 Angiotensin-Converting Enzyme Inhibitors
"Angiotensin-Converting Enzyme Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
| Descriptor ID |
D000806
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| MeSH Number(s) |
D27.505.519.389.745.085
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| Concept/Terms |
Angiotensin-Converting Enzyme Inhibitors- Angiotensin-Converting Enzyme Inhibitors
- Angiotensin Converting Enzyme Inhibitors
- Inhibitors, Kininase II
- Kininase II Antagonists
- Kininase II Inhibitors
- Angiotensin I-Converting Enzyme Inhibitors
- Angiotensin I Converting Enzyme Inhibitors
- Antagonists, Angiotensin-Converting Enzyme
- Antagonists, Angiotensin Converting Enzyme
- Antagonists, Kininase II
- Inhibitors, ACE
- ACE Inhibitors
- Inhibitors, Angiotensin-Converting Enzyme
- Enzyme Inhibitors, Angiotensin-Converting
- Inhibitors, Angiotensin Converting Enzyme
- Angiotensin-Converting Enzyme Antagonists
- Angiotensin Converting Enzyme Antagonists
- Enzyme Antagonists, Angiotensin-Converting
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Below are MeSH descriptors whose meaning is more general than "Angiotensin-Converting Enzyme Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Angiotensin-Converting Enzyme Inhibitors".
This graph shows the total number of publications written about "Angiotensin-Converting Enzyme Inhibitors" by people in this website by year, and whether "Angiotensin-Converting Enzyme Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 1 | 0 | 1 | | 1998 | 1 | 1 | 2 | | 1999 | 1 | 1 | 2 | | 2000 | 2 | 0 | 2 | | 2001 | 3 | 1 | 4 | | 2002 | 2 | 4 | 6 | | 2003 | 1 | 3 | 4 | | 2004 | 3 | 3 | 6 | | 2005 | 4 | 1 | 5 | | 2006 | 2 | 2 | 4 | | 2007 | 5 | 4 | 9 | | 2008 | 5 | 3 | 8 | | 2009 | 3 | 2 | 5 | | 2010 | 3 | 6 | 9 | | 2011 | 3 | 3 | 6 | | 2012 | 1 | 2 | 3 | | 2013 | 2 | 3 | 5 | | 2014 | 2 | 3 | 5 | | 2015 | 4 | 3 | 7 | | 2016 | 2 | 5 | 7 | | 2017 | 4 | 2 | 6 | | 2018 | 2 | 4 | 6 | | 2019 | 1 | 2 | 3 | | 2020 | 2 | 1 | 3 | | 2021 | 2 | 7 | 9 | | 2022 | 1 | 6 | 7 | | 2023 | 0 | 5 | 5 | | 2024 | 3 | 4 | 7 | | 2025 | 1 | 1 | 2 | | 2026 | 2 | 0 | 2 |
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Below are the most recent publications written about "Angiotensin-Converting Enzyme Inhibitors" by people in Profiles.
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Jacobs JA, Greene T, Vanneman ME, Kean J, Carter SJ, Shah KS, Pandey A, Derington CG, Zheutlin AR, Fang J, Stehlik J, Fonarow GC, Bress AP. Time to Quadruple Therapy After Initial Diagnosis of Heart Failure With Reduced Ejection Fraction. JAMA Cardiol. 2026 06 01; 11(6):506-514.
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Denburg MR, Goodwin Davies AJ, Maltenfort MG, Mitsnefes MM, Flynn JT, Neu AM, Dixon BP, Glenn DA, Gluck CA, Harshman LA, Katsoufis CP, Leonard MB, Modi ZJ, Pan CG, Patel HP, Patterson LT, Verghese PS, Wilson AC, Jovanovska A, Levondosky R, Levondosky M, Dickinson K, Wieand K, Razzaghi H, Li L, Chen Y, Forrest CB. Comparative Effectiveness of Antihypertensive Medications in Children With Chronic Kidney Disease. JAMA Pediatr. 2026 May 01; 180(5):546-555.
