 122:77-85.
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Kaneshiro B, Edelman A, Carlson N, Morgan K, Nichols M, Jensen J. Treatment of unscheduled bleeding in continuous oral contraceptive users with doxycycline: a randomized controlled trial. Obstet Gynecol. 2010 Jun; 115(6):1141-1149.
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Unal R, Yao-Borengasser A, Varma V, Rasouli N, Labbate C, Kern PA, Ranganathan G. Matrix metalloproteinase-9 is increased in obese subjects and decreases in response to pioglitazone. J Clin Endocrinol Metab. 2010 Jun; 95(6):2993-3001.
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Chiappori AA, Eckhardt SG, Bukowski R, Sullivan DM, Ikeda M, Yano Y, Yamada-Sawada T, Kambayashi Y, Tanaka K, Javle MM, Mekhail T, O'bryant CL, Creaven PJ. A phase I pharmacokinetic and pharmacodynamic study of s-3304, a novel matrix metalloproteinase inhibitor, in patients with advanced and refractory solid tumors. Clin Cancer Res. 2007 Apr 01; 13(7):2091-9.
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