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Chang HY, Liao CT, Heidenreich PA, Allen LA, Sung SH, Chen WJ, Wang TD, Li YH, Hsu CY, Wu YW, Huang N. Implementation of the Get With The Guidelines-Heart Failure Adherence to Science, Implementation in Asia (GWTG-HF A.S.I.A.) Program in Taiwan. J Am Heart Assoc. 2026 Jan 06; 15(1):e047097.
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Derington CG, Berchie RO, Scharfstein DO, Andrews RM, Greene TH, Xu Y, King JB, Supiano MA, Sonnen JA, Williamson J, Pajewski NM, Pruzin JJ, Cohen JB, Bress AP. Effect of Initiation and Continuous Adherence to ARBs Versus ACEIs on Risk of Adjudicated Mild Cognitive Impairment or Dementia. J Gerontol A Biol Sci Med Sci. 2025 06 10; 80(7).
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Ruha AM, Spyres MB, Culbreth R, Wolk B, Hoyte C, Campleman S. Systemic toxicity after rattlesnake envenomation in patients using angiotensin converting enzyme inhibitors: A North American Snakebite Registry study. Toxicon. 2025 Apr; 258:108292.
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Shoji S, Kaltenbach L, Granger BB, Fonarow GC, Al-Khalidi HR, Albert NM, Butler J, Allen LA, Lanfear DE, Thibodeau JT, Chapman BM, Oliver-McNeil SM, Felker GM, Pina IL, Granger CB, Hernandez AF, DeVore AD. Guideline-Directed Medical Therapy After Hospitalization for Acute Heart Failure: Insights From the CONNECT-HF. J Am Heart Assoc. 2024 Dec 17; 13(24):e036998.
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Zheng J, Sandhu AT, Bhatt AS, Collins SP, Flint KM, Fonarow GC, Fudim M, Greene SJ, Heidenreich PA, Lala A, Testani JM, Varshney AS, Wi RSK, Ambrosy AP. Inpatient Use of Guideline-Directed Medical Therapy During Heart Failure Hospitalizations Among Community-Based Health Systems. JACC Heart Fail. 2025 Jan; 13(1):43-54.
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Ku E, Inker LA, Tighiouart H, McCulloch CE, Adingwupu OM, Greene T, Estacio RO, Woodward M, de Zeeuw D, Lewis JB, Hannedouche T, Jafar TH, Imai E, Remuzzi G, Heerspink HJL, Hou FF, Toto RD, Li PK, Sarnak MJ. Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers for Advanced Chronic Kidney Disease : A Systematic Review and Retrospective Individual Participant-Level Meta-analysis of Clinical Trials. Ann Intern Med. 2024 07; 177(7):953-963.
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Ku E, Tighiouart H, McCulloch CE, Inker LA, Adingwupu OM, Greene T, Estacio RO, Woodward M, de Zeeuw D, Lewis JB, Hannedouche T, Hou FF, Jafar TH, Imai E, Remuzzi G, Heerspink HJL, Toto RD, Sarnak MJ. Association between Acute Declines in eGFR during Renin-Angiotensin System Inhibition and Risk of Adverse Outcomes. J Am Soc Nephrol. 2024 Oct 01; 35(10):1402-1411.
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Heerspink HJL, Eddington D, Chaudhari J, Estacio R, Imai E, Goicoechea M, Hannedouche T, Haynes R, Jafar TH, Johnson DW, van Kruijsdijk RCM, Lewis JB, Li PKT, Neuen BL, Perrone RD, Ruggenenti P, Wanner C, Woodward M, Xie D, Greene T, Inker LA. A meta-analysis of randomized controlled clinical trials for implications of acute treatment effects on glomerular filtration rate for long-term kidney protection. Kidney Int. 2024 10; 106(4):688-698.
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